Sentences with word «rivastigmine»

Thus, cholinergic modulation by rivastigmine treatment led to enhanced neurogenesis and the suppression of gliosis, which together ameliorated the memory decline in T2DM - AD model mice.

By two hippocampal - dependent memory tests, the Morris water maze and contextual fear conditioning, rivastigmine improved the memory

These include rivastigmine (the only medication approved by the FDA for dementia in PD), donepezil and galantamine.

Rivastigmine did not change the insulin abnormality or amyloid pathology in these mice.

The number of newborn neurons in the hippocampal dentate gyrus was 1138 ± 324 (Ave ± SEM) in wild - type littermates, 2573 ± 442 in T2DM - AD - Vehicle, and 2165 ± 300 in T2DM - AD - Rivastigmine mice, indicating that neurogenesis was accelerated in the two T2DM - AD groups (n = 5, p < 0.05).

In addition, the hippocampus of T2DM - AD - Vehicle mice showed increased proinflammatory cytokines IL - 1β and TNF - α and gliosis, and rivastigmine treatment blocked these inflammatory reactions.

By two hippocampal - dependent memory tests, the Morris water maze and contextual fear conditioning, rivastigmine improved the memory... deterioration of the T2DM - AD mice (n = 8, p < 0.01).

The institute instead ruled that donepezil, rivastigmine and galantamine would only be made available to people at the moderate stage of the disease, saying the medicine did «not make enough of a difference» for some patients.

A multi-center, double - blind placebo study in collaboration with Duke University testing the usefulness of an FDA approved drug, Rivastigmine, on memory and language function in children with Down syndrome ages 10 - 17 years.

Donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne) are medications called cholinesterase inhibitors that are often prescribed to AD symptoms, including attention, memory, and behavior.

In this study, we administered a broad - spectrum cholinesterase inhibitor, rivastigmine (2 mg / kg / day, s.c.), into T2DM - AD mice for 6 weeks, and evaluated their memory performance, neurogenesis, and neuroinflammatory reactions.

Keywords: Acetylcholinesterase, Alzheimer's disease, gliosis, high - fat diet, inflammation, memory, neurogenesis, rivastigmine, type 2 diabetes mellitus

The dendritic maturation of new neurons in T2DM - AD - Vehicle mice was severely abrogated, and rivastigmine treatment reversed this retarded maturation.

Like its cousins donepezil (Aricept) and rivastigmine (Exelon), galantamine can cause GI symptoms.

Dr. Jicha said memantine is usually added after patients have dosed up to recommended levels of donepezil (Aricept), rivastigmine (Exelon) or galantamine (Razadyne).

Rivastigmine is in the same class of medicines as donepezil (Aricept) and a third drug, galantamine (Razadyne).

Drugs with similar effects to neostigmine, rivastigmine (Exelon patch), which is used to treat human Alzheimer's disease and a similar drug, Donepezil (Aricept) also inhibit (lower) cholinesterase levels.