Sentences with phrase «robust activity in»

«With robust activity in the region, and an increase in both inbound and outbound transactions, Brian's arrival significantly enhances our ability to serve our clients» increasingly complex needs.»

The spring has brought new life into the liquid alternatives market with both March and April seeing robust activity in terms of new fund launches and registrations, as well as fund flows.

Cinnamon oil showed robust activity in two benchmark tests for antioxidant function.

However, ADCs that use derivatives of calicheamicin, which promotes double - stranded DNA breaks, such as GO and inotuzumab ozogamicin, 40,41 have limited activity in cells with high multidrug resistance protein activity, a phenotype found in a significant fraction of AML patients.42 Another ADC, SGN - CD123A, comprising an engineered form of the CD123 - targeting 7G3 antibody conjugated to a synthetic pyrrolobenzodiazepine dimer, which acts via DNA crosslinking, has entered clinical trials after showing robust activity in preclinical models of AML, including those with multidrug resistance.33

«They could be distressed by the election, but did not show psychological symptoms of depression if they have either strong family support or robust activity in these brain regions,» Tashjian said.

Not exact matches

Growth in consumer spending, representing two - thirds of U.S. economic activity, slid to 1.1 percent rate in the first quarter, the slowest pace since the second quarter of 2013 and following the fourth quarter's robust 4.0 percent growth rate.

While Canada's National Shipbuilding Procurement Strategy stirred up some activity here, the outlook for the field is not robust; projections are for an oversupply of engineers versus jobs in the next decade.

«M&A dialogue remains robust despite concerns about the potential impact of changes in America's trade and national security policies on deal activity,» said Stephen Arcano, head of M&A at Skadden.

Global stocks kicked - off the week in a bullish mood Monday, with merger activity and a robust U.S. corporate earnings season helping boost markets in Europe and Asia and set up Wall Street for a positive start to the final trading day of the month.

The latest survey highlighted ongoing supply - chain pressures across the manufacturing sector, in part reflecting a further robust increase in purchasing activity.

The global synchronized economic expansion, a business - friendly administration in Washington, solid corporate credit quality, modest default activity, robust equity markets and a favorable supply - demand balance set a strong backdrop for high yield in the New Year.

Cameron Belsher, leader of the mergers and acquisitions group at McCarthy Tétrault in Toronto, says this is the «most robust it's been since 2006 and 2007,» noting that much of the M&A activity is «not necessarily in the public domain,» but has been dominated by private equity firms.

Having more resilient banks with sufficient capital and liquidity reduces the probability of widespread liquidity crises.9 That would help make market - making more robust, though probably at lower levels of activity in normal times.

A sustained market rally and robust client activity in 2017 translated into a year of gains for Asia's private banks, whose combined assets under management (AUM)-- excluding China onshore — surged past US$ 2 trillion for the first time.

Recent indicators suggest that private demand has continued to grow at a robust rate, with a pick - up in both consumer spending and housing activity, following an apparent moderation in growth in the June quarter.

We believe corporate activity will remain robust in 2017 and potentially increase as the year progresses.

In Canada, the principles of civil society supported by our regulatory systems are equally essential to supporting robust policy and regulatory consultation and decision - making on PRC investments and activities.

The US economy continued to expand in September of this year, with some of the key economic data in October pointing to robust economic activity that could well extend into the last three months of 2017.

Large contributions to employment growth over the past year were also made by the public sector and the property and business services industry, which has benefited from robust sales activity in housing markets.

The effect of this weakness in the consumer sector on overall activity was, to some extent, offset by robust growth in business investment.

Activity is also stronger in Hong Kong and remains robust in Indonesia and Malaysia.

«Since opening our Limerick office six years ago, we have prioritized building a robust European operation dedicated to serving clients in the region, as well as supporting the stewardship activities of institutional investors globally,» said Glass Lewis CEO Katherine Rabin.

The warnings come not from the heavily traded futures market, but from less transparent trading activity in crude oil and products markets, where key U.S., European and Russian crude prices have fallen of late, suggesting less robust demand.

We are in a robust position across all key areas of our activity.»

Given the robust activity around the country to provide locally - sourced, taste - tested meals prepared in - house, you may imagine kind lunch ladies whipping up delicious daily offerings.

That's because early, frequent, and effective nursing increases prolactin activity in the breast, which helps assure an abundant and robust milk supply.

The more robust those mental links become, the more confident and calm your little one will be, knowing that he can predict the next activity in his day.

Although citizenship - stripping is morally repugnant and ethically suspect, the Home Office will no doubt hide behind the little - noticed 2002 law that permit such activities in the name of national security — at least until a robust legal challenge is launched.

Going beyond this specific demonstration, if this approach, known as acoustic seafloor geodesy, proves to be robust in the long term (in this case, three to five years are planned, within the limits of the autonomy of the batteries), it could be included within a permanent underwater observatory as an addition to other observations (seismology, gas bubble emission, etc) for in situ real - time monitoring of the activity of this particular fault, or of other active submarine faults elsewhere in the world.

Goetzel explained that employers need to invest in robust, comprehensive health promotion programs for their employees that include physical activity, healthy eating, stress and depression management, and control of blood pressure and diabetes.

In a paper published today in Nature titled «Two distinct RNase activities of CRISPR - C2c2 enable guide - RNA processing and RNA detection,» the researchers were able to show that C2c2 has not one, as previously thought, but two distinct RNA cutting activities that in concert can be harnessed for robust RNA detection and degradatioIn a paper published today in Nature titled «Two distinct RNase activities of CRISPR - C2c2 enable guide - RNA processing and RNA detection,» the researchers were able to show that C2c2 has not one, as previously thought, but two distinct RNA cutting activities that in concert can be harnessed for robust RNA detection and degradatioin Nature titled «Two distinct RNase activities of CRISPR - C2c2 enable guide - RNA processing and RNA detection,» the researchers were able to show that C2c2 has not one, as previously thought, but two distinct RNA cutting activities that in concert can be harnessed for robust RNA detection and degradatioin concert can be harnessed for robust RNA detection and degradation.

«We hypothesized that for a given pair of targets that differ by a single point mutation, a set of mismatches could be identified in the guide RNA that would eliminate Cas9's activity on the normal sequence while maintaining robust activity on the one with a deleterious point mutation.

The targeted therapy rucaparib, which has demonstrated robust clinical activity in ovarian cancer patients with a BRCA mutation, also showed promise in previously treated pancreatic cancer patients with the mutation, according to results from a phase II clinical study.

It enables robust tuning of the composition of catalytic materials to optimize the activity, selectivity, and stability, and the application will be very broad in energy conversions and chemical transformations,» says Chao Wang, assistant professor of chemical and biomolecular engineering at Johns Hopkins University and one of the study's authors.

The very large ensemble of solar - like stars included in this study enables detailed and robust estimates of the relation between chromospheric activity and the occurrence of superflares.

Using this treatment scheme, we observed a robust difference on day 9 in the disease activity indices of wild - type and Rassf1a knockout mice that was significantly inhibited with the use of the RIPK2 inhibitors, especially RIPK2 inhibitor 1 (Fig. 6B; Table 2).

Here we report the development and preclinical characterization of a novel CD123 - targeting ADC, IMGN632, which utilizes a highly potent DNA - alkylating payload, resulting in an ADC with robust preclinical activity in multiple models of AML.

Inulin and guar are prebiotic substances that provide food for the live organisms in Probiotic Select ™ and are intended to help promote robust probiotic activity following delivery to the lower intestinal tract.

The onset of physical activity should involve preparing the body for what is to follow — a more robust workout.This means first increasing the lung's capacity to take in oxygen and exhale carbon dioxide, increasing flexibility in the joints, elevating blood fats to make more muscle energy available, and improving blood and lymph circulation in the muscles.

Women at Sundance offers a robust year - long fellowship that includes mentorship, professional coaching made possible by The Harnisch Foundation in partnership with Renee Freedman & Co, travel grants to the Sundance Film Festival to participate in curated activities, entree into branded and episodic content, and bespoke year - round support.

A + allows two or more advisory groups to at times meet together and engage in more robust morning activities that build relationships, get them moving, and stimulate the mind — all in a safe, self - controlled way.

I will say that the state elections this year will determine just how robust school choice activity will be in 2019.

Students use the digital resources independently to supplement teacher - led activities, resulting in meaningful learning experiences that foster a deep, robust understanding of concepts.

Teachers at Hood River come together on more robust cross-curricular activities rooted in their community, ranging from field trips to the Columbia River Gorge to launching a weather balloon into the Earth's atmosphere.

At Democracy Prep Public Schools we not only have a robust civics curriculum in the classroom, we also have our scholars engage in authentic civic activities in their communities.

Offering a robust complement to the academic program, we integrate the arts, library media, visual arts, physical education and movement, and STEM (science, technology, engineering, and mathematics) which, launched in 2013, includes the exciting Sea Perch activities.

It also runs a robust extended day program that offers supplemental academic instruction for struggling students and cultural enrichment activities in the areas of music, dance, sports, and math.

A robust group of staff worked painstakingly on formatting the curriculum following the «model» and creating for each class an index box filled with laminated cards of character - activities for each of the units in the LbD sourcebooks.

CLOTH helps provide a robust after - school program with activities ranging from homework help to the Grrrl Alliance which discusses gender and LGBTQ issues, bringing in guest speakers from the community.

With a robust parent involvement component, these activities are reinforced in multiple settings with family participation.