Sentences with phrase «robust immune response»

No data are yet available for trials in children, who typically have much less robust immune responses to the seasonal influenza vaccine and require a second dose.

Additionally, this approach has the potential to stimulate a more robust immune response through an adjuvant effect of the immune mismatch between AST - VAC2 and patients.

The researchers manufactured a mutant influenza virus that is susceptible to one of the body's primary immune defense mechanisms and has generated induced robust immune responses in animal models.

BivWC, they found, induced development of robust immune responses following the first dose of vaccine.

«We chose to pursue a vaccine made from live virus that has been sufficiently attenuated, or weakened, to be safe, and is able to illicit robust immune response to protect us from Zika virus infection.

It is not yet known whether this lack of efficacy is due to an insufficiently robust immune response, to failure of allele - specific antibodies to protect against the wide array of AMA1 variants, or because immune responses to AMA1 alone are simply unable to prevent clinical malaria.

«Zika vaccine induces robust immune responses in three phase 1 trials.»

We find that a single administration of the MN patch induces robust immune responses in a B16F10 mouse melanoma model compared to MN without degradation trigger or intratumoral injection of free aPD1 with the same dose.

Mice raised in a challenging environment had more robust immune responses and hormonal changes, factors that may help protect against cancer

Researchers will also have to examine if triggering a robust immune response to the virus puts people at risk, Sullivan notes, because a frenzied immune system response is what destroys lung tissue and sometimes proves deadly when people are infected with H5N1, a type of avian flu.

The only children who tend to get this infection are preterm infants of very low birth weight who haven't yet developed a robust immune response.

The U.S. National Institute of Allergy and Infectious Diseases (NIAID) is coordinating five different trials at eight different sites around the country, which are testing whether two doses of the vaccine will be necessary to stimulate a robust immune response.

They found that, while the grafts of undifferentiated iPS cells harbored large numbers of T cells of only a few specificities — indicating a robust immune response — those found in grafts of the two types of endothelial cells were more diverse, suggesting a more limited response associated with a phenomenon known as self - tolerance.

The company now has an array of fully human antibodies in its pipeline created with its proprietary VelocImmune mouse, which has been engineered to express human antibody genes while still mounting a robust immune response by making antibodies with fully human variable regions and mouse constant regions.

It «prevents pathology in the brain and gives the mice a chance to develop a robust immune response,» said Kumar.

The «primer» pandemic influenza vaccine — made from live but weakened virus — introduces the immune system to H7N9 influenza virus, and subsequent vaccination with the «booster» inactivated virus vaccine recalls a more robust immune response.

TAC mice exposed to tumors as late as six weeks after the Bifidobacterium transfer were still able to mount a robust immune response.

Pawelec G, Ouyang Q, Wagner W, Biol D, Wikby A. Pathways to a robust immune response in the elderly.

Antibodies target the viral antigenic proteins, activating a robust immune response to target and destroy the Chikungunya virus, so it can not cause an infection.

Results, which will be presented at R4P 2014, show that the regimen was safe and elicited a robust immune response in South Africans.

In his Ph.D. research at Harvard Medical School, Chan engineered dengue virus so that instead of proliferating without being detected by the immune system, it would instead trigger a robust immune response.

Preliminary test of this vaccine component have elicited a robust immune response to the vaccine.

Supports apoptosis, and natural killer cells to give a more youthful and robust immune response.

A number of nutrients play well - defined roles in the maintenance of a robust immune response, optimal energy, and overall health.

Due to the cat's robust immune response to heartworm infection, some data suggest that greater than 90 % of infective L3 larvae do not make it all the way to adulthood.

When the immune system is exposed to antigens via different routes, a more robust immune response may be achieved