Sentences with phrase «robust immune responses»

The researchers manufactured a mutant influenza virus that is susceptible to one of the body's primary immune defense mechanisms and has generated induced robust immune responses in animal models.

We find that a single administration of the MN patch induces robust immune responses in a B16F10 mouse melanoma model compared to MN without degradation trigger or intratumoral injection of free aPD1 with the same dose.

BivWC, they found, induced development of robust immune responses following the first dose of vaccine.

No data are yet available for trials in children, who typically have much less robust immune responses to the seasonal influenza vaccine and require a second dose.

Mice raised in a challenging environment had more robust immune responses and hormonal changes, factors that may help protect against cancer

The only children who tend to get this infection are preterm infants of very low birth weight who haven't yet developed a robust immune response.

They found that, while the grafts of undifferentiated iPS cells harbored large numbers of T cells of only a few specificities — indicating a robust immune response — those found in grafts of the two types of endothelial cells were more diverse, suggesting a more limited response associated with a phenomenon known as self - tolerance.

The company now has an array of fully human antibodies in its pipeline created with its proprietary VelocImmune mouse, which has been engineered to express human antibody genes while still mounting a robust immune response by making antibodies with fully human variable regions and mouse constant regions.

The «primer» pandemic influenza vaccine — made from live but weakened virus — introduces the immune system to H7N9 influenza virus, and subsequent vaccination with the «booster» inactivated virus vaccine recalls a more robust immune response.

TAC mice exposed to tumors as late as six weeks after the Bifidobacterium transfer were still able to mount a robust immune response.

Pawelec G, Ouyang Q, Wagner W, Biol D, Wikby A. Pathways to a robust immune response in the elderly.

Antibodies target the viral antigenic proteins, activating a robust immune response to target and destroy the Chikungunya virus, so it can not cause an infection.

Results, which will be presented at R4P 2014, show that the regimen was safe and elicited a robust immune response in South Africans.

Additionally, this approach has the potential to stimulate a more robust immune response through an adjuvant effect of the immune mismatch between AST - VAC2 and patients.

In his Ph.D. research at Harvard Medical School, Chan engineered dengue virus so that instead of proliferating without being detected by the immune system, it would instead trigger a robust immune response.

Preliminary test of this vaccine component have elicited a robust immune response to the vaccine.

A number of nutrients play well - defined roles in the maintenance of a robust immune response, optimal energy, and overall health.

Due to the cat's robust immune response to heartworm infection, some data suggest that greater than 90 % of infective L3 larvae do not make it all the way to adulthood.

In dogs it has been demonstrated that when intranasal Bordetella bronchiseptica vaccines are used for initial vaccination and injectable vaccines are used for subsequent doses, immune responses may be improved.3, 4 Similar techniques combining oral and injectable vaccines have been demonstrated to provide a more robust immune response in humans.5 Zoetis is excited to be the only company to offer veterinarians the capability to use this concept for vaccination of their canine patients against B.bronchiseptica.

Not exact matches

The researchers said the dye solution appeared to produce a robust anti-tumor immune response and may be safer than existing immunological agents.

«By slowing down virus budding, we may allow an individuals immune system a chance to develop a robust and a protective response,» Harty said.

One of the most robust alterations was observed in the JAK - STAT3 pathway and the production of serum amyloid A (SAA)-- a protein which has only recently been identified as a key player in the body's immune response.

Instead of stirring up powerful T cells through an injected amyloid vaccine, they used a nasal spray containing two drugs that provoke a less robust but more manageable immune response.

While this approach has had some clinical success, in most cases, the immune response resulting from dendritic cell vaccines is short - lived and not robust enough to keep tumors at bay over the long run.

As such the HIV llama vaccination model is robust and reproducible and demonstrates the potential of a mammalian immune system to produce broadly HIV neutralizing antibodies in response to immunization.

They noticed that mice purchased from Jackson Laboratory (JAX) tended to have a robust spontaneous immune response to small melanoma tumors implanted under their skin.

Unlike the other groups, these children were perfectly capable of making a robust, protective immune response to vaccines.

Presentation of these epitopes to the immune system may elicit a robust anti-tumor response.

Our AST - VAC immunotherapy programs employ three common elements of dendritic cells, telomerase antigen, and the LAMP signal sequence to stimulate robust and specific immune responses to cancer cells (Figure 1).

The combination of functional annotation using RNA - seq and homology - based annotation provides a robust method to characterize the innate immune response across a wide variety of insects, and reveals significant novel features of the Nasonia immune response.

«Sufficient DHA allows the immune system to mount a robust inflammatory response against invading pathogens or damaged tissues and to bring the response quickly to an end once the task has been accomplished.

People over the age of 60 don't mount as robust of an immune response when vaccinated and the protection against infection is often weaker.

We have packed a robust set of key ingredients into one supplement to boost your pup's joint and cartilage health, muscle integrity, and immune response to inflammation:

Regressive infections In approximately 10 % of infections, a cat mounts an immune response that is sufficient to eliminate the virus from the bloodstream, but not robust enough to completely eliminate FeLV DNA from the body.