Sentences with phrase «robust immune responses in»

The researchers manufactured a mutant influenza virus that is susceptible to one of the body's primary immune defense mechanisms and has generated induced robust immune responses in animal models.

We find that a single administration of the MN patch induces robust immune responses in a B16F10 mouse melanoma model compared to MN without degradation trigger or intratumoral injection of free aPD1 with the same dose.

Pawelec G, Ouyang Q, Wagner W, Biol D, Wikby A. Pathways to a robust immune response in the elderly.

Results, which will be presented at R4P 2014, show that the regimen was safe and elicited a robust immune response in South Africans.

In dogs it has been demonstrated that when intranasal Bordetella bronchiseptica vaccines are used for initial vaccination and injectable vaccines are used for subsequent doses, immune responses may be improved.3, 4 Similar techniques combining oral and injectable vaccines have been demonstrated to provide a more robust immune response in humans.5 Zoetis is excited to be the only company to offer veterinarians the capability to use this concept for vaccination of their canine patients against B.bronchiseptica.

Not exact matches

Mice raised in a challenging environment had more robust immune responses and hormonal changes, factors that may help protect against cancer

They found that, while the grafts of undifferentiated iPS cells harbored large numbers of T cells of only a few specificities — indicating a robust immune response — those found in grafts of the two types of endothelial cells were more diverse, suggesting a more limited response associated with a phenomenon known as self - tolerance.

The company now has an array of fully human antibodies in its pipeline created with its proprietary VelocImmune mouse, which has been engineered to express human antibody genes while still mounting a robust immune response by making antibodies with fully human variable regions and mouse constant regions.

One of the most robust alterations was observed in the JAK - STAT3 pathway and the production of serum amyloid A (SAA)-- a protein which has only recently been identified as a key player in the body's immune response.

No data are yet available for trials in children, who typically have much less robust immune responses to the seasonal influenza vaccine and require a second dose.

While this approach has had some clinical success, in most cases, the immune response resulting from dendritic cell vaccines is short - lived and not robust enough to keep tumors at bay over the long run.

As such the HIV llama vaccination model is robust and reproducible and demonstrates the potential of a mammalian immune system to produce broadly HIV neutralizing antibodies in response to immunization.

In his Ph.D. research at Harvard Medical School, Chan engineered dengue virus so that instead of proliferating without being detected by the immune system, it would instead trigger a robust immune response.

A number of nutrients play well - defined roles in the maintenance of a robust immune response, optimal energy, and overall health.

Regressive infections In approximately 10 % of infections, a cat mounts an immune response that is sufficient to eliminate the virus from the bloodstream, but not robust enough to completely eliminate FeLV DNA from the body.