Sentences with phrase «rodent studies»

"Rodent studies" refers to scientific research that is carried out on small mammals such as rats and mice. These studies help scientists understand various aspects of biology, behavior, diseases, and test the effectiveness of treatments before they are used on humans. Full definition
The hope is that the injections will help people recover function lost through injury, as seen in rodent studies in 2005.
In the mid-1990s, Langer was working with colleagues at Harvard Medical School to study the idea of using biomaterials in combination with cells or drugs to improve functioning in people with spinal cord injuries; he published the results of rodent studies in 2002.
Some biologists extrapolate findings from rodent studies of epigenetic inheritance to humans, but others remain skeptical
«Other studies have implicated the VTA in learning based on negative, as well as positive reinforcement, and a recent rodent study found that increasing VTA activation can relieve depression, possibly by increasing motivated behavior.
(17) This is disputed by Uffe Ravnskov who feels that the difference is significant, and points to rodent studies showing statin drugs cause cancer in animals.
Recent rodent studies favor a maternal - mediation hypothesis that considers maternal - care differences induced by neonatal stimulation as the cause of individual differences in offspring development.
Two main researchers, Jonathan D. Buckley and Peter R. C. Howe write, «there is a considerable body of evidence from rodent studies indicating that supplementing the diet with long - chain omega 3 fatty acids can attenuate weight gain and reduce fat, in particular visceral fat.»
The results, combined with rodent studies, raise the possibility of a preliminary — but as yet unestablished — link between the abundance of P. copri and the risk of rheumatoid arthritis.
The same UCSF team of researchers had another paper published last month (November 2017) by the open access journal PLOS Biology titled, «Sugar industry sponsorship of germ - free rodent studies linking sucrose to hyperlipidemia and cancer: An historical analysis of internal documents.»
The same UCSF team of researchers had another paper published last month (November 2017) by the open access journal PLOS Biology titled, «Sugar industry sponsorship of germ - free rodent studies linking sucrose to hyperlipidemia and cancer: An historical analysis of internal documents.»
Harding also argues that because rodent studies suggest that these animals do lose neurons to alcohol, they may be unreliable models for the human hippocampus.
It's fine to make educated guesses based on rodent studies of how something might work in humans.
For today's edition of Dear Mark, I'm talking about a new rodent study has just been released that seems to identify the general low - carbish, Primal - ish way of eating as bad for GI tract health.
Rodent studies reveal why: The mechanisms that control the hunger for and the pleasure from food are inextricably intertwined.
In this article, Dr David Kristensen and colleagues from Copenhagen University Hospital, review the findings from three individual rodent studies that evaluated the effects of paracetamol taken during pregnancy on the development of the reproductive system in female offspring.
The article reviews three separate rodent studies that all report altered development in the reproductive systems of female offspring from mothers given paracetamol during pregnancy, which may impair their fertility in adulthood.
This webinar will discuss the promise CRISPR / Cas9 has for rodent studies along with strategies for developing better models to understand and treat human disease.
PNP Therapeutics, Inc. — a company based on a gene - therapy technology developed by scientists at Southern Research Institute and the University of Alabama at Birmingham (UAB)-- has found an approach that has abolished otherwise unmanageable human cancers in preclinical rodent studies.
Megan: The thing about rodent studies is you keep everything so neat and tidy and only manipulate one variable.
The reason this whole thing came about is because of a couple rodent studies — studies on rats — that showed there were hypothetical thyroid issues from eating very large amounts of cruciferous vegetables.
Don't say it's a stupid rodent study, Arlet Nedeltcheva showed the same thing in humans: hypocaloric diet + circadian disruption = lose more lean mass and less fat mass.
Although EE was not directly measured in the latter rodent studies, the findings are consistent with the physiological principal that energy needs are higher during sleep loss.
Rodent studies show that the number of titin filaments that surround each myosin filament can increase after exercise training (Bellafiore et al. 2009; Hidalgo et al. 2014; Krüger & Kötter, 2016), and this would be expected to increase titin - based stiffness, thereby increasing force during lengthening contractions (Lindstedt et al. 2001; Hidalgo et al. 2014).
To date, very few human intervention studies have tried to replicate the reported effects of alternate - day fasting seen in rodent studies.
The research team still has an estimated two years of rodent studies to complete.
Rodent studies suggest that as they diffuse into circulation, they stimulate the anti-inflammatory arm of the immune system — cells that help you not attack tree pollen and other harmless proteins — preventing allergies and other inflammatory diseases.
Scientists now report results from rodent studies in ACS» Journal of Proteome Research showing that signaling molecules are likely involved in mild cases, also known as concussions.
Rodent studies found at least in the short - term, ketogenic diets increased glucose intolerance and insulin resistance.
The finding, based on rodent studies, was published recently in the Journal of the American Chemical Society.
A new rodent study has paved the way for the power of a gluten free diet during the sensitive epigenetic window of pregnancy and postpartum.
The findings support other recent rodent studies that showed drugs that enhance the action of BDNF can reduce brain changes and symptoms of Huntington's disease.
The results of the rodent studies also have implications for human health.
And although many of the initial animal studies used mRNAs with pseudouridine, Moderna's new chemistry was already starting to outperform that first generation in rodent studies.
The specifics have yet to be ironed out, but the Amgen team has uncovered a few clues in their rodent studies: They found treated animals had increased activation of certain neurons in the brain that detect blood sugar, and this may have helped them sense when it was time to stop eating.
Furthermore, a rodent study concurrently examined the effects of mid-puberty or adult alcohol exposure on voluntary alcohol consumption in later life by 20 male Wistar rats.
Based on evidence from rodent studies, researchers used eight rhesus monkeys ranging in age from 5 to 10 years (approximately equivalent to humans from 15 to 30 years of age).
Changes in muscle repair with aging were determined by injecting the old mice and young mice (neither group exercised) with snake venom commonly used to induce muscle injury in rodent studies.
In rodent studies, calorie restriction can extend life span by 20 % to 80 %.
«The rodent studies we're doing right now are giving us a better understanding of how to optimize the timing and amounts of the two drugs.
In another rodent study published this week in Science Translational Medicine a group of researchers from multiple institutions identified a pathway responsible for the formation of amyloid plaques.
Anand, who studies the association between nicotinic receptors and central nervous system disorders, was inspired to pursue a model of human neural biology after encountering disappointing results in a rodent study of an experimental autism drug.
This rodent study investigated whether EA can alleviate hyperalgesia during alcohol withdrawal, potentially reducing the risk of a relapse to drinking, and whether it achieves this effect via action at mu opioid receptors (MORs) located in a brain region called the lateral habenula.
The eyes are the windows into your rodent studies.
Many paradigms used in rodent studies, such as those using mazes, have been successfully adapted to zebrafish studies.
In rodent studies this technique requires optical fiber implantation, but as they are transparent, fiber optics are not needed in studies with zebrafish larvae.
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