(17) This is disputed by Uffe Ravnskov who feels that the difference is significant, and points to
rodent studies showing statin drugs cause cancer in animals.
Another rodent study showed that administration of B. infantis in rats reduced the levels of IFN - γ, TNF - α, and IL - 6 following mitogen stimulation and altered tryptophan, 5 - HIAA, and DOPAC levels in the frontal cortex and amygdala [37].
Rodent studies show that the number of titin filaments that surround each myosin filament can increase after exercise training (Bellafiore et al. 2009; Hidalgo et al. 2014; Krüger & Kötter, 2016), and this would be expected to increase titin - based stiffness, thereby increasing force during lengthening contractions (Lindstedt et al. 2001; Hidalgo et al. 2014).
Not exact matches
The
study, just published in Science,
showed that the creation of what the researchers are calling microtumors can help predict drug effectiveness in cancer patients better than the current standard method of testing the drugs on
rodents.
In other
studies, Sonntag's group has
shown that infusing IGF - 1 into the brain improves memory and learning in elderly
rodents.
In particular, the
study showed new protein synthesis in a specific sub-region of the prefrontal cortex known in
rodents as the prelimbic.
The findings support other recent
rodent studies that
showed drugs that enhance the action of BDNF can reduce brain changes and symptoms of Huntington's disease.
MASTER HUNTER Nerve cells in a mouse's amygdala send messages that help the
rodent chase and kill prey such as crickets, a new
study shows.
Studies have
shown that exercise can have both structural and cognitive benefits in
rodent models of pathological conditions like Fetal Alcohol Spectrum Disorders (FASD) and Alzheimer's disease.
Studies in
rodents and in human fetal beta cells have
showed that the responses of very young beta cells to increases in blood glucose are blunted when compared to their more - mature counterparts.
In a
study published last fall, researchers
showed that male prairie voles that had been separated from their female partners for four days — a much shorter amount of separation time than researchers had previously found to affect the voles» physiology — exhibited depressionlike behavior and had increased levels of corticosterone, the
rodent equivalent of the human stress hormone cortisol.
«
Studies in
rodents have
shown that artificially manipulating VTA activity strongly influences behavior, and our work has bridged the gap between
rodent and primate.»
And that could be bad if what happens in laboratory animals also happens in people, because
studies in
rodents show that BPA can trigger a host of harmful changes, from reproductive havoc to impaired blood - sugar control and obesity (SN: 9/29/07, p. 202).
In previous
studies on
rodents, postdoctoral scholar Clemenson and others
showed that exploring the environment resulted in the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networks.
In the new
study, Dr. Greenamyre and his team — led by coauthors Roberto Di Maio, Ph.D., and Paul Barrett, Ph.D., both of PIND — used a well - established
rodent model of PD to
show exactly how alpha - synuclein disrupts mitochondrial function.
A compound that blocks iron - containing enzymes in the brain improves recovery following brain hemorrhage, a new
study in
rodents shows, and it works in an unexpected way.
«Although our
study is in
rodents, the same receptors have been
shown to impact human stress and drug addiction.
Recent
studies have
shown that endorphin blockers do lessen the activation of reward circuits in humans and
rodents that are presented with appetizing food — the subjects eat less.
Studies of germ - free
rodents and other animals on gut - disrupting antibiotics
show that changing microbial communities can impair memory and cause anxiety - like behaviours.
Researchers assumed that African
rodents must have their own menagerie of hantaviruses and that these might infect humans as well — an idea supported by
studies that
showed that some Africans carry antibodies that cross-react with Eurasian hantaviruses.
Foraging may be a source of pleasure for animals:
studies have
shown that
rodents, like the iguanas mentioned previously, tend to prefer finding their own food to eating food provided in a dish.
Since then, he and his colleagues have
shown in lab
studies of
rodents and pythons that these animals grow up bigger and faster when they eat cooked meat instead of raw meat — and that it takes less energy to digest cooked meat than raw meat.
Previous
studies had
shown that in
rodents — and in humans — those who relapsed began consuming more nicotine than they did when first exposed to the drug.
But other
studies of
rodents continue to be published that do
show developmental and functional abnormalities at low doses, including at doses significantly below those found in humans.
Scientists have long known that restricting calories can fend off physiological signs of aging, with
studies in fruit flies, roundworms,
rodents and even people
showing that chronically slashing intake by about a third can...
In a 2005
study, published by the journal Neuron, she and her advisor John Marshall at UC Irvine
showed that when given a choice between two separate rat - sized rooms, the
rodents preferred the one where they remembered getting cocaine on previous days.
In a second
study, published in the journal Stem Cells Translational Medicine, the team
showed that in
rodents they could use the same type of lung cell to successfully treat a model of IPF — a chronic, irreversible, and ultimately fatal disease characterized by a progressive decline in lung function.
And he and his lab are excited about new
studies showing that fasting seems to strengthen normal cells in
rodents while making cancer cells more vulnerable.
Eating onions to increase testosterone levels may seem like a joke, but in a
study that was conducted on
rodents by Iranian scientists it was
shown that onions can increase testosterone levels in
rodents as high as 300 percent.
Studies done on
rodents have
shown that when you are binging on sugary foods dopamine levels increase instead of experiencing a gradual decrease.
Accumulating data suggests that IER may also activate hormesis, and there has been some suggestion that it is thestress associated with fasting, or the alternating periods of anabolism and catabolism, rather than an overall ER is responsible.15, 105 IER (100 % ER / alternate days) in
rodent studies has been
shown to up - regulate the expression ofanti - oxidative 20, 105, anti-apoptotic 20, 21 and pro-angiogenic 21 factors.
Previous experimental
studies showed that diet - induced magnesium deficiency led to elevated serum concentrations of inflammatory cytokines in
rodent models (30 — 33).
First up, what are we to make of a recent
study claiming to
show that «high - fat diets» are harmful to
rodents?
Studies using female
rodents, on the other hand, have
shown that the subjects stop ovulating and menstruating when put on intermittent fasting.
Rodent studies have
shown BPA causes reproductive defects, cancer, and breakdowns in metabolic and immune health.
One
study in
rodents showed that elevated amounts of acetate in the blood suppressed appetite by affecting brain function.
For instance, marijuana has been
shown to suppress the hypothalamic - pituitary axis (HPA) in
rodents, but human
studies suggest variable effects on the HPA axis.
Don't say it's a stupid
rodent study, Arlet Nedeltcheva
showed the same thing in humans: hypocaloric diet + circadian disruption = lose more lean mass and less fat mass.
Scientists have long known that restricting calories can fend off physiological signs of aging, with
studies in fruit flies, roundworms,
rodents and even people
showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.
They have also done
studies showing that
rodents that lack an inflammatory response don't become leptin resistant, giving further support to this hypothesis.
Additionally,
studies have
shown that decreasing serotonergic activity through intraperitoneal (IP) administration of a serotonergic antagonist increases the amount of time that
rodents can run before they reach the point of exhaustion [219].
There was a
study on the stomach contents of feral cats and it
showed that most of their diet consisted of
rodents and insects - a very low percentage of song birds.
The cats in the
study were
shown a variety of images, and the most popular programs depicted birds,
rodents and fish — natural prey for felines.
A further
study on the semi-precocious
rodent Octodon degus [132]
showed that short, repeated separations in the first three weeks of life resulted in significant alterations of density of neurons releasing corticotropin releasing factor (CRF) in brain regions involved in emotion regulation.
Additionally, some
studies with institutionalized children experiencing neglect and transitioning into nurturing homes through adoption
show an initial normalization of diurnal cortisol slopes, 10 but other
studies show that years later dysregulated cortisol patterns are present again when compared with nonadopted children.33 This raises the possibility that early adversity may have programming effects on the HPA axis that become apparent with time and development, similar to what has been observed in experimental
studies in primates and
rodents.34 The follow - up assessment in the present
study is ideally suited for testing the possibility of long - lasting reversals in HPA functioning.