For many years it has been known that the eye contains two types of receptor,
rods and cones which react to light and enable vision.
Not exact matches
Who has so made it that the hundred millions of
rod and cone cells
which together make sight possible, are so co-ordinated that they can give sight?
PRA is caused by the degeneration of the photoreceptor cells,
rods and cones,
which are needed for dark
and day light vision, respectively.
And astronomers illuminate their sky charts with red light, which makes objects visible to the cone cells without affecting the red - blind rod cells and forcing the dark - adaptation process to begin all over aga
And astronomers illuminate their sky charts with red light,
which makes objects visible to the
cone cells without affecting the red - blind
rod cells
and forcing the dark - adaptation process to begin all over aga
and forcing the dark - adaptation process to begin all over again.
The trick was to use a new synthetic switch to confer light sensitivity on the retinal ganglion cells in these mice,
which normally respond to signals from the
rods and cones upstream of them.
Through additional experiments, Meister
and his team discovered how the J - RGC compares signals from the ultraviolet
cones to signals from
rods,
which are also sensitive in the green part of the spectrum.
Cones are specialized in bright environment
and detect colors while
rods are used in dim light but are monochrome,
which is why we see in black
and white at night.
Genetic defects cause photoreceptor degeneration,
which are majorly classified into
rod -
cone dystrophy called retinitis pigmentosa (
rods initially degenerate, followed by
cone degeneration),
cone -
rod dystrophy (
cone degeneration, followed by
rod degeneration),
and Leber congenital amaurosis (LCA).
Horizontal cells process visual information by integrating
and regulating input from
rod and cone photoreceptors,
which allow eyes to adjust to see well in both bright
and dim light conditions.
Behind the photoreceptors is another layer of cells called retinal pigment epithelium (RPE),
which support the
rods and cones by delivering nutrients from the bloodstream
and removing waste that the
rods and cones generate.
Among the newly funded investigations are: the development of animal models of diabetic eye disease to learn how fenofibrate, a drug clinically - approved to treat cholesterol, protects the eye from diabetes - related damage; the development of a specialized camera to capture how the retina's
rods and cones (responsible for turning light energy into shapes
and colors) work in health
and how they fail in retinal diseases;
and the exploration of mechanisms by
which intestinal tract bacteria impact the health of the eye.
Replacing
rods and cones is challenging, because these cells have to establish connections with nerve fibers that feed signals into the optic nerve,
which sends those signals to the brain to interpret.
Stem cell research is helping scientists understand how the different cell types in the retina function together,
which has led to exploring ways to replace both
rods and cones and the supporting RPE cells.
They also find the preserved tissues of the eye,
which provides the first record of mineralized
rods and cones in a fossil.
Breeders have a number DNA tests at their disposal to check for the Multi Drug Resistance Gene, hereditary cataracts, Pelger Huet Anomaly, Collie Eye Anomaly
and Progressive
Rod Cone Degeneration (another eye disease), so check
which testing your breeder uses.
This is different from typical progressive retinal degeneration (PRA),
which involves both the
rod and cone cells of the retina causing night blindness
and worsening day vision.
The most common type of PRA is progressive
rod -
cone dysplasia (prcd)
which is known to affect Labrador retrievers
and poodles
and possibly as many as sixty other breeds.
In Australian Shepherds, we commonly do DNA tests for MDR1, a drug reaction mutation; HSF4, a gene with mutations that cause cataracts, one of
which causes most of the cataracts I Aussies; as well as Collie Eye Anomaly
and the progressive
rod -
cone degeneration form of Progressive Retinal Atrophy.
A subsequent electroretinography study identified an initial reduction of the
cone photoreceptor function
which led to the condition being re-classified as a
cone -
rod dystrophy (CRD), rather than a
rod - led PRA,
and the disease was termed CORD1 for
cone -
rod degeneration 1 [36].
Touching on formal elements such as color theory
and Op Art, we will explore the visual effects created within works of art including, but not limited to: pattern, repetition, design, composition, Gestalt psychology
and all forms of optical razzle dazzle that will make the
cones and rods in our eyes forget
which way is up.