Sentences with word «rofecoxib»

Known as a COX - 2 inhibitor, Bextra belongs to the same class of drugs as rofecoxib (Vioxx), which manufacturer Merck yanked from pharmacy shelves last September after safety risks appeared (SN: 10/30/04, p. 286: Available to subscribers at COX - 2 inhibitor pulled off market.).
In addition to the drug rofecoxib, pharmaceutical companies have reportedly used ghostwriting to market sertraline, olanzapine, gabapentin, estrogen replacement therapy, paroxetine, methylphenidate, milnaciprin, venlafaxine and dexfenfluramine.
Using the example of the pain reliever rofecoxib, which was sold under the brand name Vioxx, and the occurrence of heart attack, the researchers reproduced that known association between the two using the new research method.
It states that the practice is «dangerous to public health» because «ghostwritten articles on rofecoxib [Vioxx] probably contributed to»... lasting injury and even deaths as a result of prescribers and patients being misinformed about risks.»»
The COX - 2 inhibitor known as rofecoxib was removed from the market in 2004 after a study revealed that cardiovascular disease risk was increased by the drug.
I was on Vioxx (rofecoxib) and Tylenol 3 (with codeine), maxing out the daily dosages.
Clinical trials of GlaxoSmithKline's diabetes drug Avandia (rosiglitazone) and Merck's anti-inflammatory Vioxx (rofecoxib) revealed an elevated cardiac risk from the drugs, but relevant findings were held back from regulators or never published.
For example, lumiracoxib and rofecoxib were linked to double the risk of heart attack in comparison to placebo, and ibuprofen was linked to over 3 times the risk of stroke.
The researchers conducted a comprehensive analysis of 31 randomised controlled studies and 116,429 individuals using 7 different drugs (ibuprofen, naproxen, diclofenac, etoricoxib, celecoxib, lumiracoxib, rofecoxib) or placebo to give a more accurate picture of the cardiovascular safety of these drugs compared to previous research.
Carprofen is a member of the class of drugs known as NSAIDs (non-steroidal anti-inflammatory drugs), the same class as such common over-the-counter remedies as Advil (ibuprofen), Aleve (naproxen), Orudis (ketoprofen), and aspirin as well as more controversial prescription drug such as Celebrex (celecoxib) and Vioxx (rofecoxib).
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