In the brain, these proteins assume an entirely
different role, helping to regulate neuroplasticity — the ability of neural circuits to reshape themselves
at every
stage of
life.
The police chief
in Fargo and the anti-police campaigner
in Three Billboards — McDormand's two defining movie
roles, two decades apart — are
at very
different stages of their
lives: Marge is about to give birth, Mildred is grieving her teenage child.