Studying zebrafish is a vitally important way to discover what
role genes play in human health and disease.
To see what
role the genes play in spore - to - spore communication, the researchers replaced the genes of one strain with those of a different group.
Geneticists don't yet know what
role the genes play in asthma, which afflicts about 16 million people in the United States.
WASHINGTON — A second cancer later in life is common for childhood cancer survivors, and scientists now have a sense of
the role genes play when this happens.
A better understanding of their functions related to body fat and obesity could provide a better picture of
the roles these genes play in a variety of diseases.
Not exact matches
Alcohol is not the only important factor to consider when trying to reduce your cancer risk — your
genes, exercise regimen, and exposure to pollutants can
play a
role, too.
In other words, these four
genes likely
play a key
role in the biology of the disorder.
Athletigen's process involves taking a sample of an athlete's saliva and subjecting it to genotyping analysis to search for 850,000 different
gene variants that may
play a
role in the formation of athletic traits.
June 19, 2013 — A Cornell University study offers further proof that the divergence of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that
play roles in turning
genes on and off.
Because epigenetics is the real driver of your health status, and diet
plays a major
role in
gene expression (aka epigenetics), at least in this post's animal study!
«
Genes play an important
role, certainly, but it's really exposure that counts in turning a child into a top athlete,» he says.
Following this in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to
play a key
role in the regulation of
gene expression.
«I would say he...
played a significant
role in the restoration of service,» said
Gene Russianoff, staff attorney at the Straphangers Campaign.
The epigenetic impairments reflect changes that increase accessibility of chromatin, a process that enhances
gene transcription, suggesting the impairments
play an important
role in addiction behavior.
It may be that some versions of the
gene also
play a
role in deafness caused by environmental conditions, creating a predisposition to hearing loss.
According to the study, identifying the lncRNAs that
play an unknown
role in regulating
genes involved in deafness will have an impact.
Together, these experiments show that the PERIOD3
gene likely
plays a key
role in regulating the sleep - wake cycle, influencing mood and regulating the relationship between depression and seasonal changes in light availability, the team reports today in the Proceedings of the National Academy of Sciences.
A new meta - analysis suggests that low expression levels of 10 related
gene sets responsible for mitochondrial machinery
play an important
role in this disorder — all previously unlinked to Parkinson's.
Another
gene, PCDH15,
plays a
role in the hair cells» ability to convert sound into brain signals (Molecular Psychiatry, DOI: 10.1038 / MP.2014.8).
When looking for
genes that might
play important
roles in the metabolism of healthy and cancerous liver cells, Wang and his colleagues became interested in a
gene called SLC13A5, which produces a protein that transports citrate into cells.
If this
gene plays a
role in energy homeostasis and energy balance in the context of obesity, Wang reasoned, perhaps it could
play a
role in the energy requirements of liver cancer cells.
No one yet knows the mechanism through which environmental factors would alter these
genes, although stress hormones such as cortisol may be
playing a
role.
1) That while it's possible that
genes may
play some
role in explaining these differences, much of it comes down to culture, environment, and the fact that the questions on IQ tests are all written by graduate students from Connecticut and begin, «Teddy leaves Sag Harbor on the brunchtime jitney...»
Previous studies in identical twins that were raised apart revealed that
genes play a major
role in who becomes obese.
«Our studies are the first, to our knowledge, to identify a
gene that
plays a conserved
role in aggression all the way from flies to humans,» explains Anderson, who is also a Howard Hughes Medical Institute investigator.
«Essentially, we are using the human placenta as a model to identify
genes that
play a key
role in invasion in both the placenta and cancer,» wrote Chi Sutherland, a Ph.D. candidate leading the project, in an email.
The focus thereby was on microRNA — a short, single - stranded RNA molecule that is now recognised as
playing an important
role in
gene regulation.
While most of biology and medicine focus on the key
roles genes and chemicals
play in the formation and control of living systems, the spatial arrangement of the components that make up those systems and the physical forces they experience are being increasingly recognized as equally important.
As might be expected of an autoimmune disease, where the immune system turns on healthy tissue, all the
genes play a
role in controlling the growth and multiplication of cells in the immune system.
The FOXP2
gene is thought to have
played a
role in the evolution of the human brain and the development of language.
Genes also
play a
role in menopause, and two research teams have identified several
gene variants associated with advancing or delaying menopause by as much as two years.
But look much closer, at a genetic level, and you will find that many of the
genes seen in these flies are also present — and
play similar
roles — in humans.
A previous study in mice that suggested that
genes played a
role in IgA levels seen in Crohn's disease, Stappenbeck told Live Science.
All four teams focused their hunts on
gene variations found in at least 10 per cent of the population, while Stefánsson thinks that rarer variants may
play a more significant
role in menarche.
Mutations in the
genes that defend the body against cancer - related viruses and other infections may
play a larger
role in breast cancer than previously thought, according to a study at the University of Illinois at Chicago.
But a new study, published today in Nature, has revealed that m6A
plays a key
role in the regulation of the Sex - lethal (Sxl)
gene, which controls sex determination of the fruit fly Drosophila.
By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular
gene, located on their chromosome 2, and whose presence
plays an important
role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this
gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.
This system
plays a major
role in the regulation of
gene activity, and enables the selective expression of different functions in differentiated cell types.
These
genes play a
role in rewiring the neurons in the nucleus accumbens.
After moving to Berkeley, he arrived at a career crossroads in 1994, when Spyros Artavanis - Tsakonas, then at Yale, discovered and subsequently patented the human relative of the fruit fly
gene notch, which
plays a
role in cell - to - cell interactions and could be an anti-cancer target.
The main difference between the two
genes was in a triplet of amino acids that
plays a
role in determining exactly what acid concentration opens or closes the channel.
The animals lack the
gene for an enzyme called inositol hexakisphosphate kinase 1 (IP6K1), which is known to
play a
role in fat accumulation and insulin sensitivity.
Cells make proteins from RNA they copy from
genes, but some RNAs
play roles by themselves.
Since studies had shown that children in heavily polluted areas of the Central Valley had more infections, and pollution and secondhand smoke contain similar toxic compounds, Nadeau searched for
genes that
played a major
role in fighting infection.
Chemical modifications of DNA
play a big
role in how
genes turn on and off in the human body (SN: 2/14/09, p. 5).
Today, a team of researchers from the University of Geneva (UNIGE), Switzerland, led by Emmanouil Dermitzakis, Louis - Jeantet Professor at the Faculty of Medicine, reveals that this is not always the case and that DNA methylation may
play both a passive and active
role in
gene regulation.
Host
genes of the major histocompatibility complex (the
genes that determine how mammals respond to pathogens)
play a significant
role in how the immune system responds to all pathogens.
In a new take on an old polemic, Ridley acts as mediator between biological and cultural determinists, arguing that
genes and the environment
play equally important
roles in shaping human destiny.
After having conducted a large - scale study performed on cells from the umbilical cords of 204 newborns, the researchers from UNIGE demonstrate that DNA methylation may
play both a passive and active
role in
gene regulation.
«DNMT3A places itself preferably in close vicinity to
genes that
play an important
role for development and makes sure that the DNA methylation around these
genes is maintained,» explains Massimiliano Manzo, lead author of the study.