Sentences with phrase «role in cancer biology»

On top of their positive effect on pathogens, macrophages can also play a negative role in cancer biology.

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These results not only show promise on a new targeted therapy to treat this malignancy, as PI3K inhibitors are already used in the clinical practice, but also unravel a new function of the PI3K kinase in cancer biology through its role in promoting metastasis.

The St. Laurent Institute, a non-profit medical research institute focused on the systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored by the scientific community, may play an important role in cancer.

Petris says that understanding the roles of copper in biology may have far - reaching health implications for the general population because copper underpins many facets of biology, including the growth of cancer tumors and the formation of toxic proteins in Alzheimer's disease.

Dr Toral Gathani, a clinical epidemiologist at the University of Oxford [1], told the 10th European Breast Cancer Conference (EBCC - 10) today (Thursday) that findings from the largest study to date of tumour characteristics in relation to ethnicity suggested that inherent differences in tumour biology between the ethnic groups were unlikely to play a role.

«The findings advance our understanding of the role of lncRNAs in cancer biology and, importantly, broaden the opportunity to use lncRNAs as biomarkers to detect prostate cancer.»

Of note, the current study is part of a recent surge in NYU Langone findings on pancreatic cancer, including studies on how first - responder cells turn off the immune response, the role of the drug nab - paclitaxel in tumor biology, cancer cells» unique fuel sources, and how immune cell infighting drives the disease.

The researchers discovered a single letter variant located in TP53, a gene known to play a central role in tumor biology and for accumulating so called somatic mutations, during the development of cancer in patients.

«Under her leadership, the Ben May Department has played a key role in basic biological research as well as in bridging basic cancer biology and translational research.

HIF - 1 plays important roles in critical aspects of cancer biology, including tumor angiogenesis, regulation of glucose and energy metabolism, invasion, and metastasis.

Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis, allergic rhinitis, immunopharmacological modulation of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the allergic effector unit, mast cell derived tumors: new antibody based treatment, the allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels

We have embarked upon a systems biology initiative to investigate the role of epigenetic regulation of ncRNA / miRNA expression in these cancers, and now propose to extend this initiative from the laboratory ultimately to the bedside of patients.

A role of HUWE1 has been very controversial in the context of cancer biology — some studies report HUWE1 as a tumor suppressor, while other studies show HUWE1 as having the potential to cause cancer.

My background includes three years of professional research experience, including my current role as a graduate research assistant at DEF University's Cancer Research Center and prior experience as a cellular biology research intern for XYZ Corp 3/4 a world leader in cancer research and treaCancer Research Center and prior experience as a cellular biology research intern for XYZ Corp 3/4 a world leader in cancer research and treacancer research and treatment.