Sentences with phrase «role in disease treatment»

Not exact matches

Understanding the role the brain plays in conditions linked to inflammation — such as asthma, arthritis, cardiovascular disease and depression — will help in the development of new treatments to combat them, says Slavich.

Opium has held a pre-eminent role in the treatment of disease since the earliest days of recorded history.

In the search for better treatments for this disease the protein Sclerostin, which plays an important role in bone metabolism, is of major interesIn the search for better treatments for this disease the protein Sclerostin, which plays an important role in bone metabolism, is of major interesin bone metabolism, is of major interest.

«Our ground - breaking discovery that bacteria and fungi both play a critical role in health and disease has tremendous implications not only for understanding the disease process, but also for development of potentially life changing treatments for those who suffer from chronic digestive diseases,» concluded Dr Ghannoum.

«Researchers illuminate key role of NOX proteins in liver disease: Study adds credence to new treatment approach now in clinical trials.»

«Scientifically, she worked on a project that not only revealed an important role for a specific growth factor (VEGF) in the physiology of an ocular structure called the ciliary body but she also demonstrated that there might be unexpected and undesired side effects from a widely used treatment for a variety of ocular diseases.

Now, a study published online April 27th, in the Journal of Immunology, confirms that the cytokine GM - CSF (Granulocyte macrophage colony - stimulating factor) likely plays an important role in human disease and offers a new explanation for why the MS treatment interferon - Beta (INF - β) is often effective at reducing MS attacks.

The findings of the study will prove invaluable to other research studies examining the role of synapse function in the diagnosis and treatment of neurodegenerative and other diseases.

As many of these diseases have no effective treatment, future studies examining the role of glucose in regulating neutrophils and inflammation are critical.»

Thus, based on the robust findings from the current study and until proven otherwise, WBRT may still have an important role for treatment of patients who are not in this specific disease category (i.e., 1 - 3 brain metastases).

«The role this chosen toxin plays in the natural environment potentially could be transferred in the medical field to guide research into treatments for cancer research or neurodegenerative disease,» Professor Garson said.

Leading the agency «means maintaining and expanding America's leading role in medical innovation and in the treatment and eradication of disease,» he said.

This allows researchers to identify all of the components that play a role in a disease, with the ultimate aim of understanding the different subtypes of different diseases and being able to better target therapies and treatments.

«These events predict a worse outcome in TNBC patients suggesting that the LINK - A pathway plays a critical role in this disease and may provide wide - ranging therapeutic treatment targets.»

«By understanding the oxytocin system's dual role in triggering or reducing anxiety, depending on the social context, we can optimize oxytocin treatments that improve well - being instead of triggering negative reactions,» said Jelena Radulovic, the senior author of the study and the Dunbar Professsor of Bipolar Disease at Northwestern University Feinberg School of Medicine.

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

TSRI is internationally recognized for its contributions to science and health, including its role in laying the foundation for new treatments for cancer, rheumatoid arthritis, hemophilia, and other diseases.

Institute research findings, generated through its own research programmes and through its leading role in international consortia, are being used to develop new diagnostics and treatments for human disease.

December 7, 2006 Robert Wissler, MD, PhD, 1917 - 2006 A leading expert on the role of diet in the development, prevention and treatment of cardiovascular disease, Robert W. Wissler, MD, PhD, professor emeritus in the department of pathology at the University of Chicago, died from complications from an infection on Tuesday, November 28.

«Method developed by biomedical scientists could help in treatment of several diseases: Researchers» method measures the efficiency in real time of a processing pathway that plays an important role in protein formation in cells.»

Dr. Cain: I think genetics will increasingly play a role in the diagnosis of diseases and in treatment decisions.

As our knowledge of the role of pathogen and host genomic factors in the prevention and treatment of infectious disease expands, it is critical that we evaluate current legal frameworks to determine the extent to which current genetic privacy laws - for example, both state and federal in the US - may hinder our ability to use genetic information to protect the health of both individuals and the general public.

«Both the efficacy and safety results from the ARIEL3 study reinforce the important role of Rubraca in the treatment of recurrent ovarian cancer and expands the treatment options for patients and physicians battling this disease,» he said.

We investigate the role of genes and proteins in the onset of cancer, with the goal of identifying new treatment targets for this disease.

The goal is to understand the role of these genes and proteins and to see if they are involved in various diseases, and thus may one day serve as viable targets for therapeutic treatments.

Our cardiovascular research has played key roles in advancing the diagnosis, treatment and prevention of cardiovascular disease:

The diverse set of antagonists described in this article will be useful in guiding medicinal chemists to rationally design effective CXCR4 antagonists for the treatment of human diseases where SDF - 1 / CXCR4 axis plays a critical role.

The study, published July 21, 2016, in Scientific Reports, also showed significant changes in the gut microbiome after antibiotic treatment, suggesting the composition and diversity of bacteria in the gut play an important role in regulating immune system activity that impacts progression of Alzheimer's disease.

This paper provides direct evidence for the role of TNF in chronic intestinal inflammation using TNBS colitis in Tg197 mice as a model and encourages further clinical trials with anti-TNF therapeutics for the treatment of Crohn's disease.

In this research position you will play a leading role in discovering and advancing compounds for the treatment of major human diseaseIn this research position you will play a leading role in discovering and advancing compounds for the treatment of major human diseasein discovering and advancing compounds for the treatment of major human diseases.

«These findings have potential implications for the prevention and treatment of human heart disease, once we better understand Irx3's role in the human heart,» said Dr. Bruneau.

Importantly, these mice still had significant improvement in survival compared with immunized mice receiving placebo treatment (average survival 9 d), indicating that IFN - γ continues to play an important role in mortality in enhanced HLH disease.

Presentations included: Genetics Primer & Clinical Updates by Angelika Erwin, MD, PhD, Expanded Carrier Screening — What you Need to Know by Amy Shealy, MS, LGC, Recent Advances in the Treatment and Management of Cystic Fibrosis by Silvia Cardenas, MD, Advances in the Management of Duchenne Muscular Dystrophy by Neil Freidman, MBChB, Autism Genetics — PTEN and beyond by Thomas W. Frazier, PhD, Thoracic Aorta Aneurysm and Dissection by Apostolos «Paul» Psychogios, MD, FACMG, Update on Clinical Breast Cancer Genetics by Holly Pederson, MD, Colon Cancer by Brandie Leach, MS, LGC and The Role of Biomarkers in Current Diagnosis of Alzheimer's Disease by Jagan Pillai, MD, PhD.

This finding reveals unexpected roles for the microbiome and innate immune signalling in the pathogenesis of a cerebrovascular disease, as well as suggesting novel strategies for its treatment.

However, current results point to a possible role for hNPCctx in the treatment of at least some forms of human retinal degenerative diseases and highlight the versatility and efficacy of these cells as therapeutic tools in a broad range of neurodegenerative disorders [10]--[12], [66].

By supporting Directive 2010 / 63 / EU, LERU wishes to call attention to the fundamental importance of the use of animals in research and the vital role it plays in understanding and providing treatment for a range of debilitating and life threatening human diseases such as cancer, primary immunodeficiencies, neuro - degenerative diseases and heart failure.

Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis, allergic rhinitis, immunopharmacological modulation of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the allergic effector unit, mast cell derived tumors: new antibody based treatment, the allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels

The images produced by their work will provide a clearer understanding of how even the smallest changes to the brain play a role in the onset and evolution of neurological diseases, such as Alzheimer's and autism, and perhaps lead to improved treatments or even a cure.

They have clearly projected the future role of neurochemistry in the treatment of neurological diseases.

Dr. Kambadakone highlights the role of this new CT technology in detecting lesions in the liver, assessing response to treatment for abnormalities such as adenoid cystic carcinoma and potentially determining the degree of fibrosis in diffuse liver disease.

It may interest you that there are others in your field who also specialize in the treatment of gum disease who have differing opinions regarding the influential role that diet plays in creating resistance or tendency toward periodontal disease.

1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth

This process of renewing your mitochondria may play a huge role in the prevention of many of the diseases we currently have no acceptable treatment — diseases of excess growth.

· Decreases anxiety and offers promising results as a complementary treatment for depression · Reduces pain and improves function in patients with arthritis · Plays a complementary role in treating asthma to improve respiration · Improves most risk factors associated with cardiovascular disease and diabetes · Enhances sleep quality, even in patients with insomnia

«Can whey protein play a role in the treatment of, and possible reduction in or alleviation of the symptoms of Parkinson's disease?»

It encompasses the genetic uniqueness of each person, the importance of the therapeutic partnership, and the role of environment and lifestyle in the development and treatment of disease.

Some time ago, I was asked by a visitor about whey protein's possible role in the treatment of Parkinson's disease.

In this master class, we explore the gut and the role it plays in the development and treatment of chronic infections like Lyme DiseasIn this master class, we explore the gut and the role it plays in the development and treatment of chronic infections like Lyme Diseasin the development and treatment of chronic infections like Lyme Disease.

Taking into consideration the physical body, mind, and spirit, which all play a role in the expression and treatment of disease.

With bitters, digestive enzyme secretions are increased, helping to promote the complete breakdown of nutrients into their absorbable units, preventing gas formation when large molecules are acted upon by bacteria further down the small intestine.2, 11 The complete breakdown of proteins is particularly important, as the cross reactivity of immune cells between undigested protein molecules and intestinal cells plays an important role in the etiology of conditions such as celiac disease.15 Insulin and glucagon secretions are stimulated, helping to stabilize blood sugar levels.3, 11 Many bitters formulations have been traditionally used in the treatment of type 2 diabetes, and it is interesting to point out that many naturally sweet substances are often paired with some bitterness in nature.4, 11 Herbalist Jim McDonald hypothesizes that our cravings for sweetness may mask cravings for bitterness for this reason.4