Sentences with phrase «role in diseases such»

Oligodendrocytes, a type of brain cell that plays a crucial role in diseases such as multiple sclerosis, are more diverse than have previously been thought, according to a new study led by Sten Linnarsson, Karolinska Institutet / SciLifeLab and Gonçalo Castelo - Branco, Karolinska Institutet.

It's helped Bertozzi capture the first images of glycoproteins, proteins coated with sugars that play a key role in diseases such as cancer.

However, many of these regions are believed to play a role in diseases such as type 1 diabetes and Huntington's disease.

Not exact matches

Fibre is responsible for keeping the digestive system in check and also plays a role in stabilising blood glucose levels and cholesterol which contributes to the prevention of chronic diseases such as heart disease and diabetes.

According to the University of Maryland Medical Center polyunsaturated fatty acids (PUFAs)-- also known as omega - 3 fatty acids — play a crucial role in human brain function, as well as normal growth and development, with research showing that they can also reduce inflammation in addition to helping lower the risk of chronic diseases such as heart disease, cancer, and arthritis.

According to a study by the Journal of Food Science in 2008, eating apples has benefits for the neurological health and plays an important role in reducing the risks of neurodegenerative disorders such as Alzheimer's disease.

Hormones may also play a role in many diseases such as cancer and depression.

In certain medical situations (such as muscular dystrophy, Parkinson's disease), creatine can also have a health - protective role.

It may now be possible to investigate whether the failure of mRNAs to move to the proper part of the cell — or a lack of balance between mRNAs in the high - and low - production areas of the cell — may play a role in such diseases as colitis and Crohn's disease, and possibly also in bowel cancer.

«xIAP has other roles in the cell, such as regulation of cell death, so it is a tricky target for treating inflammatory diseases.

«Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases,» said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH's Channing Division of Network Medicine.

Understanding the role the brain plays in conditions linked to inflammation — such as asthma, arthritis, cardiovascular disease and depression — will help in the development of new treatments to combat them, says Slavich.

They have also been associated with neuroinflammatory diseases such as multiple sclerosis, but no study has shown a role in neurodevelopment disorders.

Such compounds might prevent overstimulation of the glutamate pathway, which appears to play a role in Alzheimer's and other brain diseases.

During the past decade we've learned a lot about the function of these newborn neurons, revealing their possible role in psychiatric and neurological diseases such as mood disorders, schizophrenia and epilepsy.

«Black children were slightly older at the first admission than white children, which could represent a subtle marker of diminished access to medical care or a delay in disease recognition,» said Dr. Dotson, who explained other studies have shown that the role of biology in health disparities in chronic diseases is often modest, and there are many other factors, such as access to care and health literacy, that contribute to disparities in care.

«In a number of these diseases, such as lupus and Sjogren's syndrome, a class of interferon known as type 1 interferon is made in abundance and plays a key role, contributing to the immune dysfunction,» said Mary K. Crow, MD, physician - in - chief at Hospital for Special Surgery and senior study authoIn a number of these diseases, such as lupus and Sjogren's syndrome, a class of interferon known as type 1 interferon is made in abundance and plays a key role, contributing to the immune dysfunction,» said Mary K. Crow, MD, physician - in - chief at Hospital for Special Surgery and senior study authoin abundance and plays a key role, contributing to the immune dysfunction,» said Mary K. Crow, MD, physician - in - chief at Hospital for Special Surgery and senior study authoin - chief at Hospital for Special Surgery and senior study author.

The researchers plan to apply their technique to unsaturated fatty acids to help clarify their role in conditions such as inflammation, and diseases affecting the heart, blood vessels, and nerves, etc...

«The immune system plays such a major role in many disease states.

Inheriting a single X chromosome exposes men to a host of X-linked diseases, such as hemophilia or Duchenne muscular dystrophy, and researchers hope to use the new data to understand more fully the role of genes in other X-linked conditions.

That only adds to the growing interest in NOS - 2 inhibitors, he says: The molecule is also believed to play a role in several neurodegenerative afflictions, such as multiple sclerosis and Parkinson's disease.

Other genetic and environmental factors, such as pesticide exposure, also play a role in the disease.

Yonju Ha, a lead author of this article, said that further studies on this receptor and its role in white blood cell recruitment following tissue injury may aid in the development of new interventions for diseases associated with nerve injury, such as TON, stroke, diabetic retinopathy and glaucoma.

If SOCE operates similarly in mammalian cells, it might have some role to play in diseases where dopamine plays a significant role such as Parkinson's, Attention Deficit Syndromes (ADS) and even schizophrenia.

Prof. Schuelke emphasizes: «Our results are a good example of how the study of rare genetic diseases can provide insights into general disease mechanisms, which may also play a role in other conditions, such as paraplegia, and which may give rise to the development of regenerative therapies.»

To extend their initial findings, the researchers seek to understand the signals that coax these cells to develop, and whether they play roles in other autoimmune diseases, such as lupus, multiple sclerosis, and type 1 diabetes.

The researchers report in the Journal of Neuroscience that in the brain MHCI could play an unexpected role in conditions such as Alzheimer's disease, type II diabetes and autism.

Aquaporins are important in physiological processes such as kidney concentration and spinal fluid secretion, and play a role in several diseases as well.

Senior author Lisa Boulanger, an assistant professor in the Department of Molecular Biology and the Princeton Neuroscience Institute (PNI), said that MHCI's role in ensuring appropriate insulin signaling and synapse density raises the possibility that changes in the protein's activity could contribute to conditions such Alzheimer's disease, type II diabetes and autism.

Scientists from Trinity College Dublin have made a significant breakthrough in understanding the regulation of immune cells that play a pivotal role in allergic diseases such as asthma and eczema.

Dysfunction in telomere maintenance pathways plays an integral role in aging, cancer, and certain rare diseases such as dyskeratosis congenita (DC).

The role of Apelin and Elabela in establishing the circulatory system makes them potential targets in future development of therapeutic applications for illnesses ranging from the various cancers, and cardiovascular diseases, to even metabolic diseases such as diabetes.

While genetics play a role in the development of Lupus, a systemic autoimmune disease that can attack any organ system in the human body, so do environmental triggers, such as particulates in air pollution and ultraviolet light, explains Gaurav Gulati, MD, a physician - researcher at the University of Cincinnati (UC) College of Medicine.

Next steps for the team include identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific markers and explore possible roles for these metabolites in disease progression.

Chaudhry will investigate whether the family of amino acid transporters he discovered while at UCSF may play a role outside the synapse, perhaps in non-neurological diseases such as chronic metabolic acidosis or even cancer.

The hope is the technique could be used to unpick the role of proteins in many complex processes, such as the consolidation of memories, or be used to block the interactions between proteins within cells to help illuminate the processes that underpin disease.

Research findings indicate that abnormal CaSR function and / or abundance play a significant role in the development or progression of several non-communicable diseases (or NCDs) such as Alzheimer's disease, cardiovascular diseases, diabetes, cancer, and degenerative muscle loss.

In addition, the ephrin - Eph system also plays a role in plastic processes, such as learning and regeneration, as well as in tumour growth and neurodegenerative diseaseIn addition, the ephrin - Eph system also plays a role in plastic processes, such as learning and regeneration, as well as in tumour growth and neurodegenerative diseasein plastic processes, such as learning and regeneration, as well as in tumour growth and neurodegenerative diseasein tumour growth and neurodegenerative diseases.

In 2000, 9 years and three postdocs later, Wellington earned a position as assistant professor at the University of British Columbia, where she studies genes that regulate cholesterol metabolism and examines their role in neurodegenerative diseases such as Alzheimer'In 2000, 9 years and three postdocs later, Wellington earned a position as assistant professor at the University of British Columbia, where she studies genes that regulate cholesterol metabolism and examines their role in neurodegenerative diseases such as Alzheimer'in neurodegenerative diseases such as Alzheimer's.

Although other factors, such as a person's lifestyle or environment, may play a role in the onset of the disease, many researchers think genetics is the biggest factor.

Most excitingly, by comparing between individual cells, the team expect to reveal differences which could play key roles in both the early stages of life and the first stages of diseases such as cancer.

NMD is known among the medical community for the role it plays in the development of genetic diseases such as Cystic Fibrosis and some hereditary forms of cancers.

Uncontrolled calcium signaling and ROS in the mitochondria is behind a number of common diseases, such as stroke or heart attack, and is thought to play a role in diseases of aging such as neurodegenerative disease.

Research has shown that lifestyle habits, such as exercise and nutrition, play a crucial role in the development of the disease.

Disturbances in these mechanisms are believed to play a role in the development of neurodegenerative diseases, such as dementia, ALS or Parkinson's disease.

But very little is known about its role in infectious diseases, such as the notorious RNA viruses hepatitis, influenza and the common cold.

Telomere dysfunction — alterations in the structure and / or functioning of telomeres — is one of the molecular mechanisms underlying a number of age - related diseases but, to date, little is known about its possible role in pathologies of the liver such as cirrhosis, hepatitis and liver cancer.

The researchers predicted that the TRPC5 mechanism might play a similar role in other types of progressive kidney disease — even if, in those cases, the damaging feedback loop was kickstarted from chronic disorders such as high blood pressure, rather than a specific genetic mutation.

«The finding that diet can influence sleep has tremendous health implications, given the increasing recognition of the role of sleep in the development of chronic disorders such as hypertension, diabetes and cardiovascular disease,» said St - Onge.

Nevertheless, light is gradually being shed on its role in the control of the overall functioning of the genome, in other words, it regulates important processes in our organism such as immune response and that is where it might be possible to find the causes of auto - immune diseases such as celiac disease.