Sentences with phrase «role in gene expression»

Because epigenetics is the real driver of your health status, and diet plays a major role in gene expression (aka epigenetics), at least in this post's animal study!

Dairy's fatty acids may also play a role in gene expression and hormone regulation.

Such modifications affect chromatin structure and play a significant regulatory role in gene expression.

Exciting recent findings now reveal a new layer of information added to RNAs in the form of chemical marks (the epitranscriptome) that play a critical role in gene expression control.

In a paper published in Nature Genetics, an interdisciplinary research team of scientists from the Centre for Genomic Regulation (CRG)-- including a Centro Nacional de Análisis Genómico (CNAG - CRG) group — in Barcelona, Spain, shows that the three - dimensional organisation of the genome plays a key role in gene expression and consequently in determining cell fate.

The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics research).

Because epigenetics is the real driver of your health status, and diet plays a major role in gene expression (aka epigenetics), at least in this post's animal study!

«Mysterious» non-protein-coding RNAs play important roles in gene expression: Study describes how enhancer RNAs are key to gene expression, possibly cancer mutations.»

Choline also plays roles in gene expression and cell membrane signaling.

Not exact matches

Following this in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to play a key role in the regulation of gene expression.

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

Most of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task of studying the role of a transcription factor (gene - expression regulator), NF B (nuclear factor kappa B), in cancer metastasis.

This system plays a major role in the regulation of gene activity, and enables the selective expression of different functions in differentiated cell types.

These play a key role in controlling gene expression and, thereby help regulate the cell's development, growth and function.

In the past decade or so, researchers have also come to appreciate the key roles played by chromatin proteins and RNA in regulating gene expressioIn the past decade or so, researchers have also come to appreciate the key roles played by chromatin proteins and RNA in regulating gene expressioin regulating gene expression.

Enzymes that chemically modify DNA, known as DNA methyltranferases, play critical roles in regulating gene expression during development, but their role in cancer formation is less clear.

Their study, in the journal Oncotarget, is the most extensive analysis to date of gene expression's role in ccRCC tumor growth and metastasis.

This research tool can be used to better understand the function of histone proteins, which play critical roles in the regulation of gene expression in animals and plants.

The theory holds that histone proteins, which combine with DNA to form chromosomes, are more intimately involved in gene expression than their general role of facilitating or hindering gene activation suggests.

Histones and other proteins, when modified by this process known as acetylation, play critical roles in regulation of gene expression, typically resulting in increased gene expression.

«MicroRNAs, or miRNAs, are short RNA molecules that play a prominent role in regulating gene expression.

L2 plays an important role in cells by activating mRNA decay, a system cells use to turn off gene expression when the proteins encoded by the mRNAs are no longer needed.

Beyond their participation in host defense, increasing evidence suggests that these modifications also play important roles in the regulation of gene expression, virulence and antibiotic resistance.

The researchers also found differences in microRNA expression in bipolar cells — tiny fragments of RNA that play key roles in the «reading» of genes.

Animal studies have suggested that overactivation of TLR7 plays a role in lupus, and a gene variant that increases expression of the receptor has been associated with increased lupus risk in human patients.

DNA is wrapped around proteins called histones, which serve to package the DNA inside the cell nucleus and play an important role in regulating gene expression.

The study also raises questions about the role of histone acetylation in regulating gene expression.

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function by knocking down eRNAs could potentially provide a new strategy for altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby genes.

Other grants will fund work on tomatoes, soybeans, a mustard called Arabidopsis, and cotton, as well as research on the role of stress in gene expression.

«We identified, across the genome, that enhancer RNAs were the most common type of RNA that bound to CBP, and that by making this interaction, eRNAs play a crucial role in regulating CBP activity and gene expression.»

The Lazar lab has been working on HDAC3 for over a decade, focusing on the pivotal role of this enzyme in hormone - mediated regulation of gene expression and metabolism.

It plays an important role in how cells sense their neighbors and, by controlling gene expression, determines which cells should develop into different types and how much they should grow - like a master controller.»

Given its critical role in controlling gene expression, SETDB1 must be precisely regulated to ensure that molecular processes run properly.

In a paper published recently in the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDIn a paper published recently in the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDin the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDin the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDH.

Understanding the best ways to work with RNA and the various RNA detection methods can help scientists advance our understanding of gene expression patterns and elucidate the roles of different genomic elements in cellular function and dysfunction.

Believing that science and medicine are inextricably linked, he decided to do a PhD at the MRC Mill Hill laboratories and investigated the role of regulatory elements in controlling gene expression, graduating in 1996.

Plants perform these regulations mainly by regulating nuclear gene expression and multiple intracellular signaling pathways have been shown to play a role in the genomic response of plants to stress, but the processes are not well understood.

Based on gene expression studies of fat tissue conducted at the USDA HNRCA, the Tufts University researchers initiated studies of the role of FAT10 in adipose tissue and metabolism.

In addition, treatment with Korean red ginseng extract suppressed the expression of RSV - induced inflammatory genes and the formation of chemically reactive molecules containing oxygen, which play a role in virus - induced epithelial damage in RSIn addition, treatment with Korean red ginseng extract suppressed the expression of RSV - induced inflammatory genes and the formation of chemically reactive molecules containing oxygen, which play a role in virus - induced epithelial damage in RSin virus - induced epithelial damage in RSin RSV.

The team also recently obtained a grant from the National Medical Research Council in Singapore to pursue a study using the probe to examine the relationship between key Parkinson's disease - linked genes and MAO - B expression and activity to further understand the causes of the disease and illuminate the role of MAO - B in this.

To get a better idea of the gene's role in development the researchers blocked the expression of the gene in zebrafish.

«Our results support that gene expression responses of PGC - 1α isoforms may have an important role in exercise - induced muscle adaptations,» the researchers stated.

The goal of the NIH program, as described on its website, is «to understand the principles behind the three - dimensional organization of the nucleus in space and time (the fourth dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases.»

This under - expression was particularly interesting because although hundreds of genes have already been identified for their presumed roles in autistic disorders, each one alone can at best only explain 1 % of cases.

What's really impressive about Babar's accomplishment is that he did the work for both papers — one on the role of a population of stem cells in lung cancer development (published in Cell) the other on gene expression in group A Streptococcus (published in PNAS)-- as a participant in summer undergraduate research programs.

A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS / Aix - Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP - HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under - expression may induce certain autistic traits.

But DNA and RNA both appear in an index at the back, and this refers you to the main entry on «Gene», which explains the true role both of DNA and RNA in the context of gene expressGene», which explains the true role both of DNA and RNA in the context of gene expressgene expression.

Single - stranded, noncoding micro-ribonucleic acids (microRNAs), consisting of 18 - 23 nucleotides, play a key role in regulating gene expression.

A study of gene expression in leukemia cells has identified an RNA binding protein that plays an important role in driving the development of cancer.