The main point to be addressed is
the role of adhesion in LPA - mediated motility and the role of integrin - mediated adhesion and contractility.
Current projects are investigating: 1) the expression of inflammatory genes during ischemia and reperfusion of kidneys during urology transplantation and in mouse models; 2) the expression of inflammatory genes and proteins in urine as markers indicating the presence of rejection in renal allografts; and 3)
the role of adhesion molecules and chemokines in directing leukocyte infiltration into organ allografts.
Not exact matches
Henikoff told Malik about his work with proteins — histones — that attach to the central regions
of chromosomes — centromeres — during cell division, maintaining
adhesion between chromosomes most
of the time, but also playing a
role when the chromosomes are pulled apart to prepare them for duplication.
«Wettability plays a key
role in determining the equilibrium contact angles, contact angle hysteresis, and
adhesion between a solid surface and liquid, as well as the retraction process
of a liquid droplet impinged on the surface,» explained Doo Jin Lee, lead author, and a postdoctoral researcher in the Department
of Materials and Engineering at Seoul National University.
Presence
of the M - type sPLA2 receptor on neutrophils and its
role in elastase release and
adhesion.
Regulation
of the catalytic activity
of PTP1B:
Roles for cell
adhesion, tyrosine residue 66, and proline residues 309 and 310.
The
role of tyrosine phosphorylated caveolin - 1 in regulating focal
adhesion dynamics and cancer cell migration.
The work has led him to explore the
role of protein phosphorylation in a diverse array
of cellular functions, including transformation, cell communication, cell
adhesion, cell - cycle regulation, the control
of gene expression, and protein degradation.
Structures
of water channels AQP0 and AQP4 were analyzed by electron crystallography and appear to play a
role in cell
adhesion in addition to water channel functions.
Dr. Zutter focuses on the
role of cell
adhesion molecules in host - tumor interactions.
Our final review article, from the labs
of Maximilian Boesch (Kantonsspital St. Gallen, Switzerland) and Andreas Seeber (Medical University
of Innsbruck, Austria), provides an update on the
role of epithelial cell
adhesion molecule (EpCAM) in cancer stem cells (CSCs) and the epithelial ‐ to ‐ mesenchymal transition (EMT) in colorectal cancer (CRC).
These findings are in accord with the well - established
roles of LFA1 and ICAM1 in supporting
adhesion to and transmigration
of lymphocytes across blood vessel endothelium into tissues (Rot and von Andrian, 2004).