Sentences with phrase «role of aneuploidy»
The role of aneuploidy — in which entire chromosomes or chromosome arms are added or deleted — has remained largely unstudied.
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But recently a number of mainstream scientists have come around, agreeing that aneuploidy may play a role (even if not an exclusive one) in cancer.
Researchers from Leibniz Institute for Age Research — Fritz Lipmann Institute (Jena, Germany) now identified a crucial role of telomeres, the end structures of chromosomes, for sensing cells with a wrong chromosome number, referred to as aneuploidy.
An increasing body of work shows that similarly complex aneuploidy variations play a role in some forms of cancer and we think that the rapid accumulation of NGS genomics data combined with novel in - silico techniques - like the ones developed in our study - will soon lead to a better understanding of the relationships between aneuploidy and allele selection».