Sentences with phrase «role of growth factor»

Cancer biologist Cun - Yu Wang of the University of Michigan in Ann Arbor and his colleagues set out to determine the role of growth factors in a cancer called he

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During the past few decades the emphasis of the economy and the learning curve on the economic growth factors and the understanding of the role the financial sector with the economic growth factors.

There is no time where economic growth factors economists and policy makers denied the role of the financial sector.

This approach attempts to trace the origin and growth of religious ideas and institutions through definite periods of historical development and to assess the role of the factors with which religion interacted during these times.

Involvement in the multitudinous problems of a rapidly expanding urban area or exposure to the increasingly bitter struggle between labor and management or entanglement in the luxuriant and rank growth so abundantly fostered by the new wealth of the «gilded age»: these and other factors caused many men to re-examine their roles as ministers and to seek more effective ways of ministering to the needs of their time.11 Perhaps the most important thing that happened to such men was that they became aware of the many factors bearing on human welfare and thus of importance to the Christian gospel.

Under new supermarkets mananaging director Brad Banducci - who is considered a leading candidate for the role of CEO - Woolworths has put in place a raft of new sales and customer measures to give it more visibility and better analyse the factors behind same - store sales growth.

The role of bioactive components, such as cytokines, hormones, growth factors (GFs) and fatty acids (FAs) is poorly known, but they might be implicated in immune response development.

Growth factors and hormones play a variety of interesting roles.

Yuichi Oike of Keio University in Japan and colleagues initially engineered mice that express large amounts of a protein known as angiopoietin - related growth factor (AGF) in order to study its role in forming blood vessels.

To do so they focused on keratinocytes, a specific type of skin cells with a key role in psoriasis because of their abnormal growth and ability to produce large amounts of inflammation promoting factors.

Patterson, one of the few scientists who began studying the role of immune molecules in neurons before Shatz, has long focused on cytokines, messenger molecules that regulate inflammation in the body and (as Patterson eventually discovered) act as growth factors in the developing brain.

«Scientifically, she worked on a project that not only revealed an important role for a specific growth factor (VEGF) in the physiology of an ocular structure called the ciliary body but she also demonstrated that there might be unexpected and undesired side effects from a widely used treatment for a variety of ocular diseases.

About ten years ago, research results showed that things are not quite as simple as that: «Under most conditions, H2O2 is not an undesired side product but rather an essential chemical messenger that plays an important role in regulating the way in which body cells respond to signals from outside such as hormones and growth factors,» says Dr. Tobias Dick of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).

In addition to its known roles in cancerous cells, STAT3 also is an essential mediator of cytokine and growth factor signals in normal cells that are important for diverse processes including immunity and inflammation.

The study found that the insulin - like growth factor 1 (IGF - 1) hormone, known for its pivotal role in tissue growth, is also capable of increasing the lithium sensitivity of blood cells in bipolar disorder patients in whom lithium was originally ineffective.

This fibroblast - growth - factor pathway plays a crucial role in controlling development, beginning in early development of the embryo and extending through the bone - growth phase after the giraffe is born.

Researchers found an indispensable role of the transcription factor in arresting plant growth under stressful conditions.

Dr. Doyle then trained as a postdoctoral scholar at Stanford University under the mentorship of Dr. Marion Buckwalter, researching the role of transforming growth factor (TGF)- beta signaling after stroke and developing a model of poststroke dementia.

Epidermal growth factor receptor (EGFR) signal transduction plays a major role in growth, proliferation and differentiation of mammalian cells.

But as I said, this is only interesting in terms of a new treatment if these growth factors still have a role to play in the growth and development of the lymphoma after diagnosis.»

The study, performed in an animal model, was the first to identify growth differentiation factor 10, or GDF10, a molecule that previously had no known role in the adult brain, said Dr. S. Thomas Carmichael, the study's senior author and a professor and vice chair for research and programs in the UCLA department of neurology.

It appears that a lack of adequate growth factors plays an important role in the survival of transplanted cells.

«Using new microscopy techniques, we could show that the receptor of a well known growth factor, EGF, plays an important role in tight junction barrier formation in the epidermis.

A marker in bile known as vascular endothelial growth factor (VEGF) plays an important role in the growth of cancerous tumors according to new research presented at the 78th Annual Scientific Meeting of the American College of Gastroenterology.

Decorin is a protein that is part of connective tissue like bone, but that also plays a signaling role, interacting with growth factors to slow the rate that cells divide and multiply, unless turned off by too much p53.

However, contrary to other studies of astrocyte de-differentiation [3, 4], epidermal growth factor (EGF)- mediated signaling had no role in astrocyte to NSC conversion.

His research has also discovered a novel mechanism to regulate neurotrophic growth factor - associated signaling pathways by miRNAs in context of PD and Alzheimer's disease (AD), and a role of dysfunctional bioenergetics in the pathogenesis of late - onset AD.

The pioneering work of Dr. Aiello helped demonstrate the role of vascular endothelial growth factor (VEGF) in diabetic retinopathy and other retinal disorders, as well as the therapeutic potential of VEGF inhibitors in these conditions.

His study highlighted a role for vascular endothelial growth factor (VEGF) in N - methyl - D - aspartate (NMDA) receptor trafficking via the activation of long - term potentiation signaling pathways at the post-synaptic sites (De Rossi et al, 2016).

Human stem / progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling.

Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - 160.

Finally, we demonstrate that treatment of T - 47D cells with epidermal growth factor (EGF), which promotes cell ruffling, stimulates increased accumulation of activated matriptase at the sites of membrane ruffling, suggesting a possible functional role at these sites.

Perhaps a universal role for localized BR biosynthesis adjacent to boundaries of developing organs is to fine - tune cellular growth response in coordination with other cell - specific growth promoting or repressing factors.

Role of IL - 17A, IL - 17F, and the IL - 17 receptor in regulating growth - related oncogene - α and granulocyte colony - stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis.

Role of Connective Tissue Growth Factor in the Retinal Vasculature during Development and Ischemia.

During his doctoral and post-doctoral work under the mentorship of Jeffrey Goldberg, MD, PhD, and Larry Benowitz, PhD, Dr. Trakhtenberg discovered (1) how Set - β and PP2A proteins regulate axon growth; (2) the role of serotonin receptor 2C in neurite growth and processing of visual information; and (3) that inhibiting the transcription factor Klf9 acts synergistically with zinc chelation in stimulating axon regeneration.

The finding is based on studies of mice with altered levels of the growth factor PDGF in neural stem cells, which play a key role in the development of the eye.

From these cell based and clinical studies, we have developed important mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely studied by multiple laboratories.

About Scholar Rock Scholar Rock is discovering and developing a pipeline of innovative new medicines to treat a range of serious diseases in which growth factors play a fundamental role, including neuromuscular diseases, cancer and fibrosis.

At a basic level, the physical stress of the activity triggers the release of a protein called BDNF, or brain - derived neurotrophic factor, a growth factor that supports the health of neurons and plays a role in mental processing and memory.

Impaired medullary circulation and direct toxicity due to a drug metabolite seem to play a critical role in inducing interstitial fibrosis, which can be facilitated by a sustained production of some growth factors and cytokines.

Enhanced fat burning through green and white tea - brown fat cells play key role 13.07.2017 Two cups of green tea daily results in more brown fat 25.04.2017 Animal study: half cup of green tea daily is life extending 15.04.2017 Speed up interval - training fat loss with supplement containing caffeine and green tea 19.01.2016 Green tea boosts fat burning after interval training 30.10.2015 Chin - Shin Oolong Tea contains growth hormone booster 02.10.2015 Green tea healthier and more effective on empty stomach 01.09.2015 EGCG speeds up muscle recovery after period of inactivity 19.05.2015 Green tea inhibits breakdown of fast muscle fibres during long - term inactivity 18.05.2015 Five cups of green tea daily rejuvenates skin 10.09.2014 Quercetin boosts inhibitory effect of green tea for prostate cancer 27.01.2014 Slimming supplement containing ECGC, resveratrol and Grape Seed Extract shown to work in human study 12.01.2014 Tea protects prostate against testosterone 10.12.2013 Green tea speeds up muscle recovery after heavy training 11.11.2013 EGCG protects liver and kidneys, and extends life expectancy 04.08.2013 EGCG and caffeine supplement keeps the cold out 26.02.2013 N - oleyl - phosphatidyl - ethanolamine & EGCG combo makes weight - loss diet easier 03.02.2013 Green tea has a slightly anabolic effect on strength athletes 14.01.2013 Cup of green tea with a meal makes it easier to eat less 18.12.2012 Green tea keeps athletes fit as the years go by 24.10.2012 Mushrooms, green tea reduce chance of breast cancer by factor of 10 13.10.2012 Combination of strength training and green tea gives elderly more muscle mass 12.10.2012 One cup of green tea burns five grams of fat 02.09.2012 Tiny amount of caffeine can burn fat — when combined with tea phenols 27.08.2012 Tea for temporary T boost 24.04.2012 Grow old healthily with green tea 11.03.2012 Tea drinkers have stronger bones 25.02.2012 Lose weight with Pu - Erh tea 17.08.2011 Tea supplement boosts T levels in animal study 30.10.2010 Almost no green tea in green tea sodas 13.10.2010 Drink green tea instead of water — and live longer 24.05.2010 Green tea stackers don't work without exercise 13.05.2010 Metastudy: slimming supplements with green tea do work 27.03.2010 Black tea reduces muscle soreness after training 20.03.2010 Cold brewed white tea contains most antioxidants 04.01.2010 Cup of tea inhibits uptake of mercury from fish 04.12.2009 Polyphenols in juice and tea clear bacteria from your teeth 22.10.2009 Drink three cups of tea a day and add five years to your life 11.09.2009 Bad breath from proteins?

Other hormones play a role in the growth of uterine fibroids as well, including prolactin, parathyroid hormone, insulin growth factor, and pituitary growth hormone.

AustralianSugarDaddy.com maintains a delicate balance between usability and user experience, a factor that has eventually played a significant role in the growth of the site.

In fact, John Ratey, author of A User's Guide to the Brain, calls exercise «Miracle - Gro for the brain» because of its role in stimulating nerve growth factors.

In addition, the investigated 32 summary conclusions on regional impacts do not mention other factors that play an important role, such as the influence of population growth on water shortages.

Researchers in the Perelman School of Medicine at the University of Pennsylvaniahave determined the role of a key growth factor, found in skin cells of limited quantities in humans, which helps hair follicles form and regenerate during the wound healing process.

In consequence of these two benefits, Lu et al. hypothesized that rising atmospheric CO2 is playing a significant role in the observed greening, especially in moisture - limited areas where soil water content is a limiting factor in vegetative growth and function.

Shravya K. Reddy, principal at Pegasys Strategy and Development and Climate Reality's former director of science and solutions, lives in Cape Town and says that while several factors — including relatively rapid population growth, poor planning, and people ignoring previous water restrictions — have all contributed to this crisis, officials» failure to recognize the role that climate change plays in exacerbating drought has made the situation even more dire.

We asked them about their companies, their companies» culture, and their lives, trying to understand how these three factors played a role in the achievement of such impressive growth.