A new mouse model of a genetically - linked type of autism reveals more about
the role of genes in the disorder and the underlying brain changes associated with autism's social and learning problems.
Future studies will need to clarify the exact
role of these genes in intelligence in order to obtain a more complete picture of how genetic differences lead to differences in intelligence.
Inheriting a single X chromosome exposes men to a host of X-linked diseases, such as hemophilia or Duchenne muscular dystrophy, and researchers hope to use the new data to understand more fully
the role of genes in other X-linked conditions.
Published in the journal Science, the new dataset offers fresh insights into the last 500 years of marriage and migration in Europe and North America, and
the role of genes in longevity.
Future studies will investigate
the role of these genes in the underlying biology of Fuchs dystrophy.
It would be tough to figure out
the roles of genes in two different people.
«We were studying
the role of these genes in the development of the vasculature of the kidney,» she recalled.
Current wisdom on
the role of genes in malignancy may not explain some features of cancer, but stepping back to look at the bigger picture inside cells reveals a view that just might
Experiments can then shed light on
the role of the genes in development, aging and disease.
At Cleveland Clinic, Delos Cosgrove, MD, CEO, with the Genomic Medicine Institute and the Education Institute, will inaugurate a Cleveland Clinic - wide genetics education campaign to highlight
the role of genes in health on August 1, 2008, at 7:30 A.M. in Bunts Auditorium.
However, the exact
roles of these genes in the normal state have remained unknown, as genetic knockout of these genes is lethal.
A mutation provides a «way in'to understanding
the role of the gene in normal development.
In the light of a review detailing
the role of these genes in the cell shape changes leading to invagination, and of recent findings showing the expression of twist as mechanically sensitive, we suggest that the expression of twist in the mesoderm could alternatively be maintained by mechanical strains developed during mesoderm invagination.
Critical to ethical review is a cost / benefit analysis; the welfare cost to the animals must be balanced by the benefit of knowledge gained into gene function and
the role of genes in human health and disease.
An elderly man with phenotypic DS and partial trisomy of chromosome 21 (PT21) lacked triplication of APP affording an opportunity to study
the role of this gene in the pathogenesis of dementia.
Animal research that looks at genetically modified mice models is a popular way to understand
the role of genes in schizophrenia.
To examine
the role of these genes in other breeds, Kim needed a standard way of assessing athleticism.
For some developmental and neursocience focused professors, this type of question raises the issue about to the central
role of genes in how we grow.
Not exact matches
In other words, these four genes likely play a key role in the biology of the disorde
In other words, these four
genes likely play a key
role in the biology of the disorde
in the biology
of the disorder.
Athletigen's process involves taking a sample
of an athlete's saliva and subjecting it to genotyping analysis to search for 850,000 different
gene variants that may play a
role in the formation
of athletic traits.
June 19, 2013 — A Cornell University study offers further proof that the divergence
of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that play
roles in turning
genes on and off.
The happenings we know a lot about, thanks to evolutionary biology, particularly
of the last four decades, are the
roles of mutation, recombination
of genes in sexual reproduction resulting
in a great diversity
of gene arrangements, and natural selection.
Speaking about the film recently
in Los Angeles, Cera — who
in this film, takes some refreshingly bold steps away from his usual one - note nerd persona — and co - writer / director Edgar Wright (who also did the zany cult classics Shaun
of the Dead and Hot Fuzz) discussed the meaning
of the film, the stretching Cera had to go through for the
role, and the way
in which the film's hyperkinetic action sequences are really just the same as the dance scenes
in Grease or a
Gene Kelly movie.
To ensure the reestablishment and proliferation
of this magnificent beast
in today's American society, Dr. King has taken an active
role in widening the bison's
gene pool by selecting only gold and silver champion bison to start the herd that became Carolina Bison.
The advent
of rice varieties bearing
genes with resistance to the disease has changed the perception about the disease: the incorporation
of host - plant resistance
genes in rice varieties, their adoption and deployment
in the world's main rice - producing environments is probably one
of the most significant evidences
of the
role of plant pathology
in agricultural development.
Because epigenetics is the real driver
of your health status, and diet plays a major
role in gene expression (aka epigenetics), at least
in this post's animal study!
Sirs: I think you tended to underemphasize the
role of Gene Mauch
in both the rise and the complete collapse
of the team
in 1964.
Some researchers have looked into what
role genes might have
in our tendency to cheat, like last year's study on a certain variant
of the dopamine
gene DRD4 — and dopamine is the force behind our sexual drives, survival needs and pair - bonding behaviors.
The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its
role in gene expression — so it can be expected that Nestle will use the strategy
of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily
in epigentics research).
Following this
in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to play a key
role in the regulation
of gene expression.
Suspended corrections officer
Gene Palmer was arraigned
in Clinton County Court Wednesday on charges related to his
role in the escape
of Richard Matt and David Sweat from the Clinton Correctional Facility last June.
«I would say he... played a significant
role in the restoration
of service,» said
Gene Russianoff, staff attorney at the Straphangers Campaign.
The epigenetic impairments reflect changes that increase accessibility
of chromatin, a process that enhances
gene transcription, suggesting the impairments play an important
role in addiction behavior.
It may be that some versions
of the
gene also play a
role in deafness caused by environmental conditions, creating a predisposition to hearing loss.
Together, these experiments show that the PERIOD3
gene likely plays a key
role in regulating the sleep - wake cycle, influencing mood and regulating the relationship between depression and seasonal changes
in light availability, the team reports today
in the Proceedings
of the National Academy
of Sciences.
Variants
in the
gene called Telomerase Reverse Transcriptase (TERT) on chromosome 5 that were associated with older IEAA were also associated with longer telomeres indicating a critical
role for TERT
in regulating the epigenetic clock,
in addition to its established
role of compensating for cell replication - dependent telomere shortening.
Ten sets
of bacterial
genes have similar, newly discovered defense
roles, researchers report online January 25
in Science.
A new meta - analysis suggests that low expression levels
of 10 related
gene sets responsible for mitochondrial machinery play an important
role in this disorder — all previously unlinked to Parkinson's.
When looking for
genes that might play important
roles in the metabolism
of healthy and cancerous liver cells, Wang and his colleagues became interested
in a
gene called SLC13A5, which produces a protein that transports citrate into cells.
If this
gene plays a
role in energy homeostasis and energy balance
in the context
of obesity, Wang reasoned, perhaps it could play a
role in the energy requirements
of liver cancer cells.
In this special section of Science, expert contributors retrace the long and tortuous path leading to the mapping and identification of the BRCA1 gene; discuss the ways in which BRCA mutation status has been integrated into the clinical management of patients in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activit
In this special section
of Science, expert contributors retrace the long and tortuous path leading to the mapping and identification
of the BRCA1
gene; discuss the ways
in which BRCA mutation status has been integrated into the clinical management of patients in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activit
in which BRCA mutation status has been integrated into the clinical management
of patients
in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activit
in high - risk families; and highlight the
role of the BRCA proteins
in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activit
in preserving the structural and numerical integrity
of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activity.
Genes encoding ribosomal proteins, DNA replication and repair machinery, oxidative stress, and purine biosynthesis were differentially expressed
in Wolbachia during the development
of B. malayi female worms, suggesting a
role of the bacteria
in worm reproduction.
1) That while it's possible that
genes may play some
role in explaining these differences, much
of it comes down to culture, environment, and the fact that the questions on IQ tests are all written by graduate students from Connecticut and begin, «Teddy leaves Sag Harbor on the brunchtime jitney...»
To probe this
gene's
role in brain development, Greenough's collaborators at the University
of Amsterdam and at Erasmus University
in Rotterdam, the Netherlands, knocked out the
gene in mice.
Most
of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task
of studying the
role of a transcription factor (
gene - expression regulator), NF B (nuclear factor kappa B),
in cancer metastasis.
While most
of biology and medicine focus on the key
roles genes and chemicals play
in the formation and control
of living systems, the spatial arrangement
of the components that make up those systems and the physical forces they experience are being increasingly recognized as equally important.
As might be expected
of an autoimmune disease, where the immune system turns on healthy tissue, all the
genes play a
role in controlling the growth and multiplication
of cells
in the immune system.
The FOXP2
gene is thought to have played a
role in the evolution
of the human brain and the development
of language.
But look much closer, at a genetic level, and you will find that many
of the
genes seen
in these flies are also present — and play similar
roles —
in humans.
His team, as well as independent groups based
in the UK, the US and Iceland, uncovered this
gene's
role by comparing genome - wide scans
of thousands
of women with their age at menarche.