Sentences with phrase «roles in cancer development»

The scientific goal of the Cancer Biology Program is to identify novel genomic and genetic alterations that play causal roles in cancer development and to study genes, proteins, and signaling pathways that mediate the altered phenotypes of cancer cells.

«These discoveries illustrate that lncRNAs can play important roles in cancer development and may be useful targets for cancer prevention, detection and treatment.»

NF - kB plays important roles in cancer development, and it is regarded as one of the most important targets for cancer therapy.

Background: Diet and nutrients play an important role in cancer development and progress; a healthy dietary pattern has been found to be associated with several types of cancer.

While they said it's too early to tell if the bacterial differences play a role in cancer development, researchers said their proof - of - concept study is a step needed to answer that question.

• Vitamin D: There's overwhelming evidence pointing to the fact that vitamin D deficiency plays a crucial role in cancer development.

It is of huge importance to avoid the smoke point because it produces free radicals (they have an important role in cancer development) and toxic fumes.

Whole grains also contain antioxidants that may help protect against oxidative damage, which may play a role in cancer development.

Not exact matches

The largest prospective nutrition study ever published suggests animal fat may play a role in the development of pancreatic cancer.

According to the University of Maryland Medical Center polyunsaturated fatty acids (PUFAs)-- also known as omega - 3 fatty acids — play a crucial role in human brain function, as well as normal growth and development, with research showing that they can also reduce inflammation in addition to helping lower the risk of chronic diseases such as heart disease, cancer, and arthritis.

One study took a close look at the role of bacterial microflora in the gut and the occurrence of colon carcinogenesis, or cancer development.

Because oxidative stress is known to play a role in the development of some cancers, and pumpkin seeds are unique in their composition of antioxidant nutrients, it's not surprising to find some preliminary evidence of decreased cancer risk in association with pumpkin seed intake.

Through CBR ®, we also help families to preserve newborn stem cells, which are used today in transplant medicine for certain cancers and blood, immune and metabolic disorders, and have the potential to play a valuable role in the ongoing development of regenerative medicine.

UVB is mostly associated with sunburns and can also play a role in the development of skin cancers and the aging of the skin.

The antibacterial agent is found in products like soap, toothpaste and shampoo, but evidence suggests it plays a role in the development of cancer.

«Cancer Research UK scientists first discovered abiraterone and subsequently played a key role in its development, including funding the first clinical trials.

This suggests that migration of mitochondrial DNA into the nuclear genome plays an important role in development of cancer, say corresponding authors Hemant K. Tiwari, Ph.D., and Keshav K. Singh, Ph.D..

«As scientists, we have focused a good deal of attention on understanding the role of stem cells in the development of cancers, but there hasn't been a focus on mature cells,» said senior investigator Jason C. Mills, MD, PhD, a professor of medicine in the Division of Gastroenterology.

A study published this week in PLOS Medicine suggests that epigenetic modification of the HAND2 gene plays a critical role in the development of endometrial cancer.

It is believed that epigenetics play a huge role in the development and progression of cancer.

BUSM researchers also discussed in Genetics & Epigenetics (May 2014) how epigenetic modifications play a role in the development of diseases including cancer, cardiovascular, metabolic, neurologic and pulmonary disorders.

Now, Salk scientists have developed a highly sensitive, new method that enables them to detect fleeting protein interactions that play critical roles in the development of many diseases including cancer.

He says it's also important to understand the protein's biological role in cellular signaling and normal animal development as well as to consolidate its role in human cancer development, progression and drug - resistance.

Enzymes that chemically modify DNA, known as DNA methyltranferases, play critical roles in regulating gene expression during development, but their role in cancer formation is less clear.

«Considering that frequent amplification of MET accounts for resistance to therapies now in development and to poor prognosis, not only in ovarian cancer but in other cancers too, our findings pinpoint an important new signaling hub, involving the role of FER in MET activation.

However, the role of bacteria in CCA development has not been previously established, despite their relatively well - characterised involvement in colon and gastric (GI tract) cancers.

Moving forward, the team is looking deeper into the role of the ZBTB48 protein in both cancer development and ageing.

Many genes that are involved in the growth and development of embryos or adult stem cells also play roles in cancer, Resar adds.

Investigators found that NPTX2 was expressed in all stages of kidney cancer, especially metastasis, which suggests it plays an important role in tumor development and progression.

They can stop the production of certain proteins and might play roles in cancer and early development.

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer.

Hh also plays many roles in embryonic development, adult homeostasis, birth defects, and cancer.

Dr. Ella Evron and Dr. Ayelet Avraham of the TAU - affiliated Assaf Harofeh Medical Center, together with Prof. Saraswati Sukumar of Johns Hopkins, have found that «gene regulation,» the process that shuts off certain parts of a cell's DNA code or blueprint in healthy breast tissue cells, may also play a critical role in the development of breast cancer.

«Two classes of GGAA - microsatellites in a Ewing sarcoma context: Characterization of GGAA - microsatellites provides insight in the role of noncoding DNA in cancer susceptibility and therapeutic development.»

B - raf gene mutations have known roles in the development of many human cancers including melanoma, lung and thyroid cancer.

She is investigating the role of glycosylated molecules in tumor progression and metastasis, tissue - and species - specific expression of lectin receptors that play a role in regulating host innate immune responses and inflammation, and the immunological mechanisms underlying chronic inflammation and cancer development.

miR - 184 is known to suppress tumor development by regulating a variety of genes involved in cancer growth, while SND1 has been shown to play a significant role in the development of breast, colon, prostate and liver cancers.

Over 2,000 miRNAs are present in human cells, playing various crucial roles in development, cell differentiation, cell division, cell death, and cancer development.

The role of Apelin and Elabela in establishing the circulatory system makes them potential targets in future development of therapeutic applications for illnesses ranging from the various cancers, and cardiovascular diseases, to even metabolic diseases such as diabetes.

While it has been widely accepted that this pathogen plays a role in the development of gastric cancer, these results represent an approach that can reveal a causality between a particular bacterial infection and the development of cancer in humans.

The SH2 domain - containing proteins play important roles in various physiological processes and are involved in cancer development.

Near - death experiences may play a role in embryo development and help cancer cells that survive chemotherapy spread throughout the body, Denise Montell, a cell biologist at the University of California, Santa Barbara, reported December 6 at the annual meeting of the American...

Kyung - Chul Choi and colleagues note that hormonal imbalances seem to play a role in the development of breast cancer.

«We have indications that our discovery constitutes a fundamental principle in the development of tumors and plays an essential role in other cancers.

The adhesive properties of cancer cells play a key role in the formation and development of a tumour.

They have become a valuable resource for biologists, enabling momentous scientific breakthroughs including the development of the polio vaccine the Nobel Prize winning studies defining the role of telomerase in aging, and research on the causative role of human papillomavirus (HPV) in some types of cervical cancer.

Research findings indicate that abnormal CaSR function and / or abundance play a significant role in the development or progression of several non-communicable diseases (or NCDs) such as Alzheimer's disease, cardiovascular diseases, diabetes, cancer, and degenerative muscle loss.

They also play important roles in cell migration, regeneration, neurodegenerative diseases and the development of cancer.

What's really impressive about Babar's accomplishment is that he did the work for both papers — one on the role of a population of stem cells in lung cancer development (published in Cell) the other on gene expression in group A Streptococcus (published in PNAS)-- as a participant in summer undergraduate research programs.

While Rac1 has been shown to play an important role in lung cancer, its role in lung development had not yet been investigated.