Biologically, hypermethylation often silences genes that keep
runaway cell growth in check, and its appearance in the DNA code of breast cancer - related genes shed into the blood may indicate that a patient's cancer growth is increasing and the disease has worsened.
That process is important to cancer researchers, who hope to discover better ways to slow down or stop
runaway cell growth, she explains.
Not exact matches
Cancer
cells have
runaway growth, so the researchers thought the compound might inhibit those
cells.
The
runaway replication of cancer
cells can also traced to genetic causes — mutations that remove the normal controls on
cell growth.
In this study, the researchers found that macrophages from mice lacking Smurf1 were unable to attach the death - tagging protein ubiquitin to intracellular bacteria, resulting in a failure of the autophagy pathway and
runaway growth of the bacteria inside the
cells.
Runaway cell proliferation is driven by accelerators, or oncogenes, that are stuck on go — in collusion with broken brakes, or tumor suppressors, that can't control a tumor's pedal - to - the - metal
growth.