Sentences with phrase «ryanodine receptor»

Dihydropyridine receptors actively control gating of ryanodine receptors in resting mouse skeletal muscle fibres
Functional ryanodine receptors are expressed by human microglia and THP - 1 cells: their possible involvement in modulation of neurotoxicity.
Instead, following exposure to chemotherapy, GSTO1 binds to a protein called the ryanodine receptor 1, or RYR1, that triggers the release of calcium, which causes a chain reaction that transforms ordinary breast cancer cells into cancer stem cells.
In particular, the potential role of the sarcoplasmic reticulum Ca2 + release channel, the ryanodine receptor type 1, will be discussed.
Abstract Type 1 ryanodine receptor (RyR1) is preferentially expressed in skeletal muscle, and mutations in the gene have been associated with malignant hyperthermia, a pharmacogenetic disease, and with several congenital myopathies, including central core disease, multiminicore disease, centronuclear myopathy, congenital fibre type disproportion.
This in turns gates open the Ca2 + + release channel (type 1 ryanodine receptor, RYR1) in the adjacent sarcoplasmic reticulum (SR) membrane, through direct protein - protein interactions.
Jun. 21, 2016 — Sidney Fleischer, a renowned molecular biologist famous internationally for his work on calcium and the discovery of the ryanodine receptor, was remembered as a «true giant» in his field who worked along with his wife to advance the field of cell signaling.
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