After consuming the U.S. Food and Drug Administration's maximum dose of
saccharin over a period of five days, four of the seven subjects showed a reduced glucose response in addition to an abrupt change in their gut microbes.
In addition, there is evidence that artificial sweeteners may also be addictive: in one study rats chose
saccharin over cocaine as a reward.
Not exact matches
Individuals reported their diet
over the past 24 hours and were categorized as consumers of artificial sweeteners (aspartame or
saccharin), or high or low consumers of natural sugars (sugar or fructose).
Controversy
over saccharin and cyclamate as artificial sweeteners still exists but aspartame and acesulfame are used extensively in many foods in the United States.
Studies suggest that artificial sweeteners like
saccharin (Sweet»N Low, SugarTwin), aspartame (NutraSweet, Equal), and sucralose (Splenda) trick the brain into forgetting that sweetness means extra calories, making people more likely to
over do it on sweet treats.