The next step is to see if the process works and is
safe in human cells.
Not exact matches
«We've been hearing about their potential for more than a decade, but the results have always been
in mice and rats, and no one has shown they're
safe or effective
in humans long term,» says Robert Lanza of Advanced
Cell Technology in Marlborough, Massachusetts, the company that carried out the stem cell intervent
Cell Technology
in Marlborough, Massachusetts, the company that carried out the stem
cell intervent
cell intervention.
Researchers
in optogenetics can control genetically modified brain
cells using light but because of these modifications, the technique is not yet deemed
safe to use
in humans.
«Further research into the detailed mechanisms underlying ASIS
in naked mole - rats may shed new light on cancer resistance
in the mole - rats and contribute to the generation of non-tumorigenic
human - iPSCs, enabling
safer cell - based therapeutics,» said Kyoko Miura, an assistant professor at Hokkaido University.
Tests
in mice and nonhuman primates had shown TGN1412 to be
safe, but when it was injected into
humans —
in a dose less than 1/500 of what was given to monkeys — it caused a massive release of infection - fighting T
cells that overstimulated the patients» immune systems, resulting
in multiple organ failure.
Neither group saw
cells developing into anything but brain
cells, but more studies will be needed before the technique can be considered
safe to test
in humans.
He and others have recently used gene - editing tools to correct mutations
in human iPS
cells but haven't used the same combination of methods or done the same set of experiments to determine whether the iPS - derived
cells are
safe.
Earlier this year, scientists at University of California, Los Angeles, and Advanced
Cell Technology of Marlborough, Massachusetts, reported
in The Lancet about the
safe and successful use of RPE
cells derived from
human embryonic stem
cells, rather than iPS
cells, to treat a different type of AMD
in a limited number of
human patients.
Allogeneic Mesenchymal Stem
Cells Stimulate Cartilage Regeneration and Are
Safe for Single - Stage Cartilage Repair
in Humans upon Mixture with Recycled Autologous Chondrons.
Targeted Gene Addition to a
Safe Harbor locus
in human CD34 + Hematopoietic Stem
Cells for Correction of X-linked Chronic Granulomatous Disease.
Clearly, researchers are quickly overcoming the hurdles to using iPS
cells in human clinical trials, though issues still remain to be addressed to ensure their
safe use
in regenerative medicine.
Researchers describe how a bacterial infection - based protein delivery strategy can mediate effective and
safe gene editing
in human pluripotent stem
cells.
«
In a report published in the journal Lancet, scientists led by Dr. Robert Lanza, chief scientific officer at Advanced Cell Technology, provide the first evidence that stem cells from human embryos can be a safe and effective source of therapies for two types of eye diseases&raqu
In a report published
in the journal Lancet, scientists led by Dr. Robert Lanza, chief scientific officer at Advanced Cell Technology, provide the first evidence that stem cells from human embryos can be a safe and effective source of therapies for two types of eye diseases&raqu
in the journal Lancet, scientists led by Dr. Robert Lanza, chief scientific officer at Advanced
Cell Technology, provide the first evidence that stem
cells from
human embryos can be a
safe and effective source of therapies for two types of eye diseases»
These same challenges exist for
human allergy suffers, but recently there has been a major breakthrough
in the development of a new,
safe and effective therapy using a monoclonal antibody that specifically binds and neutralizes
human IgE that is responsible for activating inflammation - producing
cells.