«We have shown that our mutants (versions of the bacteria) are
safe vaccine candidates as our detailed analyses showed no sign of damage to bodily tissues in the vaccinated animals.»
«In addition, this platform can be used to develop
safe vaccine candidates for other flaviviruses such as Zika virus, where pregnant women are the target group for vaccination.»
Not exact matches
In a small trial, an injected
candidate vaccine was
safe and stimulated an immune response.
«You certainly can't do a $ 100 million study for every
candidate vaccine that appears
safe and immunogenic,» says Mark Mulligan, a molecular virologist who heads the
vaccine center at Emory University in Atlanta and does human challenges with norovirus and tuberculosis.
Candidate vaccines against Ebola or malaria — one of which recently received an important stamp of approval in Europe — should definitely be used if they are
safe and effective, he says, but they could lead to more virulent pathogens.
In clinical trials, several
candidate H7N9 pandemic influenza
vaccines made from inactivated viruses have been shown to be
safe and to generate an immune response.
The HVTN's mission is to fully characterize the safety, immunogenicity, and efficacy of HIV
vaccine candidates with the goal of developing a
safe, effective
vaccine as rapidly as possible for prevention of HIV infections globally.
In April 2017, Moderna published human data for its mRNA
vaccine technology in Molecular Therapy, which showed that its first prophylactic
vaccine candidate, mRNA - 1440 — an mRNA prophylactic
vaccine against avian H10N8 influenza — induced high levels of immunogenicity and was
safe and well tolerated.
Results from the sporozoite stage
vaccine look promising, the blood - stage
candidate showed to be
safe but will require further development, the transmission blocking
candidate showed to be
safe and immunogenic and the pre-erythrocytic
candidate showed efficacy in UK adults.