Sentences with phrase «safety cell in»

As in other Mercedes models, for a limited period of time, Mercedes will offer a special edition named Edition 1, which could be identified by exclusive design features such as a tridion safety cell in lava orange, combined with bodypanels / body in white on the fortwo and graphite grey on the forfour.

There will also be a special «Edition # 1» launch version of the 2016 Smart ForTwo that features a lava orange tridion safety cell in combination with a white exterior.

Not exact matches

Immune cells modified by CRISPR - Cas9 were inserted into a lung cancer patient at the West China Hospital in Chengdu in the hopes that they'll be able to fight tumors, and 10 people total will receive injections of CRISPR re-engineered cells in order to assess the method's safety.

To wit: in recent years, Japanese jails have added safety bars in cells and begun offering low - sodium meals to accommodate a surge of criminal senior citizens, shoplifting to cope with hard times.

A months - long investigation into President Donald Trump's personal attorney Michael Cohen's business dealings led to this week's searches of Cohen's residence, hotel room, office, safety deposit box and two cell phones, U.S. prosecutors told a judge in a court filing.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Announced a clinical trial collaboration with Pfizer, Inc. (Pfizer) to evaluate the safety and efficacy of the investigational combination of Yescarta and Pfizer's utomilumab, a fully humanized 4 - 1BB agonist monoclonal antibody, in patients with refractory large B - cell lymphoma.

Examples are 9/11 hijackings, The holding back of stem cell research that could save countless human lives, Aids being spread due to religious opposition to the use of condoms, Christians legally fighting this year to teach over 1 million young girls in America that they must always be obedient to men, the eroding of child protection laws in America by Christians, for so called faith based healing alternatives that place children's health and safety at risk, burning of witches, the crusades, The Nazi belief that the Aryans were god's chosen to rule the world, etc... But who cares about evidence in the real world when we have our imaginations and delusions about gods with no evidence of them existing.

The load cell type SLCAD - ST offers extra safety in applications with heavy rollers and increased temperature compensation.

Our materials make innovation design solutions possible in a range of industries including consumer electronics, solar and wind energy, fuel cells, package printing, aerospace, automotive, food safety and industrial applications.

That's a rarity for WWE in the PG era — Hell in a Cell is a match concept from a much bloodier era with less regard for safety.

There are also SMART goals like an end to police cells being used as a place of safety in cases of mental health in children (by 2016) and for adults in all but exceptional circumstances (by the end of the next parliament).

Due to budget restraints, Correction Management found it more feasible to build dormitories and have decreased the power of the officer to lock an inmate in his cell, for the safety and security of the facility.

Around 3:16 p.m during a safety inspection of the Echo Long Housing Unit, a deputy found Berezowski hanging in his cell by his jail - issued orange pants.

Not only were there no adverse effects from the transplanted cells — this was primarily a safety trial — but 10 patients showed marked improvements in vision, and the eyesight in another seven seems to have stabilized.

The production of virus - free iPS cells, albeit from embryonic fibroblasts, addresses a critical safety concern for potential use of iPS cells in regenerative medicine.

But because genes can regulate multiple processes, more work is needed to determine the safety of modifying the cell cycle in such a way.

For example, an MDM2 - targeting drug shrank deep - tissue fat cell tumors in just one out of 20 patients in a phase I safety trial, published in 2012.

First, the cells are grown in defined supplements without animal products such as bovine serum, enhancing the clinical safety for the muscle stem cells.

In this pilot study to test the safety of putting iPS - derived cells into humans, the six are all receiving a graft of new retinal pigment epithelial cells, which serve to maintain the eye's light - sensing cells.

Northfield Laboratories, Inc., in Evanston, Ill., has been conducting clinical trials for its oxygen - carrying red blood cell substitute, PolyHeme, but in May said the product failed to meet the primary goals of mortality and safety in an important phase III study.

This allowed him to screen the compounds in his lab at the university using much lower BLS - 2 safety standards, to see if they inhibited viral entry into the cell.

In preliminary safety tests, the researchers found no harmful effects in four types of human cells, or in ratIn preliminary safety tests, the researchers found no harmful effects in four types of human cells, or in ratin four types of human cells, or in ratin rats.

Regulations already in place in the European Union insist that stem cell therapies follow the same safety and efficacy rules as pharmaceuticals.

However, in the wake of fatalities from gene therapy and other technologies, as well as the potential for cancers associated with stem cell transplants, governments are understandably nervous about safety issues — not to mention the ethical maze of tinkering with fledgling life.

Omer, Tzannou and their colleagues conducted a clinical trial to determine the safety and effectiveness of pre-prepared virus - specific cells to treat five viral infections simultaneously in patients who had received a hematopoietic stem cells transplant.

Despite a lack of rigorous clinical trials to test safety or efficacy, a ban of the treatment by health authorities, and a lack of peer review by the scientific community, the privately funded Stamina Foundation has been using cultured mesenchymal stem cells that have been exposed to putative conditions that favour neuronal differentiation to treat different diseases in severely or terminally ill patients.

The finding, published in Nature Cell Biology, shows that once disrupted, it takes time for the inflammatory loop to reestablish, providing proof - of - principal that intermittent dosing could provide a way to reap the benefits of rapamycin, an FDA - approved drug that extends lifespan and healthspan in mice, while lessening safety issues associated with its use.

Apart from patient testimonials and a few preliminary studies in tumor cell lines and in mice, critics say, there is no evidence of the safety or efficacy of the compound, popularly known as the «cancer pill» or «fosfo.»

The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.

According to Spradling, these cells «likely arise by dedifferentiation in culture,» and «the same safety and reliability concerns would apply as to any laboratory - generated cell type that lacks a normal counterpart» in the body.

«Our study addressed an important safety issue — whether cancer cells that might be present in testicular tissue samples can survive the process to replicate the sperm - producing stem cells,» said lead author Hooman Sadri - Ardekani, M.D., Ph.D., an instructor in urology and regenerative medicine at Wake Forest Baptist Medical Center.

A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the first to test the safety of an embryonic stem cell therapy for people of Asian descent.

«First embryonic stem cell therapy safety trial in Asian patients.»

As an example of the aqueous zinc battery's power and safety, Fei Wang, a jointly appointed postdoctoral associate at UMD's Clark School and ARL, and first author of the paper, cites the numerous battery fire incidents in cell phones, laptops and electric cars highlighted in recent media coverage.

But the summit's organizers concluded that actually trying to produce a human pregnancy from such modified germ cells or embryos, either through in vitro fertilization (IVF) with the sperm or eggs or the implantation of an embryo, is currently «irresponsible» because of ongoing safety concerns and a lack of societal consensus.

Last week, the U.S. Food and Drug Administration gave Geron permission to conduct a safety test of embryonic stem cells in a handful of patients with a recent spinal cord injury.

A team led by principal investigator Donald M. O'Rourke, MD, an associate professor of Neurosurgery at Penn, and Marcela Maus, MD, PhD, showed that CART - EGFRvIII cells had an acceptable safety profile, crossed the blood - brain barrier, infiltrated the tumor, and prompted an immune response, resulting in reduction of the EGFRvIII tumor antigen in GBM cells.

The Food and Drug Administration approved the trial in January 2009 but put it on hold last September because of safety concerns after lab animals injected with stem cells developed small cysts at the injury site.

If these preclinical studies are successful, the researchers plan to further develop their CAR T cell therapy and test its safety and efficacy for different types of metastatic cancer in upcoming clinical trials.

Preliminary safety testing on cells grown in the laboratory showed the drugs were not toxic to mammalian cells because they only inhibit the bacterial ribosomes and not mammalian ribosomes.

As an additional safety feature, the researchers introduced two mutations that weakened the virus's ability to combat the cell's defenses against infection, reasoning that the mutated virus still would be able to grow in tumor cells — which have a poor antiviral defense system — but would be eliminated quickly in healthy cells with a robust antiviral response.

In a new study scheduled for publication in The Journal of Pediatrics, researchers evaluated the safety and feasibility of using stem cell therapies on very preterm infants to prevent or treat BPIn a new study scheduled for publication in The Journal of Pediatrics, researchers evaluated the safety and feasibility of using stem cell therapies on very preterm infants to prevent or treat BPin The Journal of Pediatrics, researchers evaluated the safety and feasibility of using stem cell therapies on very preterm infants to prevent or treat BPD.

Kaelin's group reasoned that if they could disable this remaining safety check in cancer cells, then E2F would become abundant enough to provoke a spiral of programmed cell death.

By 2007, the drug had been tested on cells and in a phase I clinical safety trial in healthy volunteers.

«Cell phone bans have reduced cell phone use by drivers, but the perplexing thing is that they haven't reduced crashes,» says Russ Rader, a spokesperson for the Insurance Institute for Highway Safety in Arlington, Virginia, who was not involved in the new stCell phone bans have reduced cell phone use by drivers, but the perplexing thing is that they haven't reduced crashes,» says Russ Rader, a spokesperson for the Insurance Institute for Highway Safety in Arlington, Virginia, who was not involved in the new stcell phone use by drivers, but the perplexing thing is that they haven't reduced crashes,» says Russ Rader, a spokesperson for the Insurance Institute for Highway Safety in Arlington, Virginia, who was not involved in the new study.

Unlike for ccr5, there are no known humans with loss of function cxcr4 mutations that would provide insight into the safety and viability of cxcr4 disruption in mature CD4 + T cells.

In contrast, the safety record of hematopoietic stem cell gene therapy is less clear, with a significant frequency of gene - therapy induced oncogenesis or clonal outgrowth reported in several hematopoietic stem cell trials [56], [57In contrast, the safety record of hematopoietic stem cell gene therapy is less clear, with a significant frequency of gene - therapy induced oncogenesis or clonal outgrowth reported in several hematopoietic stem cell trials [56], [57in several hematopoietic stem cell trials [56], [57].

«We need to develop specific tools to study chemical toxicity in human reproductive cells; this will allow us to accurately assess safety thresholds for different compounds, and re-evaluate the acceptible daily intake levels to protect human health for some of them» said Professor Habert.

The study, conducted in Arizona, was designed to evaluate the safety of injecting muscle - derived stem cells directly into the hearts of patients with congestive heart failure, using a 3 - dimensional guided catheter system.