Sentences with phrase «safety cell of»

Not exact matches

Immune cells modified by CRISPR - Cas9 were inserted into a lung cancer patient at the West China Hospital in Chengdu in the hopes that they'll be able to fight tumors, and 10 people total will receive injections of CRISPR re-engineered cells in order to assess the method's safety.

To wit: in recent years, Japanese jails have added safety bars in cells and begun offering low - sodium meals to accommodate a surge of criminal senior citizens, shoplifting to cope with hard times.

A months - long investigation into President Donald Trump's personal attorney Michael Cohen's business dealings led to this week's searches of Cohen's residence, hotel room, office, safety deposit box and two cell phones, U.S. prosecutors told a judge in a court filing.

• Luxcel Biosciences, an Ireland - based company that had developed technology to monitor the growth and viability of cells for pharmaceutical safety, was acquired by Aglient Technologies, according to The Irish Times.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Announced a clinical trial collaboration with Pfizer, Inc. (Pfizer) to evaluate the safety and efficacy of the investigational combination of Yescarta and Pfizer's utomilumab, a fully humanized 4 - 1BB agonist monoclonal antibody, in patients with refractory large B - cell lymphoma.

Also, they have chosen a cheap populist theme, attacking cell phone, bank and credit - card charges instead of hammering the Conservatives on their dangerous, right - wing deregulation agenda — even though people are still dying as a result of Harper's «self - regulation» changes to food safety.

No. 4: CAR - T takes a backseat Research into chimeric antigen receptor T - cell (CAR - T) therapy has captured the attention of investors over the past two years, but safety risks could emerge as trial sizes increase, and that could help shift attention to other promising anti-cancer approaches, including NantKwest's (NASDAQ: NK) natural killer cell approach and soon - to - IPO Editas» CRISPR / Cas approach.

Examples are 9/11 hijackings, The holding back of stem cell research that could save countless human lives, Aids being spread due to religious opposition to the use of condoms, Christians legally fighting this year to teach over 1 million young girls in America that they must always be obedient to men, the eroding of child protection laws in America by Christians, for so called faith based healing alternatives that place children's health and safety at risk, burning of witches, the crusades, The Nazi belief that the Aryans were god's chosen to rule the world, etc... But who cares about evidence in the real world when we have our imaginations and delusions about gods with no evidence of them existing.

Duly reverential, the panel satisfied itself with simply listing all the research possibilities, including the improvement and increased safety of IVF, the creation of cell lines that might someday be useful for bone marrow transplantation, repair of spinal cord injuries, skin replacement and, naturally, the hint of a greater understanding of cancer.»

The feature - rich Easypack ® Quantum ™ XTW offers high productivity, ease - of - use, safety, superior ergonomics, paper - loading ease, as well as, flexible design which enables customized work cell options.

Our materials make innovation design solutions possible in a range of industries including consumer electronics, solar and wind energy, fuel cells, package printing, aerospace, automotive, food safety and industrial applications.

Some of their safety features include Safe Cell Technology, Integrated Steel Bars and Energy Absorbing Versa - Tether and with the Marathon G4 Britax USA have also incorporated Side Impact Protection.

While some parents may fear giving their child a cell phone opens the door to danger, such as the child contacting undesirable people without the parent knowing or a teenager texting her boyfriend at all hours of the day and night, other parents view the cell phone as a safety tool.

Equipped with a Safe Cell Impact Protection, this car seat is built with a number of safety features including an impact absorbing base, harness and tether as well as an impact stabilizing frame.

Safe cell impact protection is an integrated system of safety components that work together to protect your child beyond the federal safety standards, this includes our impact absorbing base and complete side impact protection plus

It features safe cell impact protection which is and integrated of safety components that ensure protection for your child.

The National Transportation Safety Board is seeking to obtain cell phone records of the teenager and the engineer, said Kitty Higgins, a member of the board dispatched to the scene.

There are also SMART goals like an end to police cells being used as a place of safety in cases of mental health in children (by 2016) and for adults in all but exceptional circumstances (by the end of the next parliament).

«The select committee proposes changing the law so that police cells can no longer be used as a «place of safety», but that alone won't fix these problems.

It also proposes amending the Mental Health Act 1983, so that police cells are no longer stated as a place of safety for those detained under section 136.

Due to budget restraints, Correction Management found it more feasible to build dormitories and have decreased the power of the officer to lock an inmate in his cell, for the safety and security of the facility.

Around 3:16 p.m during a safety inspection of the Echo Long Housing Unit, a deputy found Berezowski hanging in his cell by his jail - issued orange pants.

«It has the magic of both great antibody response and inducing a strong, strong T cell response that will be a safety net — so if a virus breaks through the first line of defense, you will have T cells to make sure you don't get very sick,» Sullivan says.

The clinical trial is designed to assess safety and activity of escalating doses of the special cells (AST - OPC1) for individuals with a complete cervical spinal cord injury.

The production of virus - free iPS cells, albeit from embryonic fibroblasts, addresses a critical safety concern for potential use of iPS cells in regenerative medicine.

While Nagy can get piggyBac to jump back out of his iPS cells, regulatory authorities considering the safety of experimental therapies are likely to remain nervous about cells that have been genetically manipulated.

ACT is now performing early - phase clinical trials testing the safety of implanting retinal cells derived from human ES cells into the eye to treat certain types of blindness.

But because genes can regulate multiple processes, more work is needed to determine the safety of modifying the cell cycle in such a way.

Bringing back the whole - cell vaccine is unlikely, Edwards and Offit say, because of the safety concerns, but Edwards suggests it might be possible to modify a new whole - cell vaccine that's less reactive or to add antigens to the acellular vaccine.

«Cell phone conversations hinder child pedestrian crossing abilities: Cellphone safety should be part of back - to - school preparation.»

«We've long known that NF - kB promotes cancer development by subverting apoptosis, an internal safety mechanism that otherwise would cause cancer cells to self - destruct,» says principal investigator Denis Guttridge, PhD, professor of molecular virology, immunology and medical genetics and of molecular and cellular biochemistry.

For example, an MDM2 - targeting drug shrank deep - tissue fat cell tumors in just one out of 20 patients in a phase I safety trial, published in 2012.

To address this challenge, our research group is using nanoparticles not only to deliver more chemotherapy drugs to the target site within cancer cells, but also to compromise the function of the efflux pumps and thereby significantly improve safety and efficacy of cancer therapy.»

The scientists have discovered that the colon has a safety mechanism to prevent the self - renewal of adenoma stem cells.

There have also been safety concerns confronting all hESC studies, including worries that the embryonic stem cells could proliferate out of control.

In this pilot study to test the safety of putting iPS - derived cells into humans, the six are all receiving a graft of new retinal pigment epithelial cells, which serve to maintain the eye's light - sensing cells.

Northfield Laboratories, Inc., in Evanston, Ill., has been conducting clinical trials for its oxygen - carrying red blood cell substitute, PolyHeme, but in May said the product failed to meet the primary goals of mortality and safety in an important phase III study.

«The global stem - cell and regenerative medicine community will be awaiting the results of this safety trial with much anticipation.»

A second randomized trial on the use of the sun - safety mobile app Solar Cell showed some improvement and was associated with greater sun protection, according to an article published online by JAMA Dermatology.

In preliminary safety tests, the researchers found no harmful effects in four types of human cells, or in rats.

Moderna is also doing animal safety tests of a personalized cancer vaccine that would code for immune - activating proteins unique to a person's cancer cells, based on genetic sequencing of their tumor.

The authors suggest the NFL and other sports leagues should review the procedures for stem cell treatment to determine how best to support, evaluate and possibly regulate stem cell treatments to ensure the safety of their players and their followers.

However, in the wake of fatalities from gene therapy and other technologies, as well as the potential for cancers associated with stem cell transplants, governments are understandably nervous about safety issues — not to mention the ethical maze of tinkering with fledgling life.

Omer, Tzannou and their colleagues conducted a clinical trial to determine the safety and effectiveness of pre-prepared virus - specific cells to treat five viral infections simultaneously in patients who had received a hematopoietic stem cells transplant.

Despite a lack of rigorous clinical trials to test safety or efficacy, a ban of the treatment by health authorities, and a lack of peer review by the scientific community, the privately funded Stamina Foundation has been using cultured mesenchymal stem cells that have been exposed to putative conditions that favour neuronal differentiation to treat different diseases in severely or terminally ill patients.

The finding, published in Nature Cell Biology, shows that once disrupted, it takes time for the inflammatory loop to reestablish, providing proof - of - principal that intermittent dosing could provide a way to reap the benefits of rapamycin, an FDA - approved drug that extends lifespan and healthspan in mice, while lessening safety issues associated with its use.

Apart from patient testimonials and a few preliminary studies in tumor cell lines and in mice, critics say, there is no evidence of the safety or efficacy of the compound, popularly known as the «cancer pill» or «fosfo.»

They will examine the safety and feasibility of administering cancer - fighting chimeric antigen receptor (CAR) T cells that have been reprogrammed to target the CD22 protein expressed by some leukemia cells.

Along with improved potency and safety, the system saves time by providing easy, ready - touse RNA reagents that also reduce cell toxicity by avoiding activation of cellular innate immune responses.