Sentences with phrase «safety cell with»

On the safety side of things, the car came standard with Bosch ABS and traction control, central carbon fiber safety cell with a steel and carbon fiber roll bar, and front and rear carbon fiber impact absorbers.

Engine choices include the company's 70 HP (52 kW) plant and the 83 HP (62 kW) unit, and some of the features that make this car a «special edition» include the two - tone colour scheme which combines the red painted tridion safety cell with the rest of the car's exterior which is painted black, plus the 15 - inch alloy wheels also featuring a brilliant black finish.

New edition # 1 package with design features and Lava Orange Tridon safety cell with white body panels, plus optional Sport and Lighting packages

Not exact matches

To wit: in recent years, Japanese jails have added safety bars in cells and begun offering low - sodium meals to accommodate a surge of criminal senior citizens, shoplifting to cope with hard times.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Announced a clinical trial collaboration with Pfizer, Inc. (Pfizer) to evaluate the safety and efficacy of the investigational combination of Yescarta and Pfizer's utomilumab, a fully humanized 4 - 1BB agonist monoclonal antibody, in patients with refractory large B - cell lymphoma.

Examples are 9/11 hijackings, The holding back of stem cell research that could save countless human lives, Aids being spread due to religious opposition to the use of condoms, Christians legally fighting this year to teach over 1 million young girls in America that they must always be obedient to men, the eroding of child protection laws in America by Christians, for so called faith based healing alternatives that place children's health and safety at risk, burning of witches, the crusades, The Nazi belief that the Aryans were god's chosen to rule the world, etc... But who cares about evidence in the real world when we have our imaginations and delusions about gods with no evidence of them existing.

Duly reverential, the panel satisfied itself with simply listing all the research possibilities, including the improvement and increased safety of IVF, the creation of cell lines that might someday be useful for bone marrow transplantation, repair of spinal cord injuries, skin replacement and, naturally, the hint of a greater understanding of cancer.»

The load cell type SLCAD - ST offers extra safety in applications with heavy rollers and increased temperature compensation.

That's a rarity for WWE in the PG era — Hell in a Cell is a match concept from a much bloodier era with less regard for safety.

Some of their safety features include Safe Cell Technology, Integrated Steel Bars and Energy Absorbing Versa - Tether and with the Marathon G4 Britax USA have also incorporated Side Impact Protection.

There is a deluxe parent tray with a place to store your cell phone with a clip for safety.

The EverTrue Elite Mattress is made with open cell, pressure reduction, viscoelastic memory foam for your baby's comfort and safety.

It is built with a Safe Cell Impact Protection that shields your child with safety precautions that go outside the limitations set by the safety standards.

Equipped with a Safe Cell Impact Protection, this car seat is built with a number of safety features including an impact absorbing base, harness and tether as well as an impact stabilizing frame.

Sleep soundly knowing your littlest one is resting on the EverTrue ™ Elite: a crib mattress made with open cell, pressure reduction, viscoelastic memory foam for your baby's comfort and safety.

The clinical trial is designed to assess safety and activity of escalating doses of the special cells (AST - OPC1) for individuals with a complete cervical spinal cord injury.

«The global stem - cell and regenerative medicine community will be awaiting the results of this safety trial with much anticipation.»

A second randomized trial on the use of the sun - safety mobile app Solar Cell showed some improvement and was associated with greater sun protection, according to an article published online by JAMA Dermatology.

However, in the wake of fatalities from gene therapy and other technologies, as well as the potential for cancers associated with stem cell transplants, governments are understandably nervous about safety issues — not to mention the ethical maze of tinkering with fledgling life.

The finding, published in Nature Cell Biology, shows that once disrupted, it takes time for the inflammatory loop to reestablish, providing proof - of - principal that intermittent dosing could provide a way to reap the benefits of rapamycin, an FDA - approved drug that extends lifespan and healthspan in mice, while lessening safety issues associated with its use.

Along with improved potency and safety, the system saves time by providing easy, ready - touse RNA reagents that also reduce cell toxicity by avoiding activation of cellular innate immune responses.

A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the first to test the safety of an embryonic stem cell therapy for people of Asian descent.

But the summit's organizers concluded that actually trying to produce a human pregnancy from such modified germ cells or embryos, either through in vitro fertilization (IVF) with the sperm or eggs or the implantation of an embryo, is currently «irresponsible» because of ongoing safety concerns and a lack of societal consensus.

A clinical trial investigating a treatment for blindness is under way this winter to evaluate the safety and efficacy of replacing diseased eye cells with stem cells.

Last week, the U.S. Food and Drug Administration gave Geron permission to conduct a safety test of embryonic stem cells in a handful of patients with a recent spinal cord injury.

The Food and Drug Administration approved the trial in January 2009 but put it on hold last September because of safety concerns after lab animals injected with stem cells developed small cysts at the injury site.

As an additional safety feature, the researchers introduced two mutations that weakened the virus's ability to combat the cell's defenses against infection, reasoning that the mutated virus still would be able to grow in tumor cells — which have a poor antiviral defense system — but would be eliminated quickly in healthy cells with a robust antiviral response.

Unlike for ccr5, there are no known humans with loss of function cxcr4 mutations that would provide insight into the safety and viability of cxcr4 disruption in mature CD4 + T cells.

In contrast, the safety record of hematopoietic stem cell gene therapy is less clear, with a significant frequency of gene - therapy induced oncogenesis or clonal outgrowth reported in several hematopoietic stem cell trials [56], [57].

The study, conducted in Arizona, was designed to evaluate the safety of injecting muscle - derived stem cells directly into the hearts of patients with congestive heart failure, using a 3 - dimensional guided catheter system.

Several concerns need to be addressed before its use, such as effective delivery and the safety of tinkering with DNA in brain cells.

Under his direction, from 2003 to 2007, the agency brought a new level of commitment to public health, with special emphasis on emerging issues such as bioterrorism and emergency preparedness, as well as health disparities, patient safety and creation of the Illinois Regenerative Medicine Institute to support stem cell research.

An innovative experimental treatment for boosting the effectiveness of stem - cell transplants with umbilical cord blood has a favorable safety profile in long - term animal studies, report scientists from Dana - Farber Cancer Institute, Beth Israel Deaconess Medical Center (BIDMC), and Children's Hospital Boston (CHB).

The Phase I safety trial, funded with a pilot grant from The National Institutes of Health and support from the Notsew Orm Sands Foundation, will enroll nine more patients who have suffered a stroke and can be treated with the stem cell procedure within 24 to 72 hours of initial symptoms.

Our science and technologies have demonstrated the possibility of highly potent antibody and T cell responses while maintaining safety, even with repeated administrations.

The company had initially submitted its request to begin human trials with its RPE cells in November 2009, but has spent the past year addressing the FDA's concerns about the safety of the embryonic stem from which the RPE cells are made.

One of the major parameters was the safety of these agents in the respiratory airways and lung parenchyma, since several of these agents are known to cause adverse effects.23 The main adverse effects observed were cough, transient fever and transient decrease in the respiratory functions after the aerosol administration.8, 19, 20 Moreover; it has been observed that excessive deposition of these agents in one site of the respiratory system can induce non-specific side effects in the form of pulmonary edema as observed with many other drugs.16 These side effects were milder when a premedication with bronchodilators and inhaled corticosteroids were administered.8, 19, 20 Until now no long term trial (> 9 months) has been performed since all patients included in previous studies had stage IV non-small cell lung cancer (NSCLC).

The full paper that this statement is in response to can be found at: Niederberger et al. 2018 Safety and efficacy of immunotherapy with the recombinant B - cell epitope — based grass pollen vaccine BM32.

Many of the concerns relate to safety, in part because the impact of tinkering with cells at that level may not be completely evident for years or even generations, said Debra Mathews, assistant director for science programs at the Berman Institute of Bioethics at Johns Hopkins University.

Two major safety concerns of working with viruses are the potential for generation of replication competent virus, and the potential for oncogenesis (in a host cell) via insertional mutagenesis.

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.

AST - VAC1 (antigen - presenting autologous dendritic cells) is an autologous cancer immunotherapy with promising efficacy and safety data from a Phase 2 study in Acute Myeloid Leukemia (AML).

«Human neurons — derived from reengineered skin cells — could help assess the efficacy and safety of these drugs, thereby reducing risks and resources associated with human trials.»

Since 1995, Dr. Maharaj has been applying his academic experience and performing evidence - based chemotherapy treatment and bone marrow stem cell transplant procedures on a completely outpatient setting, with the main purpose of improving patients» safety by minimizing the risks of mortality associated with hospital - acquired infections and, ultimately, improving quality of life.

With these technologies, we are creating heart cells from skin samples of patients with many cardiovascular diseases, such as heart failure, to test the safety and efficacy of new or existing drugs that treat or prevent the conditWith these technologies, we are creating heart cells from skin samples of patients with many cardiovascular diseases, such as heart failure, to test the safety and efficacy of new or existing drugs that treat or prevent the conditwith many cardiovascular diseases, such as heart failure, to test the safety and efficacy of new or existing drugs that treat or prevent the condition.

A pilot study assessing the safety and feasibility of the transplantation of autologous iPSC - derived retinal pigment epithelium (RPE) cell sheets in patients with exudative (wet - type) age - related macular degeneration was launched in Japan in August 2013.

The routine use of MSC cellular therapy with would benefit from a uniform cell source, with stable phenotype and function as well as providing a solution to potential safety issues.

Japan has taken some steps in this direction, both in establishing the first centre dedicated entirely to hiPSC research, with an emphasis on application, and by publishing a draft of what looks to be the world's first governmental regulations specifically focused on hiPSC - derived cell safety and quality [15].

An additional goal of the partnership is to use patient - derived cells in Organ - Chips to make progress with strategies for personalized drug safety and allow a new approach to augment the prediction of disease or treatment variation between individuals.