Sentences with phrase «said gladstone»
«We hope our human model of ALS will help us to move quickly and effectively to identify promising therapeutic candidates for ALS,» said Gladstone Senior Investigator Steve Finkbeiner, MD, PhD, who is also a professor of neurology and physiology at the University of California, San Francisco, with which Gladstone is affiliated.
https://gladstone.org/
«When we injected GMT into each of the three types of human fibroblasts, nothing happened — they never transformed — so we went back to the drawing board to look for additional genes that would help initiate the transformation,» said Gladstone Staff Scientist Ji - dong Fu, PhD, the study's lead author.
«We are thrilled that Katie was selected from among more than 750 applicants,» said Gladstone President R. Sanders «Sandy» Williams, MD. «Her innovative work has set the standards for computational biology in microbiome research.»
«Leor and Nevan pursue important scientific questions with extraordinary creativity and technological prowess,» said Gladstone president R. Sanders «Sandy» Williams.
«Lundbeck is a truly visionary company with a well - focused strategy for building a pipeline to treat neurological disease,» said Gladstone president R. Sanders Williams, MD. «We are enthusiastic about the potential of this important collaboration.»
«Vegf sets off a signaling cascade that eventually activates a group of proteins, called Mitogen Activated Protein Kinases, or MAPKs,» said Gladstone Staff Scientist Joshua Wythe, PhD, the paper's lead author.
«We detected heightened thrombin activity at specific disease «hot - spots,» regions where neuronal damage developed over time,» said Gladstone Staff Research Scientist Dimitrios Davalos, PhD, associate director of the CIVIR and one of the paper's lead authors.
«Katerina's research is opening new avenues to understanding mechanisms of neuroinflammation, with exciting translatable opportunities,» said Gladstone President R. Sanders «Sandy» Williams, MD. «This new grant will accelerate her progress.
«Gladstone is uniquely qualified to take on this major research, which will fill a critical gap in the understanding of brain function and neurological disease,» said Gladstone president Robert W. Mahley, MD, PhD.
«But whether such neuronal - network disruptions also impair memory was unknown,» said Gladstone Postdoctoral Fellow Pascal Sanchez, PhD, who is the paper's lead author.
«Gladstone lost a wonderful friend and long - time supporter,» said Gladstone President R. Sanders «Sandy» Williams, MD. «One of Bill's many talents was to lead by example — launching great companies, giving generously to important causes, and befriending many.
«The accelerator circuit gives CMV the powerful strategic advantage to outpace immune defense systems,» said Gladstone Staff Scientist Cynthia Bolovan - Fritts, PhD, the paper's other lead author.
«This collaboration has high potential to open new avenues towards effective therapies for neurodegenerative diseases,» said Gladstone President R. Sanders Williams, MD. «Both organizations are committed to meeting this major unmet need.»
It is a huge jump forward from previous genome editing techniques,» said Gladstone Senior Investigator Bruce Conklin, MD, an early adopter of the technology.
«Stem cell biology has become one of the most exciting and promising areas of research, with real impact on how we treat human disease,» said Gladstone President R. Sanders Williams, MD. «With its meetings and journals, ISSCR has developed a significant role in communicating and promoting groundbreaking advances in the field.
«Our studies have investigated and identified the root cause of AIDS — how CD4 T cells die,» said Gladstone Staff Research Investigator Gilad Doitsh, PhD, who is the Nature paper's lead author, along with Nicole Galloway and Xin Geng, PhD.
«Over the course of a person's life, with repeated exposure to bacteria and viruses, these T cells mature and eventually lose a protein called CD28,» said Gladstone Senior Investigator Melanie Ott, senior author of the new study.
«Surprisingly, NFAT didn't appear to play a central role so we went back to the drawing board, exploring other protein families we thought might be involved,» said Gladstone Postdoctoral Fellow Jonathan Chan, PhD, the paper's lead author.
«Our findings could have a significant impact on the treatment of autoimmune diseases, as well as on stem cell and immuno - oncology therapies,» said Gladstone Senior Investigator Sheng Ding, PhD, who is also a professor of pharmaceutical chemistry at the University of California, San Francisco.
«As both a physician and a scientist, Dr. Takahashi embodies the ideal recipient because her work brings cellular reprogramming to patients,» says Gladstone president R. Sanders Williams, MD. «Mr. Ogawa's visionary support of translational stem cell research will help encourage and accelerate the progression of the field.»
Not exact matches
I was very struck and motivated by an article in The Times the day after I was elected leader that said the party that started with Gladstone will end with Farron.
said Elwyn Gladstone, founder of Biggar & Leith.
«We are thrilled to bring Malfy Gin to the U.S. this year through our partnership with Breakthru Beverage Group,» said Biggar & Leith Founder Elwyn Gladstone.
Principal Gary Moriello of Gladstone Elementary School said he doubts news of the price increases will upset parents at his school.
I remember listening to a lecture a few years ago — it might have been Roy Hattersley talking about the shouters at a Gladstone political meeting — and there were people standing 50 yards back from the stage, and then another 50 yards back, relaying what he was saying to people standing behind because there was no method of amplification.
GLADSTONE, N.J. (AP)-- Republican New Jersey Gov. Chris Christie says he'd «smack» Democratic New York Gov. Andrew Cuomo for predicting a «summer of hell» as part of track repairs at the nation's busiest rail station.
«In science, difficult times are inevitable,» says Steven Finkbeiner, associate director and associate investigator at the Gladstone Institute of Neurological Disease and Associate Professor of Neurology and Physiology at the University of California, San Francisco.
That means that Pluto has held onto a lot more of its nitrogen than was thought, says Randy Gladstone, a New Horizons scientist at SWRI.
«If you do this enough times, and deplete the pool of latently infected cells, you could potentially cure patients from infection,» says Eric Verdin, a senior investigator at the Gladstone Institute of Virology and Immunology at the University of California, San Francisco.
«This was strange because it meant that, contrary to what we believed, MYC isn't necessary for cells to reprogram efficiently,» said Tim Rand, MD, PhD, staff scientist at Gladstone and a first author of the study.
«This is probably the first handle we have on what makes the heart young and what makes it old,» says cardiologist Deepak Srivastava of the Gladstone Institute of Cardiovascular Disease in San Francisco, California, who was not involved in the work.
«Although free - floating viruses establish the initial infection, it is the subsequent cell - to - cell spread of HIV that causes massive CD4 T cell death,» says co-first author Nicole Galloway, PhD, a post-doctoral fellow at the Gladstone Institute of Virology and Immunology.
«The fundamental «killing units» of CD4 T cells in lymphoid tissues are other infected cells, not the free virus,» says co-first author Gilad Doitsh, PhD, a staff research investigator at the Gladstone Institute of Virology and Immunology.
«By understanding the gene networks that get disrupted in CAVD, we can pinpoint what we need to fix and find new therapeutics to correct the disease process,» says first author Christina Theodoris, an MD / PhD student at the Gladstone Institutes and UCSF.
«We thought it might be important to look instead at the toxic environment outside the cell, where blood proteins accumulate» said Akassoglou, senior investigator at Gladstone, professor of neurology at UC San Francisco (UCSF), and senior author of a study published by the scientific journal Neuron.
«Historically, studies had found a weak relationship between money and overall well - being,» says Joe Gladstone.
«Our results provide the first evidence that blood promotes T cell responses against the brain,» says first author Jae Kyu Ryu, PhD, a staff research scientist at the Gladstone Institutes.
«Our findings have provided us not only with a new perspective on the role of astrocytes in cognition, but also with an exciting drug target to enhance memory and maybe even stave off memory decline in Alzheimer's disease,» says senior author Lennart Mucke, MD, director of the Gladstone Institute of Neurological Disease and professor of neurology and neuroscience at the University of California, San Francisco.
«It would really be wonderful if tau reduction turned out to be useful not only in Alzheimer's disease, but also in other disabling neurological conditions for which there currently are no effective treatments,» said senior author Lennart Mucke, MD, the director of the Gladstone Institute of Neurological Disease and a professor of Neurology and Neuroscience at the University of California, San Francisco.
«I am especially excited about the improvements we observed in cognitive and behavioral dysfunctions because these abnormalities are particularly hard on the kids — and their parents,» said first author Ania Gheyara, MD, PhD, a staff scientist at Gladstone who is also affiliated with the UCSF Department of Pathology.
«We were very encouraged to see that the transplanted cells sprouted long distances in both directions — a key characteristic of V2a interneurons — and that they started to connect with the relevant host neurons,» said co-author Dylan McCreedy, PhD, a postdoctoral scholar at Gladstone.
«Interneurons can reroute after spinal cord injuries, which makes them a promising therapeutic target,» said senior author Todd McDevitt, PhD, a senior investigator at Gladstone.
«This has been an absolutely fascinating voyage of discovery,» said Dr. Greene, who is also a professor of medicine, microbiology and immunology at the University of California, San Francisco, with which Gladstone is affiliated.
«It's not a ban,» says Warner Greene, an IOM committee member who is director of the Gladstone Institute of Virology and Immunology at the University of California, San Francisco.
When the show had run its course, Gladstone stood silent for a moment, and then said to Faraday: «It is very interesting, Mr Faraday, but what practical worth has it?»
«With few exceptions, our postdocs receive the exact same benefits as everyone else at Gladstone, which includes employer - paid medical, dental, and vision, and also covers eligible dependents or domestic partners,» said John LeViathan, postdoctoral fellows advisor and human resources manager.
«With the mercury, we tried to find something else that would fit [the spectra], but it just does a great job,» Gladstone says.
«Introducing brown fat is an exciting new approach to treating obesity and associated metabolic diseases, such as diabetes,» said study first author Baoming Nie, PhD, a former postdoctoral scholar at Gladstone.
«This identified IFI16 as the DNA sensor, which then sends signals to caspase - 1 and triggers pyroptosis,» says Kathryn M. Monroe, PhD, the Science paper's other lead author, who completed the research while a postdoctoral fellow at Gladstone.
«He did this back - of - the - envelope calculation to make this wild prediction — and it's dead - on, as far as we can tell,» Gladstone says.