Not exact matches
Instead, Dr. Baselga
said researchers and scientists are making strides in what he calls precision medicine, an
emerging approach for
disease treatment and prevention that takes into account individual variability in environment, lifestyle and genes for each person.
Sumner
says that lnc - RNAs are still a rapidly
emerging field, and we are just beginning to learn what they do and their role in
disease.
«While electrical stimulation of the brain is
emerging as potential therapy for a wide range of neurological and psychiatric
diseases, little is known about its effect on memory,»
says Gregory Worrell, M.D., Ph.D., a Mayo Clinic neurologist and senior author of the article.
«It started to become quite evident to me that a research career in infectious
disease epidemiology and mathematical modeling would be a fairly perfect combination of my longstanding interests in math and biology and medicine, as well as my
emerging interest in infectious
disease transmission and public health more generally,» she
says.
But until then, we can not foresee how
disease - spreading organisms move, interact and
emerge due to climate changes, intensified agriculture or urbanization,
says senior - author Professor Carsten Rahbek.
The report
says that preimplantation genetic diagnosis should be allowed in cases where a couple want to have a child, but a pregnancy is likely to lead to a baby with a serious and incurable genetic
disease, including those that first
emerge in adulthood.
«Whether it's an oil well blowout or an
emerging disease, you don't want to get up to speed then,»
said Holt.
«When you have this combination of tremendous global transport of people and goods, changing ecosystems, and changing climate,» Balbus
says, «it raises the possibility of
emerging diseases.»
In other words, she
says, personality constructs
emerging from the basic biology of the brain can be yet another marker that the individual is at risk for TILT, and easier to sensitize to the
disease.
To be better prepared next time, the UK needs a plan that identifies top
emerging disease threats and outlines courses of action, the report
says.
No one know how many birds succumb each year to the wildlife trade since much of the trafficking is illegal, but within Southeast Asia alone, it is likely «in the order of tens of millions,»
says Kelly Edmunds, a researcher at the University of East Anglia in England who investigates the
emerging infectious
diseases amongst bird sellers in Asia and was not involved in the study.
«From other studies ***** we know that epigenetic modifications of the DPP4 gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver
disease emerges,»
says Baumeier.
«Whether we can predict
emerging diseases is a whole other question,» Ford
says, especially as their vectors or risk factors might take time to assess.
«Our models showed Hopi corn could grow well in the Ethiopian highlands where one of their staple foods, the Ethiopian banana, has been afflicted by
emerging pests,
disease and blasts of intense heat,» Bocinsky
said.
We also observed some similarities between our findings and other
emerging gut microbiota studies in multiple sclerosis; whether these indicate a «gut signature» of multiple sclerosis or of broader autoimmune
disease remains to be determined,»
said Professor Helen Tremlett, lead author of the European Journal of Neurology study.
A poliolike ailment appears to have struck cattle in Kansas in the early 1950s,
says Jack Woodall, an
emerging -
diseases expert at the Federal University of Rio de Janeiro in Brazil.
The best countermeasures to bioterrorism, Franz
says, are the same ones already used to combat infectious
disease: «Supporting the public - health system is crucial because it would be very hard to tell
emerging disease from bioterrorism.»
New patterns of
disease might
emerge (see # 8), he
says, or pollinating insects might become extinct, leading to widespread crop failure.
«Our results indicate that based just on the pattern of virus attachment the H7N9 currently
emerging in China has the potential both to cause severe pulmonary
disease and to be efficiently transmitted among humans,»
says Dr. Kuiken.
The rise of modern, deadly plagues such as AIDS and SARS is particularly devastating because the «golden age of immunization during the last half century gave us a sense of triumphalism about infectious
diseases,»
says Stephen S. Morse, a Columbia University biologist and cofounder of ProMed, a global program for monitoring
emerging infectious
diseases.
«We're not ready for another
emerging infectious
disease that may disproportionately affect pregnant women or their fetuses or babies,» she
says.
«Being able to track the duration of fevers and the return of fevers could help us learn more about an influenza season as it is
emerging and possibly provide information about other infections, including new
emerging infectious
diseases,» Polgreen
says.
Disease wiki The site excels at natural - language processing, says Larry Madoff, founder and editor of the Program for Monitoring Emerging Diseases (ProMED), a global electronic mailing list that receives and summarizes reports on disease outbreaks and that was one of HealthMap's first sources o
Disease wiki The site excels at natural - language processing,
says Larry Madoff, founder and editor of the Program for Monitoring
Emerging Diseases (ProMED), a global electronic mailing list that receives and summarizes reports on
disease outbreaks and that was one of HealthMap's first sources o
disease outbreaks and that was one of HealthMap's first sources of data.
«Many of the
diseases associated with childhood abuse typically
emerge in middle and later stages of adulthood — decades after the abuse actually occurred,»
said Chiang, a postdoctoral fellow with Northwestern's Foundations of Health Research Center and its Institute for Policy Research.
The World Health Organization urges countries to augment their official
disease surveillance efforts — which draw information from networks of doctor's offices, hospitals, and public health laboratories — with what's known as «event - based surveillance,»
said Dr. Larry Madoff, editor of ProMED, the Program for Monitoring
Emerging Diseases.
«These results are highly relevant to clinical inflammatory bowel
diseases because GMSCF - impaired function is now
emerging as one of the best predictors of IBD severity,»
said the study's senior author, Miriam Merad, MD, PhD, Professor in the Department of Oncological Sciences, the Tisch Cancer Institute and the Immunology Institute, at the Icahn School of Medicine at Mount Sinai.
«Bd is the first
emerging disease shown to cause the decline or extinction of scores of populations of amphibians not otherwise threatened around the world,» Goldberg
said.
Following the largest Ebola epidemic in history last year, which claimed the lives of more than 11,000 people in West Africa and ultimately spread to the U.S., public health officials remain concerned about healthcare workers contracting Ebola or other
emerging infectious
diseases such as SARS and pandemic influenza,
says Rachael Jones, UIC associate professor of environmental and occupational and health sciences, one of four co-investigators at UIC.
Neuroscientists believe that consciousness
emerges from the material stuff of the brain primarily because even very small changes to your brain (
say, by drugs or
disease) can powerfully alter your subjective experiences.
«TWEAK and its signaling receptor, Fn14, have
emerged as a fundamental molecular pathway regulating tissue responses after acute tissue injury and in many different contexts of chronic injury and
disease»
said Linda Burkly, Ph.D., Senior Distinguished Investigator, VP, Biogen, Inc., and co-senior author on the current study.
He
said the work may prove to be significant in light of the fact that nearly all
emerging diseases discovered over the past two decades have originated in animals.
The surge in human cases is cause for alarm,
says Guan Yi, an expert in
emerging viral
diseases at the University of Hong Kong in China.
The new predictive features that
emerged may give researchers new clues about the mechanisms of the
disease, he
says.
«There's an
emerging theme in Alzheimer's genetics that the immune system may be strongly involved in the onset of Alzheimer's
disease,»
said co-corresponding author Philip De Jager, MD, PhD, who directs the Program in Translational NeuroPsychiatric Genomics at the Ann Romney Center for Neurologic Diseases at BWH.
Mariette: You raise a fascinating area of what some people have looked at the moral responsibilities that we have as well, especially around
emerging diseases or fast - moving
diseases and the need to understand them scientifically, where we know for a fact, as you've
said, we can mitigate some symptoms, but we're also trying to gather data so that we make sure our therapeutics are very sound.
«Triple - negative breast cancer continues to be a severe health problem, demanding the consideration of
emerging long non-coding RNAs as biomarkers and therapeutic targets in combatting this
disease,»
said Liquing Yang, Ph.D., assistant professor in the Department of Molecular & Cellular Oncology.
Collagen, a structural protein often involved in scarring and wound healing, is
emerging as an important factor in a number of other
diseases, Eliceiri
says.
More broadly, he
said, «These findings are part of an
emerging theme that there is a whole spectrum of
diseases that includes ALS, and some forms of dementia and myopathy, that are caused by disturbance in the behavior of these structures that perturbs cellular organization.»
In fact, Olshansky
says, the threats posed by obesity and
emerging infectious
diseases such as AIDS are largely responsible for his pessimism about 150 - year life spans.
Lead researcher Dr Justin O'Grady, from UEA's Norwich Medical School,
said: «This type of technology will revolutionize the way that we characterize the rapid spread of
emerging antibiotic - resistant infectious
diseases.
Still, «the ban could hamper our ability to learn about the epidemiology of neglected
diseases emerging out of conflict zones»,
says infectious
disease expert Peter Hotez at Baylor College of Medicine in Houston, Texas.
«The only way to prevent
emerging diseases from coming to the US is to stop them in their tracks in the countries where they arise,» he
says.
«The Army was able to move so quickly in developing, manufacturing and testing a Zika vaccine because of its extensive experience with this vaccine platform and long standing investments in the understanding and mitigation of flaviviruses, like yellow fever, dating back to the founding of WRAIR,»
said Dr. Kayvon Modjarrad, Zika program co-lead and associate director for
Emerging Infectious
Disease Threats at WRAIR's MHRP.
«Clarifying how
disease outbreaks subside will help us predict, and respond to, other
emerging pathogens in plants, wildlife — and in humans,» Voyles
said.
Experts
said that
Disease X may
emerge from a variety of sources and may strike anytime.
'' [If] SHERLOCK can be developed to its full potential it could fundamentally change the diagnosis of common and
emerging infectious
diseases,» study co-author Deb Hung
says.
Richard L. Gallo, MD, PhD, professor of medicine and chief of UC San Diego's Division of Dermatology and the Dermatology section of the Veterans Affairs San Diego Healthcare System,
says that several unexpected associations between fluctuations of the body's vitamin D3 and infectious
disease have
emerged in recent investigations.
«This gift that creates the Alpern Fund provides a beacon of hope for millions of individuals who suffer from devastating
diseases that might be eliminated by novel treatments that we believe will
emerge from stem cell research,»
says James Douglas Engel, a professor of Developmental Biology at the UofM Medical School and chair of the Department of Cell and Developmental Biology.
«Pet obesity continues to
emerge as a leading cause of preventable
disease and death in dogs and cats,»
said Veterinarian Ernie Ward, lead researcher and founder of the association.
Given the urgency associated with
emerging infectious
disease, it is always our goal to respond as quickly as possible with effective solutions,»
said Shelley Stanford, DVM, Group Director, Companion Animal Division Veterinary Professional Services, Zoetis.