Sentences with phrase «said obesity drugs»

Novo said obesity drugs will account for more than one third of its overall research and development spend this year, up from around 10 percent five years ago.

Not exact matches

The world's largest maker of diabetes drugs said on Tuesday it would aim to develop medicines that treat obesity - a major cause of diabetes - at least as effectively as surgery.

Some say certain Alzheimer's and obesity drugs currently in trials could be as big as Lipitor.

People with morbid obesity (defined as a body mass index above 40) have a metabolic disease too complicated to treat with just drugs, diet or exercise; and most will regain weight lost through those methods, he says.

The findings could offer scientists a new target for developing drugs against obesity and other appetite - related disorders, the researchers say.

If the hormone suppresses appetite in people, it could be a great obesity drug, Rosen says.

This knowledge potentially means, that in the future we can target drugs to activate the genomic regions and browning factors like KLF11 in the treatment of obesity,» says Anne Loft.

«While it is known that these drugs can increase the risk of obesity in adults, it is unknown whether a woman's antidepressant use during pregnancy increases the risk of metabolic disturbances in her children,» Holloway says, adding the goal of their project was to determine whether maternal exposure to a commonly used antidepressant is related to the development of fatty liver, an outcome commonly seen with obesity, in the offspring.

Nick Finer, a specialist in obesity at the Luton and Dunstable Hospital, says: «There's a great attraction in drugs that could work within the gut and strengthen satiety signals from there.

«Our results provide a large body of evidence demonstrating that the harmine drug class can make human beta cells proliferate at levels that may be relevant for diabetes treatment,» said senior study author Andrew Stewart, MD, Director of the Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine.

«We know that amlexanox works to reverse obesity and insulin resistance in part by resolving chronic inflammation and increasing energy expenditure, but that's not the whole story of the drug's effects,» said Shannon Reilly, first author of the study.

Recently the drug industry, desperate to uncover a solution to obesity, say they found a type of this hormone called CRF2 that cuts hunger without added stress.

Drugs that target this protein may one day help fight obesity, says lead researcher Jeffrey Gordon, a molecular biologist at Washington University in St. Louis, Missouri.

«Together, our findings indicate that these molecular regulators, TRIP - Br2 and GATA3, could be viable targets for small drug molecules that could serve as potential therapeutic agents against obesity,» Liew said.

Matthias Tschöp, an obesity researcher at the University of Cincinnati, says understanding how NAPE affects our appetite for fat would hopefully lead to new drugs that muzzle hunger, without eliminating it.

Students more likely to participate in free - and reduced - price lunch programs are among the same populations most likely to suffer from obesity and related health risks, said Janet Peckham, an economist in the Office of the Commissioner at the U.S. Food and Drug Administration and lead author of the study.

The researchers say the next step is to develop small molecules or drugs that regulate p75 NTR to reproduce this effect and potentially serve as a therapeutic intervention for obesity and metabolic syndrome.

«The obesity drug blocked the lipogenesis fantastically and the tumors regressed and didn't metastasize,» Pandolfi says.

«We hope that finding a drug that blocks FATP4 activity may provide a better, or at least an alternative, treatment strategy for obesity,» says Dr. Lodish.

The study should not be interpreted to mean that the drug shouldn't be used at all, says Dr. Ryan, who prior to 2008 served as a consultant for Abbott and other manufacturers of obesity drugs.

«Unfortunately, this drug is all too easy to get,» says Scott Isaacs, MD, an endocrinologist and obesity specialist at Emory University School of Medicine in Atlanta.

This is obviously an oversimplification, Dr. Celi says, but the demonstration that adults have brown fat that can be activated is, nevertheless, «powerful proof of concept» that the tissue could be a target for obesity - fighting drugs or even environmental fat - fighting strategies.

I'm going to give it a try,» or they can say, «Well, I think I'm going to wait for a few more trials, FDA approval,» and they can sit back, but more and more, the public are ready to evaluate science simultaneously and take these very common sense, very easy... Well, behavior is not an easy thing to change, but far easier than taking chemotherapy or disease modifying drugs that are going to shut down your immune system and give you life - threatening side effects, that could let you get your life back from an autoimmune condition, or a serious psychiatric problem, or a severe diabetes, obesity, and heart disease, things that are completely under their control.

Drugs can alleviate symptoms but they can't change the «pathophysiology,» he says, and concludes: «It is time to bust the myth of the role of saturated fat in heart disease and wind back the harms of dietary advice that has contributed to obesity.»»