«Our study identified miR - 182 as a glioblastoma tumor suppressor that reduces the expression of several oncogenes that promote cancer development,»
said senior author of the study Alexander Stegh, an assistant professor in the Ken and Ruth Davee department of neurology and of medicine at Northwestern University Feinberg School of Medicine.
«We now know that the megacheirans had central nervous systems very similar to today's horseshoe crabs and scorpions,»
said the senior author of the study, Nicholas Strausfeld, a Regents» Professor in the University of Arizona's department of neuroscience.
The findings could allow clinicians to prioritize the scarce treatment resources available and provide them to the sickest patients,
said the senior author of the study, Yoshihiro Kawaoka, a virology professor at the UW - Madison School of Veterinary Medicine.
«We've never had a drug that inhibits the release of glutamate, but we presume it would have dramatic effects,»
says the senior author of the study, Robert H. Edwards, MD, UCSF professor of neurology and physiology.
The finding also suggests the possibility of new applications for Onyx - 015,
says the senior author of the study, Michael Korn, MD, UCSF assistant adjunct professor of medicine.
Chloroquine has become ineffective against malaria, and resistance to the other frontline drugs is emerging,»
says senior author of the study Professor Dominic Kwiatkowski, of the Wellcome Trust Sanger Institute and Oxford University.
«Our previous findings showed that people who ate this ingredient gained less weight — but we did not know why,»
says the senior author of the study from Imperial, Professor Gary Frost.
Not exact matches
«We were surprised by the large number
of concerns mothers had, and we were very concerned by how particular concerns were strongly related to giving up with breastfeeding» - such as worries about babies not getting enough nutrition,
said Laurie A. Nommsen - Rivers, the
study's
senior author, from Cincinnati Children's Hospital Medical Center.
«About 50 percent
of the brain's pathways are tied in some to way to vision and visual processing,»
said Dr. Steven Galetta, chairman
of neurology at N.Y.U. Langone Medical Center and
senior author of the
study, which was published in The Journal
of Neuro - Ophthalmology.
«It will be important to see whether these results can be confirmed in future, larger
studies and in other populations,»
said senior author Thomas Newman, MD, MPH, a professor
of pediatrics and epidemiology and biostatistics at UCSF and a pediatrician at UCSF Benioff Children's Hospital.
The
study's
senior author, Associate Professor Natasha Nassar from the University
of Sydney Menzies Centre for Health Policy
said: «While the association between being born earlier — lower gestational age — and poorer developmental outcomes is well established, our results revealed that poor development is further exacerbated in the case
of planned birth, where a considered decision made to deliver an infant determines gestational age.
«For parents whose major concern about Ritalin and Adderall is about the future risk for substance abuse, this
study may be helpful to them,»
says Steve S. Lee,
senior author of the
study, a psychology professor at UCLA.
«Maybe the baby cries less if the mom and dad are happier,»
said Kristen Kjerulff, professor
of public health sciences and
senior study author.
«We do have a real problem with way too many multiple births in the United States with consequences to both mothers and babies,»
said Adashi, the
study's
senior author and former dean
of the Warren Alpert Medical School
of Brown University.
«The most serious risk for very young children is choking on small toys or small parts
of toys,»
said Dr. Gary Smith,
senior author study and director
of the Center for Injury Research and Policy at Nationwide Children's Hospital in Columbus, Ohio.
When Time magazine
senior editor Jeffrey Kluger contacted the
authors of some
of the
studies cited by William Sears for an article he wrote in May 2012, the scientists
said it was unfair that Sears had used their work as evidence against sleep training.
«Turkey in many ways is a wild card in this coalition equation,»
said Juan Zarate, a
senior adviser at the Center for Strategic and International
Studies and
author of «Treasury's War, the Unleashing
of a New Era
of Financial Warfare.»
«Evolution is one
of the key concepts in understanding biology,»
said Sara Brownell,
senior author of the
study and assistant professor with the school.
There was an ancient paradigm about the «fitness cost
of antibiotic resistance,» but the emergence
of the new technologies
of high - throughput sequencing has changed the field, allowing researchers to
study bacterial pathogenesis at the genome scale,»
said Dr. David Skurnik,
senior author of a new Bioessays article.
«The newborn mice inherited a very altered, skewed population
of microbes,»
said Eugene B. Chang, MD, Martin Boyer Professor
of Medicine at the University
of Chicago, Director
of the Microbiome Medicine Program
of the Microbiome Center, and
senior author of the
study, published this week in the journal Cell Reports.
«Many
of the key players orchestrating DNA methylation had previously been characterized, but what we didn't fully realize before this
study is that they all work together in an elegant way,»
said Scott Rothbart, Ph.D., assistant professor at Van Andel Research Institute (VARI) and the
study's
senior author.
It turns out that taste buds are doing more than we think,»
says senior author of the University
of Michigan - led
study Scott Pletcher, Ph.D., associate professor in the Department
of Molecular and Integrative Physiology and research associate professor at the Institute
of Gerontology.
«From purely looking at the DNA sequences we can conclude that snakes retain many enhancers that, based on mammalian
studies, we thought were limb enhancers,»
says senior study author Douglas Menke, a geneticist at the University
of Georgia.
«Previous
studies have linked intake
of high fructose corn syrup sweetened beverages with asthma in school children, but there is little information about when during early development exposure to fructose might influence later health,»
said Sheryl L. Rifas - Shiman, MPH, a
study lead
author and
senior research associate at Harvard Medical School and Harvard Pilgrim Health Care Institute.
«These bacteria are part
of an orchestrated series
of events that make lipid absorption more efficient,»
said the
study's
senior author, Eugene B. Chang, MD, the Martin Boyer Professor
of Medicine and director
of the NIH Digestive Diseases Research Core Center at the University
of Chicago Medicine.
«This is like designing a scalpel to precisely seek out and destroy a cancer — but with a pill and without surgery,»
said TSRI Professor Matthew Disney,
senior author of both
studies.
«This model could have far - reaching implications to advance the understanding and treatment
of neurological disorders,»
said Svendsen,
senior author of the Cell Stem Cell
study.
«Since the loop has been found to be a key segment in prion protein aggregation, this site could be targeted for the development
of new therapeutics designed to block prion conversion,»
said Christina Sigurdson, DVM, PhD, associate professor at UC San Diego and UC Davis and
senior author of the
study.
«We present an interdisciplinary approach to
studying immunotherapy and immune surveillance
of tumors,»
said Benjamin Greenbaum, PhD, the
senior author, who is affiliated with the departments
of Medicine, Hematology and Medical Oncology, Pathology, and Oncological Sciences at The Tisch Cancer Institute at the Icahn School
of Medicine at Mount Sinai.
«The women who had a diagnosis
of a sleep disorder recorded in their medical record most likely had more severe presentations,»
said Aric Prather, PhD, assistant professor
of psychiatry at UCSF and
senior author of the
study.
«That's astonishing,»
says geneticist Sekar Kathiresan, director
of preventive cardiology at Massachusetts General Hospital and
senior author of The Lancet
study.
As they
studied brain activity in the knockout mice, the researchers also found prominent changes in a receptor in the brain known as mGluR5 and other proteins that support the function
of neurons and synapses,
said co-lead
author Xiaoming Wang, M.D., Ph.D.,
senior research associate in Duke's department
of pediatrics.
«It's already clear that this method opens the door to creating new types
of compounds and new types
of bonds,»
says Phil S. Baran, PhD,
senior author of the
study and Darlene Shiley Professor
of Chemistry at TSRI.
«Identifying which
of these candidate genes actually causes variation in responses to cold snaps will give us the potential to understand whether evolution to climate change can occur in both wild and domesticated animals, allowing us to better predict which species or breeds will be «winners» and «losers» and to better mitigate the effects
of anthropogenic climate change on a wide range
of organisms from beneficial pollinators to invasive pests,»
said Theodore Morgan an associate professor
of evolutionary genetics in the Division
of Biology at Kansas State University and
senior author of the
study.
said Clifton Ragsdale, PhD, professor
of neurobiology at UChicago and
senior author of the
study.
The total «knockout»
of the gene makes the model more effective for
studying SHANK3 - related autism and Phelan - McDermid syndrome in humans, many
of whom are missing the gene completely,
said senior author Yong - hui Jiang, M.D., Ph.D., an associate professor
of pediatrics and neurobiology
«This was the first
study to detect the recent TB outbreak in Zimbabwe, and the first anywhere to suggest an association between rising TB incidence and national economic decline in the absence
of armed conflict,»
said Michael Silverman, assistant professor at the Dalla Lana School
of Public Health and
senior author of the
study.
«The median percentage reduction in seizure frequency was more than 29 percent for patients on a low - dose regimen
of everolimus and nearly 40 percent for patients with high - dose regimen to the drug,»
says David Franz, MD, founding director
of the TSC Clinic at Cincinnati Children's Hospital Medical Center and the
study's
senior author.
said Megan Donahue, associate researcher at the Hawai'i Institute
of Marine Biology (HIMB) in SOEST and
senior author of the
study.
«We are making progress,»
said Anne Hart, professor
of neuroscience at Brown and
senior author of the new
study in the journal eLife.
Professor Janet Treasure from King's College London's Institute
of Psychiatry and
senior author on both
studies says: «Patients with anorexia have a range
of social difficulties which often start in their early teenage years, before the onset
of the illness.
We wanted to find a way to assess brain damage that could predict the development
of dementia associated with vascular diseases,»
said Daniela Carnevale, Ph.D., the
study's
senior author and assistant professor at Sapienza University
of Rome, based in Neuromed Institute.
«Much like the spread
of human disease in populated areas, urban centers can foster increases in multiple disease types in wild animals,»
said McGraw,
senior author of the
study.
«People had trouble picking out the correct logo even when it was right in front
of them,»
said Alan Castel, an associate professor
of psychology at UCLA and
senior author of the
study, who showed in 2012 that most people did not know the location
of a bright red fire extinguisher near their office, even though they had walked by it hundreds or thousands
of times.
said Richard Zigmond, PhD,
senior author on the
study and professor
of neurosciences, neurosurgery, and pathology at Case Western Reserve University School
of Medicine.
Senior author, Professor Anjali Goswami (UCL Genetics, Evolution & Environment and UCL Earth Sciences),
said: «Our findings refute those
of other
studies which overlooked the fossils
of placental mammals present around the last mass extinction.
«Our work demonstrates that the generation
of genome sequences from a large number
of archaic human individuals is now technically feasible, and opens the possibility to
study Neandertal populations across their temporal and geographical range,»
says Janet Kelso, the
senior author of the new
study.
«In addition to INSIGHTS» focus on individual children's strengths and needs, our
study illustrates the importance
of understanding and supporting classrooms as a whole at the transition to formal schools,»
said McClowry, professor
of applied psychology at NYU Steinhardt and the
study's
senior author.
«Neither HPV vaccination nor program eligibility increased the risk
of pregnancy nor non-HPV-related STIs among females aged 14 - 17 years,»
says Dr. Lévesque, the
senior author of the
study.
«For a long time, we've thought
of brain imaging
studies as mainly a way to corroborate or confirm aspects
of brain function and pathology that we had already identified from
studying a patient's behavior,»
said Aysenil Belger, PhD, professor
of psychiatry and psychology at UNC and the
study's
senior author.