It turns out the response to the vaccine has been variable between different Clades and there is a great deal (up to 15 %) of genetic variability even within
the same Clade.
Results: Phylogenetic analysis of 77 K. pneumoniae (48 clinical and 29 non-clinical isolates) demonstrated that the two groups were intermixed throughout the tree and in some cases resided in
the same clade, suggesting recent divergence from a common ancestor.
Deep sequencing of isolates taken from a single patient carrying MRSA for the longest period revealed that although all isolates were of
the same clade, there were small genetic differences between them, suggesting bacterial diversity within a single carrier.
Thus, the morphological similarities that led to their classification into
the same clade are not the result of descending from a common ancestor, but reflect adaptations to related environments (convergent evolution).
Not exact matches
«This suggested that multiple
clades of the
same lineage were circulating in the hospital at the
same time.»
The Bioko viruses cover the whole range of SIV genetic diversity, and each Bioko SIV
clade is most closely related to viruses circulating in hosts of the
same genus on the African mainland rather than to SIVs of other Bioko species.
HPAI A (H5N8) viruses cluster in the
same haemagglutinin (HA)
clade as A (H5N1) viruses from Asia and A (H5N6)-- which has caused severe disease in humans in China — so the possibility of transmission from birds to humans can not be completely ruled out.
The env gene (complete gp160) of 10 viruses representative of the five primary
clades A to E1 was amplified by PCR from viral RNA using specific primers, digested with XbaI and NotI and inserted in the
same sites in the pNL - lacZ / env - Ren 2 with the resultin
bilaterians: A
clade of animals whode members share: bilateral symmetry, are triploblastic (three tissue layers: ectoderm, mesoderm, endoderm), and with HOX genes in one or more clusters with the genes within a cluster arranged in the
same order as the body parts they affect.