Rather,
the same early risk factors have been found to be associated with childhood - onset CP in both genders (Barker and Maughan 2009; Côté et al. 2006; Lahey et al. 2006).
Not exact matches
The most recent study report described in these
same regions decreased tissue levels of 5 - HT and tryptophan hydroxylase, the synthesizing enzyme for serotonin, and no evidence of excessive serotonin degradation as assessed by levels of 5 - hydroxyindoleacetic acid (the main metabolite of serotonin) or ratios of 5 - hydroxyindoleacetic acid to serotonin.30 A recent article described a significant association between a decrease in medullary 5 - HT1A receptor immunoreactivity and specific SIDS
risk factors, including tobacco smoking.40 These data confirm results from
earlier studies in humans39, 41 and are also consistent with studies in piglets that revealed that postnatal exposure to nicotine decreases medullary 5 - HT1A receptor immunoreactivity.42 Animal studies have revealed that serotonergic neurons located in the medullary raphe and adjacent paragigantocellularis lateralis play important roles in many autonomic functions including the control of respiration, blood pressure, heart rate, thermoregulation, sleep and arousal, and upper airway patency.
«Even within individuals exposed to the
same risk factor, different strategies may be appropriate to treat the symptoms of autism in
early development versus maturity,» said Page.
The reasoning behind this proposition is that: A) EBHV programs are designed to serve women categorized as «at -
risk» due to a variety of demographic
factors, including single - parent household status, age at time of first pregnancy, being categorically undereducated, under or unemployed, and meeting federal standards of living at or below the poverty line; B) these programs serve women during pregnancy and / or shortly after the birth of their children, offering an excellent chance for the
early prevention of trauma exposure; and C) intervention services are provided at the
same times that attachment (whether secure or insecure) is being developed between mothers and children, providing the opportunity that generational
risk may be mitigated.
A question for future research is whether
risk factors exert their effects for only a limited period (suggesting that the
same risk factors we measured in
early childhood, such as losing a parent, would predict adult - onset MDD if they occurred in late adolescence) or whether
risk factors are developmentally sensitive, and those that predict juvenile - onset MDD are qualitatively different from those that predict adult - onset MDD.