«After testing the drug in mice, we wanted to check whether JQ1 would have
the same effect in humans,» explained co-first author Sarah McMahon, a UCSF graduate student in Haldar's lab.
Now researchers in the U.S. and Canada want to hold the first anti-aging clinical trial to see if they can replicate
the same effect in humans using a diabetes drug called metformin.
It is, however, too early to say whether corticosteroids have
the same effect in humans.
Neonicotinoids gained popularity as pesticides in the 1990s in part because they target the central nervous system of crop - destroying insects, but don't have
the same effects in humans.
Not exact matches
Of course, it remains to be seen if the
effects are the
same in humans (and, as such, there's no word on appropriate dosage).
But the
effect upon
human community is much the
same in either case, Myths, Models and Paradigms (New York: Harper & Row, 1974).
Towards the fulfillment of His purposes He has brought man into being and He offers to His
human children the privilege of co-operating with Him so that they may have a share
in the
effecting of these ends and, at the
same time, find a supreme joy for themselves as they are related to Him and participate
in His communication of life.
Why not assume instead that, if it is by reason of the cosmic structure, and not by chance, that man has become «legion», by the
same token it is not through chance, but through the prolonged
effect of «cosmic coiling», that the
human layer is weaving and folding -
in upon itself
in the way we see it to be doing?
People are not the
same there are many Ranks, Degrees, Levels of
Human Waves from down scratch status to highest above the sky financial status and surely that has direct
effect on mentality and humor among each level... beside that there are the peasants and tribals
in remote areas and cities out skirts who work
in the cities but there are people of the cities which are highly educated and good status.
The amount of conceptual novelty it can introduce is tiny indeed, and the «cleverest» DNA - molecular - occasion
in the world is oblivious of the fact that its aims may have an
effect on the welfare of the
human «living person» who happens to inhabit the
same organism!
In 2007, researchers published the first randomized, controlled study of the effect of being raised in an orphanage; that study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional developmen
In 2007, researchers published the first randomized, controlled study of the
effect of being raised
in an orphanage; that study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional developmen
in an orphanage; that study, and subsequent research on the
same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with
human attachment and differences
in functioning in brain areas related to emotional developmen
in functioning
in brain areas related to emotional developmen
in brain areas related to emotional development.
It's the
same for
human infants: stationary maternal holding or being rocked
in a bassinet (or mechanical swing) will not produce the
same effect on the infant as being carried during a walk.
«It's always a concern to make a direct extrapolation to
humans, but they provide a small amount of evidence that the
same effect happens
in humans, and then put the results back into animals — that was clever.»
«We have now found a potential mechanism, and at this point
in our research, we need to test
human participants
in a blinded, placebo controlled clinical study — the
same technique we used to study the behavioral
effects of acupuncture
in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.
He thinks the hormone might also boost fertility
in men, as many hormones have been found to have the
same effects in mice and
humans.
First, however, the researchers will have to demonstrate whether the
same principals hold true
in humans, without side
effects.
A chemical produced
in the pancreas that prevented and even reversed Type 1 diabetes
in mice had the
same effect on
human beta cells transplanted into mice, new research has found.
Another study by a different group
in the
same journal
in October 2009 looked at ART
effects on epigenetics (non-DNA changes
in genes)
in humans.
If acetate does the
same in humans, dietary fibre may hold the key to curbing appetites and perhaps help battle obesity — although boosting our intake might not be the best way to see an
effect.
In an accompanying paper, MacKinnon's team notes that scorpion toxin — a potent potassium channel inhibitor — has the same effect on pores in S. lividans and those of the fruit fly Drosophila, whose nuclei are organized similar to those of human cell
In an accompanying paper, MacKinnon's team notes that scorpion toxin — a potent potassium channel inhibitor — has the
same effect on pores
in S. lividans and those of the fruit fly Drosophila, whose nuclei are organized similar to those of human cell
in S. lividans and those of the fruit fly Drosophila, whose nuclei are organized similar to those of
human cells.
In lab experiments, the researchers isolated exosomes from specialized
human cardiac stem cells and found that exosomes alone had the
same beneficial
effects as stem cells.
If the
same result holds true
in humans, it could provide an explanation for why drugs that target NMDA receptors have failed to capture ketamine's full
effects.
Nobody knows if adding the interleukin - 4 gene would have the
same effect in a different pathogen, but «the question instantly became what would happen if somebody tried this with smallpox or other
human viruses,» says Seamark.
Digging deeper, the researchers discovered that this pregnancy - like state was being caused by the
human growth hormone, explains Professor Schuit: «
In mice, the human growth hormone has the same effect as hormones that are produced by the placenta in pregnant mic
In mice, the
human growth hormone has the
same effect as hormones that are produced by the placenta
in pregnant mic
in pregnant mice.
For Longo, it all added up: The
same growth genes that regulate aging and protect against age - related diseases
in yeast, mice, and roundworms might have an identical
effect in humans.
Whether the
same effect could be attained
in the much more complex nervous systems of adult
humans is unknown, says José Fernando Maya Vetencourt, the lead author of the study and a researcher
in neurobiology at the Scuola Normale Superiore
in Pisa, Italy.
Preliminary evidence suggests that arsenic may have the
same effect on telomerase
in other cancers;
human trials are ongoing.
If the
same thing happens
in humans, the full
effects of accidents like Chernobyl, above - ground atomic tests, and the bombings of Hiroshima and Nagasaki won't be known for generations.
Especially since this approach does not take into account the
effects that can occur
in humans when the chemicals are present at the
same time
in a cocktail.
«If scientists want to test drugs for dementia, Alzheimer's or autism, ideal models would react similarly to
humans in regards to the reduction of symptoms, outbreak of side
effects, such as enduring the
same lesions as
humans do, or exhibiting similar behavioral characteristics,» said Latham, who's with the College of Agriculture and Natural Resources and an MSU AgBioResearch scientist.
Humans and adult chimps seem more likely to catch a yawn when the original yawner is someone they know, but experiments
in puppies have not found the
same familiarity
effect, and the researchers didn't see this
in budgies either.
Drugs that reduce this protein
in humans may have the
same protective
effect.
But he adds that the
effect in humans matches the
same biological pattern found
in other animals, such as rats.
The
same effect was seen
in a mouse model of
human brain cancer containing this gene fusion.
However, the
effects of introducing these particles are not expected to be the
same across the globe, and the offsetting of
human - induced changes
in other quantities such as rainfall and weather patterns may not work as well as for temperature.
In particular, they will test if social threats and biological threats are processed in the same way, and whether membership in a social group has an effect on how humans respond to threat
In particular, they will test if social threats and biological threats are processed
in the same way, and whether membership in a social group has an effect on how humans respond to threat
in the
same way, and whether membership
in a social group has an effect on how humans respond to threat
in a social group has an
effect on how
humans respond to threats.
We show that subpopulations of
human astrocytes, generated by activation of different signaling pathways
in the
same population of
human glial precursor cells, have markedly different
effects when transplanted into the injured spinal cord.
Tests on
human beta cells
in the lab showed that the hormone had the
same effect as
in isolated rat beta cells.
The combination of fatty acids used by the python to accomplish its own, healthy enlargement seems to have the
same effect in lab mice, and now researchers hope to apply the
same principle to the treatment of
human heart problems.
Whole - body Induced Cell Turnover (WICT) consists of the qualitative and quantitative coordination of targeted cell ablation with exogenous cell administration so as to
effect the replacement of a patient's entire set of endogenous cells with exogenous cells (of the
same quantity and cell type as the ablated endogenous cells they are replacing) derived from
human pluripotent stem cells and directionally differentiated
in vitro prior to their administration.
Individual CLA isomers appear to be protective or beneficial
in isolated studies... but when you actually feed an animal or
human a CLA supplement with the
same isomer ratios (not found
in nature), the benefits either disappear or get counterbalanced by a negative
effect.
There was previous evidence
in studies of rodents and younger
humans that exercise boosted tryptophan availability, but it wasn't clear whether the
same effect would occur
in older adults.
Probiotics mean specific strains which have been characterized to show specific
human health
effects, while other strains of the
same species may not have them and
in fact probably don't.
More research is needed to determine if the
same effects are present
in humans, but lemongrass could offer relief to people
in remote parts of the world who are unable to receive modern medical treatment for malaria.
Whey is composed of the
same basic proteins that are found
in human breast milk and has the
same side
effects profile as
human breast milk.
While the exact mechanism of the
effect on the ubiquitin pathway is not currently known, studies
in both animal models and
humans have shown the
same effect, reduced protein breakdown, which helps maintain more muscle mass.
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«
In the spring the qualities of heavy, dense, damp and cool are in the environment, and because of seasonal effects, we as humans start to accumulate some of those same qualities in our bodies, especially after the wintertime when we've been eating warm, heavier foods that mitigate the cold and dry qualities of winter,» explains Erin Casperson, an Ayurveda Health Counselor and Yoga Journal LIV
In the spring the qualities of heavy, dense, damp and cool are
in the environment, and because of seasonal effects, we as humans start to accumulate some of those same qualities in our bodies, especially after the wintertime when we've been eating warm, heavier foods that mitigate the cold and dry qualities of winter,» explains Erin Casperson, an Ayurveda Health Counselor and Yoga Journal LIV
in the environment, and because of seasonal
effects, we as
humans start to accumulate some of those
same qualities
in our bodies, especially after the wintertime when we've been eating warm, heavier foods that mitigate the cold and dry qualities of winter,» explains Erin Casperson, an Ayurveda Health Counselor and Yoga Journal LIV
in our bodies, especially after the wintertime when we've been eating warm, heavier foods that mitigate the cold and dry qualities of winter,» explains Erin Casperson, an Ayurveda Health Counselor and Yoga Journal LIVE!
As noted
in this article, polyphenols may have important
effects on
human health because they are metabolized by the
same pathways as xenobiotics and endogenous hormones.
Though it's premature to generalize based on animal results that the
same phenomena would hold true
in people, Swithers says, she notes that other
human studies have already shown a similar
effect.