Sentences with phrase «same gene pathway»

Furthermore, eliminating a number of the genes known to work in the same gene pathway as Notch created similar chaotic patterns in the embryos, they report in the 18 June issue of Nature.

Though the research is currently limited to animals only, scientists have been able to significantly increase muscle building when muscles have been placed under loaded stretches - presumably by creating additional muscle damage and by stimulating the same gene pathways switched on by the tension of muscle contraction.

Not exact matches

«We are not fixing the gene; the mutation is still there,» says Belmonte, «Instead, we are working on the epigenome and the mice recover the expression of other genes in the same pathway.

Different genes could affect the same pathway, meaning that the different genetic anomalies found in people with ASD could potentially all be affecting similar pathways.

The researchers also examined gene expression in pre-existing skin biopsies from the same twins to identify possible gene pathways linked to acne.

Their results turned up an unexpected commonality: Early on in each of the diseases, genes involved in the same specific pathway of cell death appeared to be activated.

It is based on the growing realization that many cancers share the same gene mutations or pathways to grow.

For example, it is not yet clear whether these genes are regulated by the same conserved signaling pathways present in Dipterans, or whether novel immune signaling pathways may also exist in Hymenoptera.

While the promoter mutations were not near known pancreatic cancer genes, the team discovered that they affected some of the same biological pathways inside cells.

«It may have just a subtle influence,» suggests Dr. Cook, «but if we find two more autism - associated genes with the same prevalence — possibly additional hits along the same pathway — 16 percent cubed comes to four in a thousand, close to the frequency of autism.

Basic mammalian biology At the same time, Sumner was conducting a companion study to measure gene activity in the adipose «lipolysis pathway» — which follows the breakdown and mobilization of fat tissue — a major contributor to milk production.

The group then was able to identify the seven genes that functions in the same pathway related to calcium to control the length of sleep.

By assessing the incidence of a particular mutation or the frequency at which certain genes / pathways are altered across multiple patients (of the same tumor type), it should be possible to identify key mutations.

Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.

Gene deletion mutants of the same pathway or with similar fitness alterations in steady conditions can largely differ in their response to dynamic conditions.

The same set of RNAi pathway genes is required for Drosophila defense against FHV and CrPV and both viruses encode a potent VSR.