This abnormality can then be propagated from cell to cell because, when the misfolded version touches the normal one, it can trigger
the same misfolding, thus causing the newly insoluble prions to clump.
Not exact matches
Scientists now know that scrapie is caused by
misfolding proteins in the brain called prions, the
same mechanism that causes Creutzfeldt - Jakob disease in humans.
In its «prion state» the protein can entice healthy proteins of the
same kind to adopt the misfolded prion form — a kind of protein
misfolding chain reaction.