Those molecules are the exact
same molecules as here on Earth, but we now want to see them under very different conditions, very high temperatures and pressures.
If there existed only more or less random occasions, we could not speak of a molecule at all, but, in fact, we are able to identify a single molecule through a long period of time as
the same molecule.
If we make antibiotics in a pharmaceutical vat, do they somehow lose their value compared to the kind made «naturally» by fungus, even if we're getting
the same molecule in the end?
«It can be that a molecule of one handedness has fantastic physiological properties, but
the same molecule with the opposite handedness could have very detrimental properties.»
«It upholds our hypothesis that coalescence is so similar that there's got to be
the same molecules and mechanisms that do it, and we may be able to find a drug that shuts tumor formation down without being toxic to healthy cells in the body,» says Soll, the paper's corresponding author.
And the key to getting it out is
the same molecule that lets all those trees grow: carbon dioxide.
You can see
the same molecule from all sides.»
Surprisingly, the study showed that
the same molecule that assembles and releases new viruses also rearranges itself into different shapes, with each shape controlling a different step of the virus's life cycle.
The structure of Col - P is exciting, says structural biologist Jürgen Engel from the University of Basel in Switzerland, because it's the first example of collagen being combined with more flexible elastinlike structures in
the same molecule.
In our solar system, comets seem to have many of
the same molecules, even amino acids.
Many chemical compounds display a feature called chirality, where two versions — known as enantiomers — exist for
the same molecule.
These same molecules give trees their beautiful fall colors in Michigan.
Many of
the same molecules have been implicated in both declarative and nondeclarative memory and in species as varied as sea slugs, fruit flies, and rodents, suggesting that the molecular machinery for memory has been widely conserved.
The physician - scientist may study the same properties of
the same molecule but for a different reason: because he or she believes that those studies will provide information on the fundamental pathology of a disease or insight into human biology that will provide a better understanding of healthy versus diseased states.
The reason is that, often, drugs do not only bind a single site on a specific molecule, but can also bind and affect other, unrelated sites — either on
the same molecule or on a different one.
«You can get to the point where you've produced in the lab
the same molecule that's occurring in space, but you don't necessarily know what the molecule is,» says Michael McCarthy, a physicist at the Harvard — Smithsonian Center for Astrophysics.
It was chance that he and Brenner were working on
the same molecule at the same time and came to know of each other's work.
Somewhat analogous to a hydrogen bond, the halogen bond (2) arises from an emergent electrophilic region on a molecule's constituent halogen atom, allowing it to attract a net negatively charged species on
the same molecule or on a neighboring molecule (3).
Professor Duncan Wass, whose team led the research, said: «The alcohol in alcoholic drinks is actually ethanol — exactly
the same molecule that we want to convert into butanol as a petrol replacement.
«We found another pathway that is dysregulated, that involves
the same molecule implicated before — mGluR5 — but in an entirely different way,» said Vitaly Klyachko, PhD, an associate professor of cell biology and physiology and the study's senior author.
Ocean acidification in particular, caused as the ocean absorbs carbon dioxide from the atmosphere, is a grave concern for stony corals, because it makes it harder for the animals to passively precipitate skeletons made of calcium carbonate,
the same molecule found in antacids for heartburn and indigestion.
But when a pathogen is present,
this same molecule blocks the plant's innate defense response.»
Now they believe
these same molecules, when the system fails, might be involved in conditions as diverse as Alzheimer's, glaucoma, schizophrenia and autism.
Furthermore, using the specific molecules on the surface of the cancer blood vessels to target therapeutic agents raises the possibility of using
the same molecules to target agents to the cancer cells as well.
Roberts says the group of fungi pigmented with melanin (which includes E. rostratum)--
the same molecule that darkens and protects human skin — seem to be generating more human infections for reasons he does not understand.
Change the orientation of
the same molecule, and it could prove fatal.
Unlike PKA, PKG has the R and C domains on
the same molecule, which prevents them from diffusing away from each other, as in the case of PKA.
Creating molecules in the lab does not prove that
the same molecules exist on dust grains in distant nebulas, but so far Allamandola's technique has an impressive track record.
«It's
the same molecule as the neurotransmitter in the brain, but the molecule in the platelets is produced by cells in the intestine.
Researchers at Kyushu University's Center for Organic Photonics and Electronics Research (OPERA) instead focused on a different type of exciton called an exciplex, which is formed by a hole and electron located on two different molecules instead of
the same molecule.
But
the same molecule is a pollutant closer to the ground.
This is particularly necessary in the cases of carbon monoxide and methane, because their fingerprints in comets tend to overlap with
the same molecules in Earth's atmosphere.
These are
the same molecules that allow nasal cells to respond to odours.
«This study in combination with prior work shows that
the same molecule, p11, mediates the actions of two distinct classes of antidepressants in two totally different types of cells within the brain,» says co-corresponding author Yong Kim, a research assistant professor in the lab.
But in 2008, researchers overcame this problem by packaging Wnt proteins in water - friendly liposomes, which are tiny bubbles that are made of
the same molecules as cell membranes.
This reminds us that
the same molecule can function very differently in different subtypes of cancers, a phenomenon which has often been seen before.»
In the latter case, this means that at any given time, you could have one of two different «versions» of
the same molecule.
For example, triazoles could potentially be used to protect azides from harsh environments required to build another part of
the same molecule.
Also, there's no description of read de-duplication, which is alarming because it suggests that duplicate reads from
the same molecule weren't removed prior to analysis.
We could also attach a CRISPR payload to
those same molecules to trigger self - destruction, or knock out or potentially add a new function to the organism.
«It is worth considering that a peroxide compound in essence contains both the fuel and the oxidizer in
the same molecule and is therefore only one small step away from ignition.
This likely reflects the presence of Aβ and APP / CTFs within the same intracellular location but does not necessarily imply that the antibodies are identifying
the same molecules.
But in polluted air,
this same molecule could travel only half as far.
After the workout, the researchers tested the volunteers» blood again at regular intervals to assess
the same molecules.
In 1993, while at the Sloan - Kettering Cancer Center in New York, Rothman performed the key experiment that has forever linked his work to that of Thomas Südhof and Richard Scheller, by demonstrating that
the same molecules that control this process in the nervous system, in the release of signaling molecules called neurotransmitters, are important to vesicle transport and fusion in all cell types.
For the first time, they've prevented UTIs in mice by vaccinating them with
the same molecules that the bacteria usually use to grab iron and fuel their growth.
Rothman came from a different background in cell biology to discover first serendipitously, and then with extensive follow - up work, that
the same molecules identified by Scheller and Südhof also regulate the transfer of material between compartments in cells, as well as secretion by the process of exocytosis, thus showing the much broader significance of these proteins to biology in general.
This requires a «de-duplication» step in which multiple reads with the same start site and orientation (presumably
the same molecule) are discarded and only one is kept.