Sentences with phrase «same pathway»

«This is important — it establishes that environmental toxins work on same pathway that is in play in those genetically disposed to Parkinson's.

This is because Blue Origin follows «a lot of the same pathways» as Amazon when building business capabilities, Smith said.

Our brains are literally wired to keep the same pathways, to maintain order and control.

But there are some new dads that have the same pathways activated as drugs,» Caldwell says.

The same pathway that has put many in the seat of a new car — the lease — is taking off as a financial vehicle for homeowners who don't have tens of thousands of dollars sitting around to buy a rooftop solar - panel system outright.

The bigger group seem to be the ones that feel Arsene should have already stepped down by now and feel he churns out the same old stuff and follows the same pathway even when it proves not to work.

The same pathways for beta cell survival and DNA damage repair were also found to be altered in diabetic patient samples, indicating that a genetic predisposition for fragile beta cells may underlie who develops diabetes.

It is the same pathway that helps you generate new hairs naturally as they fall out.

The researchers have yet to show the same pathway is active in human prostate cancers.

This same pathway has been linked to drug resistance in other types of cancer, Guo said.

We may be able to say to a mother with a certain genetic profile, «If you get a fever in this trimester, take Tylenol, because it will bring down the fever and impact the same pathways that increase oxidative stress in susceptible animals we've studied.

Dr. Aron and lead author Xiaomeng Xu, PhD, Assistant Professor of Psychology at Idaho State University, explained that because engaging in self - expanding activities clearly stimulates the same pathways in the brain that are activated by nicotine — as revealed by the fMRI study — self - expanding activities such as games could potentially substitute for the reward the brain receives from nicotine.

Like human LAD patients, these mice had serious periodontal disease early in life, and their gums contained high levels of IL - 17 mRNA and protein, as well as IL - 23, a protein in the same pathway as IL - 17.

A tumor in the lung and a tumor in the breast, for example, may have more in common with one another (and be fueled by abnormalities in the same pathway) than two different breast cancer malignancies.

There is a catch: because each drug is a unique molecular entity, it has the potential to behave slightly differently in the body even if it targets the same pathway as another drug with a sterling record.

If enacted, such a regulatory scheme could conceivably speed along clinical trials because it would allow investigators to draw from a large pool of people with diverse tumors that act along the same pathway instead of culling thousands of people with the same official cancer type.

Different genes could affect the same pathway, meaning that the different genetic anomalies found in people with ASD could potentially all be affecting similar pathways.

«We are not fixing the gene; the mutation is still there,» says Belmonte, «Instead, we are working on the epigenome and the mice recover the expression of other genes in the same pathway.

Instead of trying to correct the mutated gene, the researchers increased the expression of genes in the same pathway as the mutated gene, over-riding the effect of the damaged gene.

Moreover, both pain and empathy can be reduced by a placebo effect that acts on the same pathways as opioid painkillers, the researchers found.

Social neuroscientist Claus Lamm and colleagues at the University of Vienna took a different approach to test whether pain and empathy are driven by the same pathways.

In healthy individuals, these immune checkpoints prevent autoimmunity, but many cancers exploit the same pathways to shield themselves from an immune attack.

It appears unlikely, since that effect would be expected to work through the same pathways already being tested with various mind - body techniques.

This same pathway has been the target for drugs now in advanced clinical trials for treatment of anemia.

«This showed us that C1q and amyloid beta were working together in the same pathway,» Stevens says.

Scientists have succeeded in fleshing out many details of the process, but there was no particular reason to think that other species would control aging with the same pathway.

Meister says there is reason to believe that this same pathway — from rods to horizontal cells to cones — is responsible for the human perception of the color blue in dim light.

The team verified their results in a mouse model and also found evidence of activation of the same pathway in samples from patients with Alexander disease.

Treatments that block this pathway are already showing considerable promise in other malignancies, such as melanoma and lung cancer, leading researchers to question whether this same pathway could be active in malignant pleural mesothelioma.

The brain seemed to be stuck in a rut — using the same pathways over and over again.

It's likely that the drugs that are so effective in enhancing hair growth in the mice could affect the same pathways in human follicles, suggesting they could induce new hair growth and extend the growth of existing hairs in humans.

The discovery could lead to new diabetes drugs that turn off the same pathway in humans.

The researchers also found that IL - 33 levels are increased in the retinas of AMD patients, suggesting that the same pathway may occur in humans.

Though not identical, itch and pain are closely related; they share the same pathways in certain brain areas.

Drosophila shares these same pathways with humans.

They show that the same pathway is responsible for these changes in both cultured cortical and hippocampal neurons from rats and in mice overexpressing Ube3A.

The team found they could replicate the healing abilities of the engineered mice by giving nongenetically altered ones drugs that help activate certain metabolic processes — the same pathway Lin28a stimulates — revving up and energizing cells as if they were much younger.

The findings support the theory that multiple factors within the same pathway may interact to affect one's risk for psychiatric disorders.

We think this may be because the same pathway that causes bone cells to proliferate also helps stem cells to regenerate.»

Additionally, his team will examine indications that the same pathways may be at work in people.

Our work decoding new components of the energy - sensing pathway has also led to new therapeutic targets for many difference forms of cancer, which alter these same pathways through many different mechanisms.»

«It's really interesting to be embedded within the context of the Thomson lab and in the whole stem cell milieu, and understanding how this axolotl might be employing the same pathways that are present in other organisms — and possibly people,» Nelson says.

We've noted that this same pathway is prevalent in glaucoma, and we've shown that these support cells are activated very early in glaucoma.

The slow rise in [Ca2 +] in the IPCs in response to CCHa2 application is consistent with CCHa2 - R's mediation of Dilp release through the same pathway.

«It may have just a subtle influence,» suggests Dr. Cook, «but if we find two more autism - associated genes with the same prevalence — possibly additional hits along the same pathway — 16 percent cubed comes to four in a thousand, close to the frequency of autism.

We think this may be because the same pathway that causes bone cells to proliferate also helps stem cells to regenerate,» said study coauthor Yohei Hayashi.

I'm saying the way that you prevent that from continuing to occur is by making sure those folks have access to treatment, so that when they do get out, they don't go down the same pathway.»

How can blocking the same pathway have the opposite effect in two different types of cells?