If its claims hold, and future research reveals how crayfish blood cells are reprogrammed to become neurons, it could offer new therapeutic ways of doing
the same with human cells.
Not exact matches
Proponents of
human cloning assert that this is the only method of producing pluripotent stem
cells with the
same genetic make - up as adult patients.
First mouse
cells were turned into «totipotent» stem
cells, and now early work suggests the
same might have been achieved
with human cells
Vamsi Mootha, a mitochondrial biologist at Massachusetts General Hospital, his graduate student Isha Jain, and their colleagues used a popular DNA - editing tool called CRISPR to knock out about 18,000 different genes in
human cells that were altered to have the
same problems as people
with mitochondrial diseases.
A new paper published (Nov. 29) in the December issue of Diabetes shows GABA does the
same thing in mice who have been injected
with human pancreatic
cells.
Exploiting the
same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem
cells, and the possibility of identifying combination regimens
with standard chemotherapies
with minimized toxic effects,
with the perspective of their possible application for the treatment of
human breast cancer.
They subsequently treated worms and
human cells with Huntington's disease
with drugs that prevented the
cell from sweeping up and storing the lipid, called ceramide, and saw the
same protective effect.
Prior research
with cultured tissue had shown that a mix of chemicals could change bone marrow stem
cells from mice to those resembling brain
cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the
same brew on
human cells, the number altered was modest.
In previous studies, the
same group along
with others had demonstrated that microRNAs (miRNAs) produced by eukaryotic
cells and viruses are present in
human blood in highly stable,
cell - free forms and these so called circulating miRNAs can serve as non-invasive biomarkers for the early diagnosis of various diseases, including viral diseases.
Strikingly, the researchers noticed the
same signs of axonal demise in spinal cord
cells obtained from
human patients
with ALS.
And many of the highlighted
human genes are associated
with the
same critical cellular operations, such as the
cell's protein - building factories, as in those species, MacArthur's group reports.
Human skin may behave the
same way, which could open the door for new ways to boost blood
cell levels for athletes seeking to gain an edge or patients
with anemia.
He added: «The fact that all vertebrates regenerate their teeth in the
same way
with a set of conserved stem
cells means that we can use these studies in more obscure fishes to provide clues to how we can address questions of tooth loss in
humans.»
Human egg cells behaved the same way; when human ovary tissue was grafted into mice injected with PAH, the eggs died, the team reports in Nature Genetics online this m
Human egg
cells behaved the
same way; when
human ovary tissue was grafted into mice injected with PAH, the eggs died, the team reports in Nature Genetics online this m
human ovary tissue was grafted into mice injected
with PAH, the eggs died, the team reports in Nature Genetics online this month.
Although fragments of DNA called plasmids have been tried for the
same purpose, Nagy says this is the first time a nonviral method has worked
with human cells.
Then last year, scientists showed that they could do the
same thing
with human cells.
These mice have their hemoglobin genes removed and replaced
with the mutated
human version, saddling them
with many of the
same problems as
human sufferers, including immature, short - lived, and sickle - shaped red blood
cells; anemia; reduced blood flow; and an enlarged spleen.
As this work was done
with animal models, we can't yet say whether the stem
cells would thrive in the
same way in a
human brain.
The
same technique — injecting pluripotent stem
cells into early embryos — failed
with other combinations: The scientists couldn't create rat - pig chimeras, and although they produced
human - cow chimeric embryos, they did not transfer them into cows to develop into fetuses.
Thomson's group created
human iPS
cells using fetal lung
cells and foreskin
cells with two of the
same factors as Yamanaka, along
with two different factors.
A few years ago, South Korean scientists said they had done the
same thing
with human cells, but that turned out to be a fraud.
Yamanaka's group used
human adult dermal fibroblasts and induced them to become iPSCs, appearing and functioning like hESCs, by having them express the
same proteins as he used
with mouse
cells: Oct - 4, Sox2, Klf4, and c - Myc (Takahashi et al., 2007).
To whip up a
human clone, doctors would most likely use a process called somatic
cell nuclear transfer — the
same technique they've used successfully
with animals like Dolly, the famous (and now departed) sheep clone.
We now show that astrocytes generated from the
same population of
human fetal glial precursor
cells, by exposure to either bone morphogenetic protein (BMP) or ciliary neurotrophic factor (CNTF), promote widely divergent outcomes
with respect to repairing the injured adult spinal cord.
Two teams independently discover a way to turn ordinary
human skins
cells into stem
cells with the
same characteristics as those derived from
human embryos, a breakthrough that could open the door for advanced medical therapies.
Two teams of scientists have independently discovered a way to turn ordinary
human skin
cells into stem
cells with the
same characteristics as those derived from
human embryos, a breakthrough that could open the door for advanced medical therapies.
They then injected the edited
human cells into seven mice
with compromised immune systems to see if the modified
cells would take hold — a step that would be necessary if the
same procedure were to be done in
humans.
Co-engrafting mice
with human tumors that retain the
same characteristics and
human immune
cells, is a new platform to study the relationship between the
human immune system and tumors and develop immuno - oncology - based cancer therapies.
Whole - body Induced
Cell Turnover (WICT) consists of the qualitative and quantitative coordination of targeted cell ablation with exogenous cell administration so as to effect the replacement of a patient's entire set of endogenous cells with exogenous cells (of the same quantity and cell type as the ablated endogenous cells they are replacing) derived from human pluripotent stem cells and directionally differentiated in vitro prior to their administrat
Cell Turnover (WICT) consists of the qualitative and quantitative coordination of targeted
cell ablation with exogenous cell administration so as to effect the replacement of a patient's entire set of endogenous cells with exogenous cells (of the same quantity and cell type as the ablated endogenous cells they are replacing) derived from human pluripotent stem cells and directionally differentiated in vitro prior to their administrat
cell ablation
with exogenous
cell administration so as to effect the replacement of a patient's entire set of endogenous cells with exogenous cells (of the same quantity and cell type as the ablated endogenous cells they are replacing) derived from human pluripotent stem cells and directionally differentiated in vitro prior to their administrat
cell administration so as to effect the replacement of a patient's entire set of endogenous
cells with exogenous
cells (of the
same quantity and
cell type as the ablated endogenous cells they are replacing) derived from human pluripotent stem cells and directionally differentiated in vitro prior to their administrat
cell type as the ablated endogenous
cells they are replacing) derived from
human pluripotent stem
cells and directionally differentiated in vitro prior to their administration.
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Year 6 Science Assessments and Tracking Objectives covered: Describe how living things are classified into broad groups according to common observable characteristics and based on similarities and differences, including micro-organisms, plants and animals Give reasons for classifying plants and animals based on specific characteristics Identify and name the main parts of the
human circulatory system, and describe the functions of the heart, blood vessels and blood Recognise the impact of diet, exercise, drugs and lifestyle on the way their bodies function Describe the ways in which nutrients and water are transported within animals, including
humans Recognise that living things have changed over time and that fossils provide information about living things that inhabited the Earth millions of years ago Recognise that living things produce offspring of the
same kind, but normally offspring vary and are not identical to their parents Identify how animals and plants are adapted to suit their environment in different ways and that adaptation may lead to evolution Recognise that light appears to travel in straight lines Use the idea that light travels in straight lines to explain that objects are seen because they give out or reflect light into the eye Explain that we see things because light travels from light sources to our eyes or from light sources to objects and then to our eyes Use the idea that light travels in straight lines to explain why shadows have the
same shape as the objects that cast them Associate the brightness of a lamp or the volume of a buzzer
with the number and voltage of
cells used in the circuit Compare and give reasons for variations in how components function, including the brightness of bulbs, the loudness of buzzers and the on / off position of switches Use recognised symbols when representing a simple circuit in a diagram
In 2013
human embryotic stem
cells were created
with the help of the
same method.
Pets are exposed to many of the
same environmental risks as people The cancer
cells are biologically comparable There is a large population of cats and dogs
with pre-existing cases of cancer Cancer occurs in pets within years compared to decades in
humans