Sentences with phrase «sample allele frequency»
SNP calling, genotype calling, and sample allele frequency estimation from new - generation sequencing data Nielsen, R. T. Korneliussen, A. Albrechtsen, Y. Li et al. 2012.
http://www.nielsenlab.org/ Not exact matches
Not only are the alleles skewed between black and white study samples but their frequencies also line up with the groups» overall responses.
In a sample with 26.9 % of CXCR4 alleles disrupted, NHEJ events were detected at a frequency of 2.3 % (170/7531 reads) in an extragenic region on chromosome 12 and 0.8 % (84 / 10531) in ADAMTS17, a metalloprotease of unknown function [45].
Using large - scale empirical and simulated data sets, we found that the sample sizes used in the HapMap project are sufficient to capture common variation, but that performance declines substantially for variants with minor allele frequencies of < 5 %.
In tumor samples, where we frequently encounter variants with a very small allele frequency due to contamination with normal tissue, copy number variation, and tumor heterogeneity, high coverage is essential for accurate detection of these variants with high power.
Therefore, we developed THE REAL McCOIL, Turning HEterozygous SNP data into Robust Estimates of ALelle frequency, via Markov chain Monte Carlo, and Complexity Of Infection using Likelihood, to incorporate polygenomic samples and simultaneously estimate allele frequency and COI.
An analysis of the geographical distribution of allele frequencies showed weak evidence of variation in distribution of alleles, with clusters representing a higher than expected number of samples with the major allele being identified for 5 SNPs.
For the Dutch and Danish samples, only allele frequency data was available.
The differences between the samples are highest in low - frequency alleles and decrease with increasing allele frequency.
Frequency of the mutant MDR1 allele associated with ivermectin sensitivity in a sample population of collies from the northwestern United States.
Samples from 733 privately owned pet MWHDs, 502 females and 191 males, were collected for the purpose of diagnostic genetic testing for canine Lafora disease to determine the genotype and allele frequencies in the tested population.