Sentences with phrase «sample of affected families»

Not exact matches

The case of Nancy Wexler stands out: motivated by her family's history of Huntington's disease, she crossed the globe to collect samples and genealogies from affected families, created a biobank, mapped the gene, and developed both a prenatal and a pre-symptomatic test.

Volunteers can also donate samples of their blood, giving scientists the chance to study tiny differences in DNA that may play a role in how the disorder develops, why it runs in families, how it affects people over time and what makes people vary in their response to treatment.

Family relations within the samples of dogs were a factor that could affect the prevalence found in 2007 and 2009; however, the family relations within the two samples were siFamily relations within the samples of dogs were a factor that could affect the prevalence found in 2007 and 2009; however, the family relations within the two samples were sifamily relations within the two samples were similar.

Since many people are not aware of their legal rights in family law, Mr. Padove dedicates time to fully explain all rights and to protect the best interests of the affected party (see FAQ's about Divorce for a sample).

Long - Term Physical and Mental Health Consequences of Childhood Physical Abuse: Results From a Large Population - Based Sample of Men and Women Springer, Sheridan, Kuo, & Carnes Child Abuse and Neglect: The International Journal, 31 (5), 2007 View Abstract Examines how childhood physical abuse, with the effects of family background and childhood adversities, affects mid-life mental and physical health.

Using archival data drawn from a racially diverse sample of Baltimore youngsters and a seasonal analysis to separate effects of economic standing from family structure, we found that, over winter periods, neither having two parents in the home nor family resources affected growth in standardized achievement.

Validation for preschool MDD (based on meeting all DSM - IV symptom criteria) has been supported by the finding of a specific symptom constellation that was distinct from other psychiatric disorders and stable during a 6 - month period.22 Additionally, alterations in the hypothalamic - pituitary - adrenal axis reactivity similar to those known in adults with depression, greater family history of mood disorders, as well as observational evidence of depressive affects and behaviors were detected in preschoolers with depression, providing further validation.22,25,27 - 30 More recent findings from a larger independent sample (N = 306) ascertained from community sites (and serving as the population for this investigation) have replicated the findings described above and have also demonstrated that preschoolers with depression display significant functional impairment evident in multiple contexts rated by both parents and teachers.24

Thus, the effect of individual vulnerabilities (depressive affect, social anxiety, self - blame, and coping efficacy problems) on the transmission of emotional reactivity in response to conflict from family to peers (friends and romantic partners) was prospectively examined across six waves of data in a community - based sample of 416 adolescents (Mage Wave 1 = 11.90, 51 % girls).

As this tutorial is prepared (2010), the projects below represent a sampling of those funded to address trauma affecting young children birth to five and their families.

Research also needs to adequately control for covariates that may confound the effects of PAE, such as family processes (eg, problematic parenting or family conflict) and parental characteristics, especially maternal substance use.1, 12 Researchers also need to account for genetic liabilities that are shared by parents and offspring.13, 14 A woman's genetic risk of substance use could be passed down to her children and subsequently affect their behavior.15 Research on the consequences of PAE, therefore, needs studies with large samples, with sufficient statistical power to detect small effects, using analytical methods and designs that can account for potential confounds, including factors that are not measured.

In a sample of affected sibling pairs, both maternal history of mood disorder and current ADHD was a predictor of impairment in family functioning [29].