Sentences with phrase «sarcoglycan knockout mice»

As expected, tissue studies of the δ - sarcoglycan knockout mice revealed a distinctively different pattern of muscle damage when compared to the damage the researchers found in knockout mice missing the α - sarcoglycan gene.

Not exact matches

In previous studies, Campbell's team had found that knockout mice lacking α - sarcoglycan had no heart muscle damage, even though their skeletal muscles showed the deterioration typical of MD..

Campbell and his colleagues began their work by genetically engineering knockout mice that lacked a functioning protein called δ - sarcoglycan, which is part of a larger molecular assemblage called the dystrophin - glycoprotein complex (DGC).