Sentences with word «sarcomere»

The addition of sarcomeres in series (and muscle fascicle length) after eccentric training may lead to greater increases in distal muscle size.

Muscle fascicle length increases more after eccentric training than after concentric training (Ema et al. 2016), probably through a larger increase in the number of sarcomeres in series within the myofibrils of a muscle fiber (Brughelli & Cronin, 2007; Butterfield, 2012).

The shortening of the individual sarcomeres in the chain causes the shortening of the myofibrils, and therefore of the muscle fiber itself.

It is thought that this phenomenon is related to the extent to which the individual sarcomeres within the muscle fiber are overlapping (Brughelli & Cronin, 2007).

LVNC is within the diverse spectrum of cardiac morphologies triggered by sarcomere protein gene defects.

Once we have these two pieces of information we can normalize the muscle fiber length, using the following formula: NFL = muscle fiber length x 2.7 μm / average sarcomere length in muscle fiber (μm).

Although in its traditional form, it has always failed to explain some of the fairly fundamental behaviors of muscle contractions, including the history dependence of force production, many researchers believe that it still provides the best explanation for the mechanism by which sarcomeres shorten in order to create tensile force within a muscle fiber.

Decreased neuromuscular performance (6 — 8,29) after static stretching may be attributed to the potential static stretching - induced sarcomere damage.

This can help with inflammation and sarcomere contraction / pumping action much like the benefits of using compression as an initial treatment for an acute injury.

The sliding filament theory predicts that when sarcomeres contract isometrically, the maximum possible force should be proportional to the number of overlapping cross-bridges.

Other cellular and molecular biological changes occur in muscle, including the addition of more sarcomeres (structural units of a muscle cell) to muscle (De Deyne 2001).

The illustration shows a surface representation of the alpha - actinin dimer against a background of muscle sarcomeres viewed under the electron microscope.

Mathias Gautel's team also discovered that, when they destroyed α - actinin's binding site for PIP2 or locked it in a position which can permanently bind titin, ordered sarcomeres were lost; the muscle was broken.

Ultra-structural time - course study in the C. elegans model for Duchenne muscular dystrophy highlights a crucial role for sarcomere - anchoring structures and sarcolemma integrity in the earliest steps of the muscle degeneration process.

* If you would like to learn more about sarcomeres and how muscles work on a much more detailed level, check out this video here by Khan Academy: Sarcomere Length - Tension Relationship *

This is from my training manual: Trigger points form due to a spasm of the muscle, and many will form at once within the numerous sarcomeres due to a problem elsewhere or as a direct insult to the local area.

Positionally meaning, it's position to the ground or it's sarcomere position.»

LDB3 is involved in sarcomere organization and distinctly expressed in Z - discs of heart.

Instead of placing pressure on the origin and insertion points of the muscle, which leads to increase sarcomeres in series, SMR may enhance the thixotropic nature of the fascia enveloping the muscle (see above for more details).

In contrast, the subscapularis only displays extended sarcomeres at maximum shoulder abduction and external rotation, thereby stabilising the shoulder joint in an opposite position (Ward et al. 2006).

We hypothesized that mutations in sarcomere protein genes may be associated with LVNC.

Shortening contractions are caused (almost) entirely by chemical energy being converted into kinetic energy within individual sarcomeres.

Muscle fibers contain chains of sarcomeres in series with one another, arranged in long molecular structures called myofibrils.

The addition of sarcomeres in parallel after concentric training (because of increases in pennation angle) after concentric training may lead to greater increases in muscle size at the mid-point of the muscle (Franchi et al. 2014).

These tests indicate that myomerger - deficient muscle cells called myocytes differentiate and form the contractile unit of muscle (sarcomeres), but they do not join together to form fully functioning muscle tissue.

Titin ensures that the actin and myosin filaments of a sarcomere are positioned correctly and re-adjusts the sarcomere to its original length after muscle activity,» explains structural biologist Kristina Djinović - Carugo.

«Sarcomeres are mainly made up of actin and myosin protein strands called filaments.

The sarcomeres display a typical striated pattern, and are connected via joint Z - discs, seen as dark black and grey diagonal stripes.

The smallest building block of a muscle is the sarcomere, hundreds of which are successively arranged to form muscle fibers.

Depletion of CHC leads to defective costamere formation and maintenance both in vitro and in vivo and induces sarcomere disorganization and a loss of contractile force due to the detachment of sarcomeres from the PM.

Abstract Costameres represent specialized focal adhesion sites of muscle fibres, located between the plasma membrane and sarcomeres, the contractile units of muscle.

The presence or absence of a sarcomere gene mutation in LVNC could not be related to the clinical phenotype.

Ebstein anomaly is within the diverse spectrum of cardiac morphologies triggered by a sarcomere protein gene defect.Our study provides evidence for a link between structural proteins, cardiomyopathy, and congenital heart malformations (Postma et al., 2011).

Genes encoding 6 sarcomere proteins were studied.

MGF acts mainly upon skeletal muscle tissues to bind satellite nuclei into the muscle tissues (sarcomere).

Sarcomeres perform the muscle's contraction with the help of the contractile proteins myosin and actin, which cause the sarcomere to shorten.

They do this by either adding sarcomeres end - to - end in series which will make the muscle cell longer, or by the adding sarcomeres side - by - side in parallel which will make the cell wider.

These muscle cells are composed of myofibrils which consist of repeating sections of sarcomeres.

In the concentric phase, the thin (actin) and thick (myosin) myofilaments of the sarcomeres slide past one another.

Animal experiments performed in the early 1970s (Tabary et al., 1972; Williams and Goldspink, 1973) and later (Ohira et al., 2000) showed a loss of sarcomeres in series when muscles are immobilised in a shortened position.

When calcium ions are released, this causes the sarcomeres to contract.

Longer fascicle lengths likely allow superior contraction velocities, as all the sarcomeres in a myofibril contract at the same time.

Thus, when actively stretching a myofibril, when the average length of each individual sarcomere goes beyond its optimal length for force production, some of the individual sarcomeres lengthen quickly and excessively (called «popping») while others remain shortened.

Excitation - contraction coupling describes the way in which the electrical signal sent through the nervous system leads to muscular contractions at the sarcomere level.

They are made up of chains of sarcomeres in series, and run the full length of the individual muscle fibers (Månsson et al. 2015).