He served as her postdoctoral mentor and, like Foss - Feig,
says autism researchers can learn a lot by studying people with psychosis.
Jiang
said autism researchers worldwide could use the mouse model to study ways to compensate for the gene and improve symptoms in people with autism spectrum disorders and Phelan - McDermid Syndrome, a more profound developmental condition caused by mutations to SHANK3 and other genes in chromosome 22.
The finding is novel,
says autism researcher Peter Mundy at the University of California, Davis, because previous studies of joint attention have not distinguished between initiating and responding.
Not exact matches
And a clinical trial to see whether cord blood transplants improve symptoms of children with
autism spectrum disorder should wrap up in the summer of 2018,
says pediatric
researcher and clinician Joanne Kurtzberg of Duke University, who helped establish a not - for - profit umbilical cord bank in North Carolina.
«Our study was conducted in a supervised setting, by
researchers experienced in working with kids with
autism spectrum disorders who understand the needs and requirements of the animals,» Dr. O'Haire
said.
To close the gap, the
researchers are using technology that facilitates intervention early in the child's life and empowers parents to play a very important role: «baby's first and best teacher,»
said Ashley Darcy - Mahoney, assistant professor and neonatal nurse practitioner at The George Washington University School of Nursing and director of infant research at its
Autism and Neurodevelopmental Disorders Institute.
The ubiquitin finding is «very intriguing,»
says Joachim Hallmayer, an
autism genetics
researcher at Stanford University School of Medicine in Palo Alto, California.
Turning the tide of early deaths linked to
autism must be a priority,
says James Cusack, a campaigning
researcher, who has
autism himself
By crunching data from the genomes of hundreds of individuals with various degrees of
autism, the
researchers identified several functionally related genetic variations that they
say are likely to be linked to
autism or to the underlying pathology of neuronal development that may cause it.
«State laws requiring
autism coverage by private insurers led to increases in autism care: Autism mandates followed by large jump in spending by health plans on care for children with autism, say researchers.&
autism coverage by private insurers led to increases in
autism care: Autism mandates followed by large jump in spending by health plans on care for children with autism, say researchers.&
autism care:
Autism mandates followed by large jump in spending by health plans on care for children with autism, say researchers.&
Autism mandates followed by large jump in spending by health plans on care for children with
autism, say researchers.&
autism,
say researchers.»
The
researchers don't yet know how exactly these genes influence social behavior in either bees or people, but manipulating the genes in honey bees may shed light on what they do in humans,
says Alan Packer, a geneticist at the Simons Foundation in New York City, which funds
autism research, including this bee work.
In Sweden, the 15,000 - strong Somali community calls
autism «the Swedish disease,»
says Elisabeth Fernell, a
researcher at the Karolinska Institute in Stockholm and a co-author of the study.
Though a range of developmental scenarios in multiple brain regions is surely at work in ASDs, the
researchers said the ability to place these specific genetic mutations in one specific set of cells — among hundreds of cell types in the brain, and at a specific point in human development — is a critical step in beginning to understand how
autism comes about.
The findings bolster an emerging link between the immune system and conditions such as
autism,
says lead
researcher Jonathan Kipnis, professor of neuroscience at the University of Virginia in Charlottesville.
Most children who learn more than one language gain valuable skills, and
researchers say this may also be true for children with
autism
«We can not consider
autism as rare a condition as people previously thought,»
says lead
researcher Wei Bao, assistant professor of epidemiology at the University of Iowa.
«The findings may help
researchers evaluate the effects of different
autism therapies,»
said Kaustubh Supekar, PhD, a research associate and the other lead author of the study.
Restating, the
researchers now think that children who have
autism as a consequence of inherited factors have less general cognitive damage than those with severe de novo mutations, which,
says Wigler, in puzzling on the face of it.
«Diminished motor skills appear to be an almost universal property of children with
autism,»
says Professor Michael Wigler, one of three
researchers including Ivan Iossifov from Cold Spring Harbor Laboratory (CSHL) and the New York Genome Center, and Andreas Buja, a statistician from The University of Pennsylvania, who led the team.
Recent research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some children with
autism,
says a leading oncologist and
researcher at the University of Alberta.
Meanwhile, neurobiologist Ricardo Dolmetsch, an
autism researcher at Stanford University in California,
says, «The consensus in the
autism research community, as well as in the stem - cell community, is that there is no scientifically valid reason for using stem cells to treat
autism spectrum disorders».
«A significant part of adulthood is managing health care, which includes regular trips to the doctor, following treatment plans, and being aware of symptoms and changes in health,»
said Nancy Cheak - Zamora, an assistant professor in the MU School of Health Professions and
researcher in the Thompson Center for
Autism and Neurodevelopmental Disorders.
The
researchers say these findings highlight the need for social workers and providers to assist children with
autism as they transition to adulthood.
However,
researchers believe inhalation is likely a major exposure route for people living near heavily treated fields,
said Janie Shelton, an epidemiologist who led a study linking chlorpyrifos to
autism in babies born to moms near treated fields in farm - heavy Northern California last year.
«We need to focus our efforts on addressing the needs of young adults with
autism in a much bigger and broader way,» said Nancy Cheak - Zamora, an assistant professor in the MU School of Health Professions and a researcher at the MU Thompson Center for Autism and Neurodevelopmental Diso
autism in a much bigger and broader way,»
said Nancy Cheak - Zamora, an assistant professor in the MU School of Health Professions and a
researcher at the MU Thompson Center for
Autism and Neurodevelopmental Diso
Autism and Neurodevelopmental Disorders.
«
Researchers at multiple institutions are currently evaluating whether deep - brain stimulation of the amygdala is effective in treating severe cases of
autism or post-traumatic stress disorder,»
says Rutishauser.
John Constantino, a child psychiatrist at Washington University in St. Louis, Missouri,
says that the results are «monumentally important», because there has been little evidence showing that interventions for
autism at an early stage are effective — even though
researchers already broadly endorse the idea.
The research could even have the potential to help
researchers better understand human disabilities, such as
autism, that may involve deficits in social skills, MacLean
said.
Still, Sheehan
said neuroscience already is one of the leaders in data sharing and management, with such resources as the NIH - funded National Database for
Autism Research; an NIH - Defense Department sponsored data base on traumatic brain injury; the NIH - funded Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC), which helps
researchers to develop, share and collaborate on software tools for doing functional and structural imaging studies of the brain; and the Neuroscience Information Framework, an NIH initiative that makes neuroscience resources - data, materials, and tools - accessible via any computer connected to the Internet.
The
researchers say this supports the «female protective effect» hypothesis because females with
autism carry greater genetic load predisposing them to develop the condition, compared to males.
The evidence from MRI scans suggests that such Neanderthal - derived genetic variation may affect the way our brains work today — and may hold clues to understanding deficits seen in schizophrenia and
autism - related disorders,
say the
researchers.
The
researchers say the new techniques developed here will enable them to explore how the disruption of key processes can also cause conditions such as
autism, and will be used in future studies to test possible treatments to prevent brain damage.
But because the number of females with ASD in the ABC Study is small, the
researchers say there is not enough evidence to conclude that the effect is sex - specific, although generally,
autism is more common in males.
The investigation is the largest and the most ethnically diverse study comparing GI problems in children with
autism, developmental delay and typical development, and among the first to examine the relationship between GI symptoms and problem behaviors in children with
autism, the
researchers said.
The
researchers said that understanding the impact of GI problems in children with
autism could provide new insight into more effective and appropriate
autism treatments that could decrease their GI difficulties and that may have the potential to decrease their problem behaviors as well.
«These results indicate that the higher
autism risk may be due mainly to the large numbers of multiple births and complications of pregnancy and delivery among children conceived with ART,»
said Christine Fountain, assistant professor of sociology at Fordham University and affiliated
researcher at Columbia University.
Matthew Anderson, a physician - scientist at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, Massachusetts,
says that the study will encourage other
researchers to explore metabolic pathways as causes of
autism.
It gives developmental psychologists a tool for studying non-verbal children and adults, such as those with
autism,
researchers said.
«The weight of evidence is beginning to suggest that mothers» exposures during pregnancy may play a role in the development of
autism spectrum disorders,»
said Kim Harley, an environmental health
researcher at the University of California, Berkeley who was not involved in the new study.
In his commentary posted on Cleveland.com, Neides, who is a family doctor,
said that preservatives and other ingredients in vaccines are dangerous and are likely behind the increase in diagnosed cases of neurological diseases such as
autism — a claim that has long been discredited by
researchers.
Researchers say it won't be along before they're joined by studies investigating whether the therapy might aid diseases like multiple sclerosis and
autism.
Researchers have come up with a figure that they
say is the most accurate accounting yet for how much of
autism is due to genetic factors.
The
researchers said they can't explain why
autism rates have been increasing across the United States.
Although the
researchers were pleased — and a little surprised — to see the findings so clearly support their hypothesis, the study is just the first in a series they have planned to continue exploring the mind - gut connection, including another examination of the data to see whether a correlation exists between fermented food intake and
autism symptoms,
said Hilimire.
«I think these findings will encourage
researchers to take a second look at drug therapies that have been shown to be effective in schizophrenia but have not been intensively studied for use in
autism,» he
says.
By the time a child starts school, the
autism gender differences can be more magnified,
says Connie Kasari, a
researcher on the NIH study and a professor of psychological studies at the University of California, Los Angeles.
«We've found that while boys and girls with
autism are facing similar problems in school and at home, some of their underlying brain functions are different,» said Kevin Pelphrey, a leading autism researcher and director of the Autism and Neurodevelopmental Disorders Institute at George Washington Unive
autism are facing similar problems in school and at home, some of their underlying brain functions are different,»
said Kevin Pelphrey, a leading
autism researcher and director of the Autism and Neurodevelopmental Disorders Institute at George Washington Unive
autism researcher and director of the
Autism and Neurodevelopmental Disorders Institute at George Washington Unive
Autism and Neurodevelopmental Disorders Institute at George Washington University.