Sentences with phrase «says human geneticist»

That's really the quagmire in this field,» says human geneticist Alfred George of Vanderbilt University in Nashville.

The deCODE whole genomes study is «an amazing piece of work» that «was impossible 5 years ago,» says human geneticist Daniel MacArthur of Massachusetts General Hospital in Boston and the Broad Institute in Cambridge, Massachusetts, who was not involved in the research.

In two studies, researchers have found only «a very small ancient Spanish contribution» to British and Irish DNA, says human geneticist Walter Bodmer of the University of Oxford in the United Kingdom, co-leader of a landmark 2015 study of British genetics.

«There's a potential protective effect here,» says human geneticist Andrew Johnson of the National Heart, Lung, and Blood Institute in Framingham, Massachusetts.

Experts have estimated that such deletions may account for 10 % of all BRCA1 mutations in the U.S. population, says human geneticist Brian Ward, vice president of laboratory operations at Myriad Genetics, one of the main producers of commercial BRCA1 tests.

Not exact matches

If the finding is correct, it indicates that the relationship between humans and Neandertals goes further back and is more complicated than scientists supposed, says Sarah Tishkoff, an evolutionary geneticist at the University of Pennsylvania who was not involved in the study.

«She's not a human geneticist, so she didn't get the job,» says Michael Culbertson, chair of the Genetics Lab at UW Madison.

The genome of the Spirit Cave Mummy is significant because it could help to reveal how ancient humans settled the Americas, says Jennifer Raff, an anthropological geneticist at the University of Kansas in Lawrence.

The data are «very compelling that Neandertals bring back some of the lost ancestral variance,» of modern humans, said geneticist Mait Metspalu of the Estonian Biocentre in Tartu, who heard the talks.

«This means that modern humans emerged earlier than previously thought,» says Mattias Jakobsson, population geneticist at Uppsala University who headed the project together with Stone Age archaeologist Marlize Lombard at the University of Johannesburg.

«If we know the pathways involved, maybe we can reverse this, find better targets and design better drugs,» says Dr. Yutao Liu, vision scientist and human geneticist in the Department of Cellular Biology and Anatomy at the Medical College of Georgia at Augusta University.

Scientists have found a variation of the miR - 182 gene in patients with primary open - angle glaucoma that results in this overexpression, said Dr. Yutao Liu, vision scientist and human geneticist in the Department of Cellular Biology and Anatomy at the Medical College of Georgia at Augusta University.

Matthew Brown, a skeletal geneticist at the University of Oxford says the gene is «a really hot candidate for [human] chondrocalcinosis,» a rare genetic form of joint stiffening that leads to crystal deposition and shows a similarly imbalanced pyrophosphate distribution in the joints.

Mammals, humans included, have circadian clocks that work with the same logic and many of the same gears found in fruit flies, say Jennifer Loros and Jay Dunlap, geneticists at the Geisel School of Medicine at Dartmouth College.

Even for dogs, humans» oldest, closest friends, «all those things are unknown,» says evolutionary geneticist Greger Larson of the University of Oxford.

Hunt - crazy humans weren't the main cause, says geneticist Alan Cooper of the University of Adelaide in Australia.

«It's a nice story that solves a cool mystery — how did Neandertals end up with mtDNA more like that of modern humans,» says population geneticist Ilan Gronau of the Interdisciplinary Center Herzliya in Israel.

«There are certain classes of genes that modern humans inherited from the archaic humans with whom they interbred, which may have helped the modern humans to adapt to the new environments in which they arrived,» says senior author David Reich, a geneticist at Harvard Medical School and the Broad Institute.

«Over the last decade, geneticists have identified hundreds of genetic risk factors for several human diseases, but the functional consequences of those factors on relevant cells are largely unknown,» said Towfique Raj, PhD, BWH Department of Neurology and a postdoctoral scholar at the Broad Institute, lead study author.

«This is a dream site for studying the ancestors of Neanderthals and perhaps modern humans,» says evolutionary geneticist Svante Pääbo.

But one of the geneticists who performed the research says the conclusion is less certain, and according to others we are not even close to knowing the skin colour of any ancient human.

«This change is one that makes all humans different from other animals,» says developmental geneticist David Kingsley, a Howard Hughes Medical Institute investigator at Stanford University.

The researchers don't yet know how exactly these genes influence social behavior in either bees or people, but manipulating the genes in honey bees may shed light on what they do in humans, says Alan Packer, a geneticist at the Simons Foundation in New York City, which funds autism research, including this bee work.

«The idea that social interaction may have facilitated or led to selection for us to be individually recognizable implies that human social structure has driven the evolution of how we look,» said coauthor Michael Nachman, a population geneticist, professor of integrative biology and director of the UC Berkeley Museum of Vertebrate Zoology.

«The virus has never had this many human - to - human transmissions before, and there are a lot of mutations happening,» says Harvard University's Pardis Sabeti, an evolutionary geneticist who co-authored one of the papers.

«It's a hard question who the Celts are,» says population geneticist Stephan Schiffels of the Max Planck Institute for the Science of Human History in Jena, Germany.

Debate over the timing of human origins will continue despite the new evidence from the child, whose remains came from previous shoreline excavations near the town of Ballito Bay, says Uppsala University evolutionary geneticist and study coauthor Mattias Jakobsson.

«This is a very large scale study using a new, innovative statistical method,» said study co-senior author Kenneth S. Kendler, M.D., professor of psychiatry, and human and molecular genetics in the Virginia Commonwealth University School of Medicine, and an internationally recognized psychiatric geneticist.

Peter Forster, a geneticist at the University of Cambridge, says mistakes happen a lot — between 60 percent and 70 percent of published studies of sequences of human mitochondrial DNA contain significant errors.

If four early humans including the hobbit were alive about 40,000 years ago, «the amount of [human] biodiversity... was pretty remarkable,» says geneticist Sarah Tishkoff of the University of Pennsylvania.

Geneticist Dana Carroll of the University of Utah in Salt Lake City, who was at the Napa meeting, says that it will call for discussions of the safety and ethics of using editing techniques on human embryos.

«This is a yeast that lives or dies by human p53 activity,» says Johns Hopkins yeast geneticist Jef Boeke.

The finished atlas, Mazziotta says, will serve a purpose similar to what the Human Genome Project has done for geneticists, providing a detailed framework of the brain that researchers can use to perform experiments.

«This paper represents a significant contribution to our understanding of human environmental adaptation,» says Toomas Kivisild, an evolutionary geneticist at the University of Cambridge in the United Kingdom, who was not involved with the study.

Yet, while scientists have identified several genes that confer specific traits in these species that humans have bred or selected for, such as a special gait in horses, these «are not critical for domestication,» says Leif Andersson, a geneticist at Uppsala University in Sweden.

Such ease of use will likely encourage the use of more animal models in the study of human diseases, says Rhonda Wiler, a geneticist at biotech giant Genentech in San Francisco, California, who co-chairs the Roundtable on Science and Welfare in Laboratory Animal Use (which organized the workshop).

The study, published in the latest issue of the American Journal of Human Genetics represents an important step in our understanding of how the hypothalamus and oxytocin control appetite and behaviour, says Dr Banka, who is also a Consultant Clinical Geneticist at Saint Mary's Hospital at Manchester.

Human geneticist James Noonan of Yale University said that although the approach was «very clever,» speculation about the physiological changes these two deletions caused and the role they played in shaping human evolution is premaHuman geneticist James Noonan of Yale University said that although the approach was «very clever,» speculation about the physiological changes these two deletions caused and the role they played in shaping human evolution is premahuman evolution is premature.

In this case, as in a recent case of gene borrowing between weeds (ScienceNOW, 13 November 2008), «humans were indirect agents in promoting these events,» says Enrico Coen, a geneticist at the John Innes Centre in Norwich, U.K. Geneticist Sheila Schmutz of the University of Saskatchewan in Canada wonders what else the dogs might have contributed to wolves, say, to metabolism or immune systemgeneticist at the John Innes Centre in Norwich, U.K. Geneticist Sheila Schmutz of the University of Saskatchewan in Canada wonders what else the dogs might have contributed to wolves, say, to metabolism or immune systemGeneticist Sheila Schmutz of the University of Saskatchewan in Canada wonders what else the dogs might have contributed to wolves, say, to metabolism or immune system function.

Co-author Heidi Parker, a geneticist at NHGRI, says that because humans initially bred dogs for specific traits — say, smaller body size or calm temperament — selection created a population «bottleneck» that narrowed the genetic variation in offspring, leaving them with just a few specific clusters of variable genetic regions.

«We can't start talking about improved treatments for Maya because diabetes is a very complex disease, involving lots of yet unknown risk factors, says Teresa Tusié Luna, a human geneticist who studies diabetes at the Salvador Zubirán National Institute of Health Sciences and Nutrition in Mexico City.

«It is great to see that what we call the standard model of human evolution gets confirmation from entirely separate evidence,» says population geneticist Luca Cavalli - Sforza of Stanford University in California, the first researcher to trace human migrations with DNA.

Several capacocha mummies have been found on mountains scattered throughout Inca territory, but the Aconcagua boy is «one of the best preserved,» says Antonio Salas, a human geneticist at the University of Santiago de Compostela in Spain and an author of the new study.

Geneticist Kay Davies of the University of Oxford, U.K., says that in order for the approach to be successful in humans, the stem cells will have to be delivered to every muscle.

«I think that this paper clearly rejects the model of selection» posited by Collinge's team, says University of Chicago human geneticist Anna Di Rienzo.

«It's very interesting work that should help us fill in the picture of how human migration is tied to the dissemination of leprosy,» says Daniel Hartl, a population geneticist at Harvard University.

«It's the first example of a circadian clock gene in a human,» says Joseph Takahashi, a geneticist at Northwestern University in Evanston, Illinois.

But it's also possible that these early members of the dog lineage weren't yet tame or living with humans, says Pontus Skoglund, a geneticist at Harvard Medical School who led the study.

«All of these [studies] are pretty important for cancer research,» says cancer geneticist Paul Meltzer of the National Human Genome Research Institute in Bethesda, Maryland.

«Recent increases in chronic diseases like childhood asthma and autism can not be due to major shifts in the human gene pool,» says physician and geneticist Francis Collins, former director of the National Human Genome Research Instihuman gene pool,» says physician and geneticist Francis Collins, former director of the National Human Genome Research InstiHuman Genome Research Institute.