In the health care industry, many life - saving products, such as recombinant therapeutic proteins, vaccines, and gene therapy vectors, are produced from large -
scale cell culture systems.
Many life - saving products, such as recombinant therapeutic proteins, vaccines, and gene therapy vectors, are produced from large -
scale cell culture systems.
Not exact matches
For
cell therapy, automation can be used to increase the
scale of
cell culture operations (e.g., bioreactors replacing flasks) and allow the use of closed
systems that can protect
cell products from contamination with adventitious agents from the environment or operators themselves.
Viral Manufacturing To manufacture viral vectors, two approaches generally are adopted for
culturing purposes:
scale - out of adherent -
cell systems based on 2D planar technologies and
scale - up of 3D suspension
cell cultures in stirred - tank bioreactors.
Due to the large number of hES
cells and human induced Pluripotent Stem (hiPS)
cells needed by I - Stem's research groups, the development of large -
scale culture systems for expansion and differentiation of those
cells is critical.