Sentences with phrase «scale efficacy study»

We hope to move from the safety study into a full scale efficacy study in the spring, involving more patients in centres around the UK and Europe.

Not exact matches

And scientists who conduct human challenge studies, which typically involve a few dozen participants, say they have critical benefits: In addition to saving time and money, they can reveal harm caused by a potential drug or vaccine before it enters large - scale human efficacy trials.

Promising outcomes of preliminary studies in patients in Southeast Asia and parts of Western and Central Africa led the World Health Organization to make the recommendation, but safety and efficacy have not yet been proven in large - scale clinical trials.

The study measured the efficacy of massage therapy treatment by utilizing the Alcohol Withdrawal Scale (AWS), a tool for measuring physiological alcohol withdrawal symptoms such as one - minute radial pulse rate and respiration rate at the beginning and end of each 15 - minute massage or rest interval.

Dr. O'Haire says the valuable data from the pilot study helped secure the NIH R21 grant to conduct the large - scale, clinical trial to further investigate the efficacy and role of service dogs for military veterans with PTSD and their spouses.

Large scale outcome studies were conducted to evaluate the efficacy of anti-depressant treatments including medications and psychotherapies.

Patients and Methods: Validity and reliability of Iranian version of Coping Self - efficacy Scale (CSES) were measured by a cross-sectional study.

Results: Reliability and validity of the scale and its four subscales, such as «stop unpleasant emotions and thoughts» (a = 0.92) «used problem - focused coping» (a = 0.71), Self - efficacy on diabetes problem solving (a = 0.74) and «get support from friends and family» (a = 0.67) were approved explicitly by a psychometric analysis; these show that the scale was slightly valid and reliable on the study setting.

Information regarding the theoretical foundations of MF - PEP has been published previously.21 Pilot studies indicate that MF - PEP is associated with the following: increased knowledge of mood disorders; increased positive family interactions; increased efficacy in seeking treatment; improved coping skills; improved parental attitude toward the child and the treatment; increased social support from parents; and a trend toward increased social support from peers in children.22, 23 To assess the impact of MF - PEP on children's mood symptoms, this full - scale randomized trial was conducted.

While large - scale randomised clinical trials have demonstrated the efficacy of schema therapy (ST) for borderline personality disorder (BPD) and other PDs, current studies are expanding to assess its usefulness for other disorders and particular treatment settings.

Contrary to the meta - analyses of Crits - Christoph5 andAnderson and Lambert, 7 studies of IPT werenot included (eg, Elkin et al30 and Wilfleyet al31), because the relation of IPT to STPPis controversial, and empirical results suggest that IPT is very close toCBT.9 Thus, this review includes only studiesfor which there is a general agreement that they represent models of STPP.As it is questionable to aggregate the results of very different outcome measuresthat refer to different areas of psychological functioning, we assessed theefficacy of STPP separately for target symptoms, general psychiatric symptoms (ie, comorbid symptoms), and social functioning.32 Thisprocedure is analogous to the meta - analysis of Crits - Christoph.5 Asoutcome measures of target problems, we included patient ratings of targetproblems and measures referring to the symptoms that are specific to the patientgroup under study, eg, measures of anxiety for studies investigating treatmentsof anxiety disorders.33 For the efficacy ofSTPP in general psychiatric symptoms, broad measures of psychiatric symptomssuch as the Symptom Checklist - 90 and specific measures that do not refer specificallyto the disorder under study were included; eg, the Beck Depression Inventoryapplied in patients with personality disorders.34, 35 Forthe assessment of social functioning, the Social Adjustment Scale and similarmeasures were included.36

Many states are partnering with academic researchers to study activities, such as scale - up of evidence - based home visiting, the efficacy of enhancements on home visiting models, or the efficacy of infrastructure supports such as state - or county - level centralized intake and screening systems.

The sample reported in this article was part of a large - scale, two - phase demonstration study testing the efficacy of BSFT with high - risk minority youth (first - phase: see above summary of Santisteban, Coatsworth, Perez - Vidal et al., 1997).

More recently, her work has been guided by the growing realization among program evaluators, implementation scientists, and policymakers that a new balance is needed between effectiveness and efficacy studies when investing in program research to guide broad scale replication of evidence based program models.