Sentences with phrase «scale genomic studies»

Large - scale genomic studies on other chlamydial species are giving insights into the biology of these organisms but have not yet been performed on C. abortus.

For many human diseases, large - scale genomic studies have identified common genetic variants that occur more frequently in people with cardiovascular, autoimmune, inflammatory and infectious diseases, diabetes and asthma than in those without these diseases.

Large - scale genomic studies have shown that half of epithelial ovarian cancers (EOCs) have alterations in genes regulating homologous recombination (HR) repair.

Large - scale genomic studies will probably uncover more gene variants associated with increased risk of developing PTSD, says de Quervain, and may provide a better understanding of the molecular mechanisms involved.

The large - scale genomic study of the Scandinavian wolf population is reported in Nature Ecology & Evolution.

Also, a number of large - scale genomics studies have linked variants of the CPEB4 gene with the impairment of fat metabolism.

A large - scale genomic study uncovered novel genetic variants and led researchers to an unexpected gene that affects bone density and fracture risk.

In a large - scale genomic study, published in Science today, a team of researchers led by Uppsala University found that this behaviour might be rooted in their genetic make - up, revealing a likely common evolutionary path that allows for separating populations into novel species.

Not exact matches

The advent of genomics and rapid sequencing techniques has seen HeLa cells used in numerous large - scale studies of gene function and expression.

We provide initial insights into two critical issues: what clinical value can be extracted from different commercial and academic cancer genomic platforms, and how to think about scaling access to that value,» noted the study's Principal Investigator, Robert Darnell, MD, PhD, Robert and Harriet Heilbrunn Professor and Senior Attending Physician at The Rockefeller University and Founding Director of the New York Genome Center.

The perspectives are to upgrade the scale of the functional genomic screen to a genome wide study to get an highlight of all of the biological networks relevant to be targeted for DM1.

In fact, this study reports the largest scale use of massively parallel genomic sequencing (so called next generation sequencing) for medical diagnostics to date and shows that it is practically feasible on a large scale.

Two large - scale studies reveal new insights into the genomic characteristics of childhood cancers.

$ 25M was committed by NHGRI to its Large - Scale Sequencing and Analysis Centers (LSACs) for genomic studies.

Ageing research and more generally the study of the functional basis of human diseases profit enormously from the large - scale approaches and resources in mouse functional genomics: systematic targeted mutation of the mouse genome, systemic phenotyping in mouse clinics, and the archiving and distribution of the mouse resources in public repositories.

«Our study reveals a spectrum of methods that nature uses to allow organisms to adapt to different environments,» said co-senior author Kerstin Lindblad - Toh, Co-Director of SciLifeLab, scientific director of vertebrate genome biology at the Broad Institute and professor in comparative genomics at Uppsala University «These mechanisms are likely also at work in humans and other vertebrates, and by focusing on the remarkably diverse cichlid fishes, we were able to study this process on a broad scale for the first time.»

Recent advances in the scale and diversity of population genomic datasets for bacteria now provide the potential for genome - wide patterns of co-evolution to be studied at the resolution of individual bases.

The branch serves as a focal point at the NIH campus for the analysis of a wide variety of large - scale genomic data generated in the course of laboratory and clinical studies, with branch members actively involved in efforts aimed at developing new bioinformatic approaches for the analysis and visualization of these data.

However, following the flourishing of large - scale genomics, several studies have investigated CNVs across the whole chromosome.

Epidemiologic research is of increasing importance in the era of large scale genomics and databases, where large numbers of patients must be accumulated to study subtle individual effects that translate into large population effects.