Sentences with phrase «scale sequenced human genomes»

Montgomery, S.B., Lappalainen, T., Gutierrez - Arcelus, M. & Dermitzakis, E.T. Rare and common regulatory variation in population - scale sequenced human genomes.

Not exact matches

As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genes.

The advent of large - scale genome sequencing has helped scientists identify DNA bacteriophages in the human gut, skin and blood as well as in the environment, but few researchers have looked for RNA bacteriophages in those samples.

Large - scale genome sequencing efforts, like the Human Microbiome Project, have focused on the community of microorganisms that live in the humanHuman Microbiome Project, have focused on the community of microorganisms that live in the humanhuman gut.

Chaput's method of studying such sequences on a genome - wide scale involves first generating a DNA library of the entire human genome.

Today, the National Human Genome Research Institute (NHGRI) in Bethesda, Maryland, announced it will pour more than $ 116 million into three sequencing centers, which will use «large - scale» sequencing to focus on unraveling the sources of disease and elucidating the workings of disease - causing organisms.

«The availability of the human genome sequence, as well as other genomic resources produced by our sequencing centers, has transformed biomedical research everywhere,» said NHGRI's Associate Director of Extramural Research Jane Peterson, Ph.D., who is also a program director for NHGRI's Large - Scale Sequencing Researcsequencing centers, has transformed biomedical research everywhere,» said NHGRI's Associate Director of Extramural Research Jane Peterson, Ph.D., who is also a program director for NHGRI's Large - Scale Sequencing ResearcSequencing Research Network.

For example, the large - scale sequencing program has already started to sequence the genomes of 100 microorganisms found in the human gut, and will build on this by using genomic sequencing to characterize the complex microbial communities found at many sites in and on the human body.

Last year at around this time, they announced the HiSeq X Ten system, a «factory installation» for human whole genome sequencing (only) at an incredible scale: 18,000 genomes per year, at a cost of $ 1,000 each (for consumables).

HLI has initially purchased two Illumina HiSeq X Ten Sequencing Systems (with the option to acquire three additional systems) to sequence up to 40,000 human genomes per year, with plans to rapidly scale to 100,000 human genomes per year.

There are, however, some low - hanging fruit: promising applications of large - scale human genome sequencing which are likely to yield results.

The National Institute on Aging (NIA) and the National Human Genome Research Institute (NHGRI) were asked to develop and execute a large scale sequencing project to identify AD risk and protective gene variants.

The quality and scale of deCODE's in - house, CLIA - registered genotyping laboratory underpins deCODE's global leadership in the discovery of variations in the sequence of the human genome conferring risk of common diseases.

A few interesting articles in early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.

By leveraging the exponential improvements in the semiconductor industry (known as Moore's Law), the Ion Proton ™ Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human - scale genome to exome to transcriptome sSequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human - scale genome to exome to transcriptome ssequencing applications, ranging from human - scale genome to exome to transcriptome sequencingsequencing.

I have expertise and experience in developing high throughput pipelines for DNA sequencing at large scale, having contributed in a pivotal manner to the sequencing and completion of the Human Genome Project.

His laboratory has also discovered and characterized a significant number of novel genes contributing to autism and human neurodevelopmental disorders, and has recently applied whole - genome sequencing technologies and large - scale genomics datasets to prenatal detection and interpretation of structural variation in the genome.

Over the next three years, the five centers in NHGRI 19s Large - Scale Sequencing Research Network will use high - throughput, robotic technologies to sequence a strategic set of animal genomes totaling as much as 54 billion base pairs, or the equivalent of 18 human genomes.

BETHESDA, Md., Nov. 7, 2003 - The National Human Genome Research Institute (NHGRI) today announced the selection of five centers to carry out a new generation of large - scale sequencing projects designed to maximize the promise of the Human Genome Project and dramatically expand our understanding of human health and disHuman Genome Research Institute (NHGRI) today announced the selection of five centers to carry out a new generation of large - scale sequencing projects designed to maximize the promise of the Human Genome Project and dramatically expand our understanding of human health and disHuman Genome Project and dramatically expand our understanding of human health and dishuman health and disease.

This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross-referencing of mammalian genomes, and validated human transcribed sequences for large - scale studies of gene expression.

To this end, his work often relies on anthropology and human history as much as it does on genome sequencing and computation, in order to decipher the subtle genetic signatures that appear when species undergo major events such as population bottlenecks, large - scale migration or dispersal events, or the development of resistance to disease.

David Reich and colleagues report genome sequences of 300 people from 142 different populations usually under - represented in large - scale studies to describe a range of human variation.